The Mesenchymal Stem Cells found in Teeth are now the most researched Stem Cells in the Scientific Literature.
Dental Stem Cell Research
- Hu, Z, Qin, Z, Yin, L. Effects of astragaloside IV on the proliferation and osteogenic differentiation of human jaw bone marrow mesenchymal stem cells in vitro. Naunyn Schmiedebergs Arch Pharmacol. 2025; :. doi: 10.1007/s00210-025-04475-3. PubMed PMID:40817916 .
- de Souza Araújo, IJ, Perkins, RS, Zhang, W, Krum, SA, Huang, GT. Canonical and Noncanonical WNT-Loaded Hydrogel for Dentin-Pulp Regeneration. J Dent Res. 2025; :220345251357588. doi: 10.1177/00220345251357588. PubMed PMID:40817756 .
- Mahmoud, AH, Sloutski, A, Fu, S, Luo, H, Katevatis, Z, Wong, R et al.. An Innovative Injectable and Retrievable Drug Delivery System for Endodontic Therapy. J Endod. 2025; :. doi: 10.1016/j.joen.2025.08.001. PubMed PMID:40816576 .
- Zheng, Z, Zhang, Y, Xie, M, Lian, W, Zhu, L, Chen, WY et al.. M-keratin induces regeneration of bone tissue in Sprague-Dawley rats. Biomed Mater. 2025; :. doi: 10.1088/1748-605X/adfbdb. PubMed PMID:40814918 .
- Wang, M, Guo, Q, Zhao, W, Dai, Z, Zhu, X, Zhu, X et al.. Investigation of an Injectable Concentrated Growth Factor Gel for Pulp Tissue Regeneration. Aust Endod J. 2025; :. doi: 10.1111/aej.70015. PubMed PMID:40814847 .
- Xie, Y, Li, Y, Xu, C, Zhang, W, Jiang, Y, Wang, L et al.. A cell-free TLR5high MSC membrane nanoparticle therapy for Crohn's disease: Targeted immunomodulation via the flagellin/TLR5 axis. J Control Release. 2025; :114121. doi: 10.1016/j.jconrel.2025.114121. PubMed PMID:40812553 .
- Yoo, YJ, Lee, EH, Bae, J, Kim, WJ, Park, CH, Chung, SH et al.. The dimethyloxalylglycine-functionalized nanofibers for in situ regeneration of infected developing dental roots. Mater Today Bio. 2025;33 :102062. doi: 10.1016/j.mtbio.2025.102062. PubMed PMID:40809404 PubMed Central PMC12343479.
- Fepiosandi, RA, Wahjuningrum, DA, Sampoerno, G, Bhardwaj, A, Pawar, AM. Effect of calcium hydroxide and adipose-derived stem cell conditioned medium (ADSCs-CM) combination on reparative dentin formation in Wistar rats through RUNX-2 and OPN expression. J Oral Biol Craniofac Res. 2025;15 (5):1162-1168. doi: 10.1016/j.jobcr.2025.07.001. PubMed PMID:40808794 PubMed Central PMC12344247.
- Shim, GY, Moon, SH, Shin, SJ, Kim, HJ, Oh, S, Bae, JM et al.. Emodin-Loaded Thermoresponsive Hydrogel as a Potential Drug Delivery System for Periodontal Disease in a Rat Model of Ligature-Induced Periodontitis. Polymers (Basel). 2025;17 (15):. doi: 10.3390/polym17152108. PubMed PMID:40808155 PubMed Central PMC12349398.
- Scibetta, S, Pepe, G, Iuliano, M, Iaiza, A, Palazzo, E, Quadri, M et al.. Polysialylation of Glioblastoma Cells Is Regulated by Autophagy Under Nutrient Deprivation. Int J Mol Sci. 2025;26 (15):. doi: 10.3390/ijms26157625. PubMed PMID:40806752 PubMed Central PMC12347492.
- Ganesh, V, Fredericks, DC, Petersen, EB, Keen, HL, He, R, Turner, JD et al.. Extracellular Vesicles-Induced Cell Homing and Odontogenesis via microRNA Signaling for Dentin Regeneration. Int J Mol Sci. 2025;26 (15):. doi: 10.3390/ijms26157182. PubMed PMID:40806315 PubMed Central PMC12346742.
- Yang, D, Jeong, Y, Ortinau, L, Solidum, JG, Park, D. Mx1-labeled pulp progenitor cells are the main contributors of odontoblast and dentin regeneration in murine molars. Exp Mol Med. 2025; :. doi: 10.1038/s12276-025-01511-3. PubMed PMID:40804477 .
- Kim, M, Kim, R. Physical and biological properties of bioactive glass-containing Bis-GMA-free pulp capping materials: An in vitro study. Dent Mater J. 2025; :. doi: 10.4012/dmj.2024-392. PubMed PMID:40803874 .
- Zhou, H, Wen, P, Liu, Y, Ye, Z, Xiong, W, Liu, Y et al.. MiR-138 reprograms dental pulp stem cells into GABAergic neurons via the GATAD2B/MTA3/WNTs axis for stroke treatment. Biomaterials. 2025;325 :123618. doi: 10.1016/j.biomaterials.2025.123618. PubMed PMID:40803231 .
- Sabry, E, Zayed, HM, Ezzatt, OM, Fathy, I, Elsayeh, HS, El-Khazragy, N et al.. Bee venom exhibits anti-cancer effects on tongue carcinoma cells by arresting cell cycle, inducing apoptosis, and suppressing cell migration. J Appl Oral Sci. 2025;33 :e20250188. doi: 10.1590/1678-7757-2025-0188. PubMed PMID:40802304 .
- Lamprou, A, Porcheri, C, Mitsiadis, TA. Notch2 Deletion Compromises Epithelial Integrity and Enamel Formation in Rodent Incisors. Cells. 2025;14 (15):. doi: 10.3390/cells14151224. PubMed PMID:40801656 PubMed Central PMC12345687.
- El Harane, S, Nazari, B, El Harane, N, Locatelli, M, Zidi, B, Durual, S et al.. Generation of Individualized, Standardized, and Electrically Synchronized Human Midbrain Organoids. Cells. 2025;14 (15):. doi: 10.3390/cells14151211. PubMed PMID:40801645 PubMed Central PMC12346388.
- Lotti, R, Cattuzzato, L, Huang, X, Garandeau, D, Palazzo, E, Quadri, M et al.. Andrographis paniculata Extract Supports Skin Homeostasis by Enhancing Epidermal Stem Cell Function and Reinforcing Their Extracellular Niche. Cells. 2025;14 (15):. doi: 10.3390/cells14151176. PubMed PMID:40801608 PubMed Central PMC12346459.
- Rakshanaa, R, Aswath, N, Ramshankar, V, Ravindran, S, Mehanathan, K. Determination of Salivary CD44 as a Noninvasive Diagnostic Biomarker to Predict Malignant Transformation of Oral Submucous Fibrosis. Contemp Clin Dent. 2025;16 (2):99-103. doi: 10.4103/ccd.ccd_37_25. PubMed PMID:40799232 PubMed Central PMC12338471.
- Jiang, S, Lin, Y, Huang, D, Tan, X. The Effect of the Inflammatory Microenvironment on Odontogenic Differentiation of Dental Pulp Stem Cells. Stem Cells Dev. 2025; :. doi: 10.1177/15473287251366979. PubMed PMID:40794447 .
- Park, SG, Kim, KT, Kim, WJ, Kim, S, Cho, YD. Synergistic epigenetic modulation by 5-aza-2'-deoxycytidine and Wnt3a drives osteogenic trans-differentiation of 3T3-L1 pre-adipocytes through Ywhah and Ywhae. Epigenomics. 2025; :1-11. doi: 10.1080/17501911.2025.2544513. PubMed PMID:40792537 .
- Khan, ZA, Sobkowiak, MJ, Ghorbani, M, Poojabahen, T, Al-Manei, K, Halimi, A et al.. Survival mechanism of pancreatic tumor bacteria and their ability to metabolize chemotherapy drugs. Microbiol Spectr. 2025; :e0182025. doi: 10.1128/spectrum.01820-25. PubMed PMID:40792508 .
- Zhou, Y, Su, Y, Yang, Q, Li, J, Hong, Y, Gao, T et al.. Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes. Nat Neurosci. 2025; :. doi: 10.1038/s41593-025-02027-9. PubMed PMID:40790267 .
- Ghanati, H, Motamedi, S, Fallahpour, S, Bayat, A, Maddahi, M, Kazemi, P et al.. Decoding Noncoding RNAs: Mastering Bone Morphogenetic Protein Signaling and Crosstalk Pathways for Breakthroughs in Periodontal Regeneration. DNA Cell Biol. 2025; :. doi: 10.1177/10445498251362766. PubMed PMID:40788828 .
- Zhao, Y, Peng, Y, Wang, D, Zhang, L, Qiu, Y, Cui, J et al.. PFKFB3-Inhibitor 3PO-Mediated Glycolytic Reprogramming Promotes Inflammatory Dental Pulp Repair: An In Vitro and In Vivo Study. Int Endod J. 2025; :. doi: 10.1111/iej.70016. PubMed PMID:40788622 .
- Huang, MH, Zhao, JY, Shang, XJ, Liu, YJ. [Efficacy and safety of stem cell therapy for erectile dysfunction: A systematic review and Meta-analysis]. Zhonghua Nan Ke Xue. 2025;31 (6):535-546. . PubMed PMID:40788245 .
- Hahn, J, Aksoy, E, Hamad, S, Kuckelkorn, C, Gomez, AM, Ritter, M et al.. Mass Production of Uniform Embryoid Bodies by Acoustic Standing Waves. Small Methods. 2025; :e01283. doi: 10.1002/smtd.202501283. PubMed PMID:40785567 .
- Li, H, Liu, G, Liu, X, Wu, B. The effects and mechanisms underlying collagen-binding peptides MDPs on dentin remineralization: an in vitro study. BMC Oral Health. 2025;25 (1):1307. doi: 10.1186/s12903-025-06680-1. PubMed PMID:40783734 PubMed Central PMC12335033.
- Palmisano, B, Berry, C, Boyce, A, Charles, JF, Collins, MT, Corsi, A et al.. Fibrous dysplasia/McCune-Albright syndrome: state-of-the-art advances, pathogenesis, and basic/translational research. Orphanet J Rare Dis. 2025;20 (1):414. doi: 10.1186/s13023-025-03909-8. PubMed PMID:40781626 PubMed Central PMC12335126.
- Medojevic, M, Mitic, D, Jacimovic, J, Devillard, R, Jakovljevic, A, Kérourédan, O et al.. Extracellular Vesicles-Enhanced 3D (Bio)Printing for Bone Regeneration: A Systematic Review. Tissue Eng Part B Rev. 2025; :. doi: 10.1177/19373341251363638. PubMed PMID:40779416 .
- Sankaralingam, G, Subramaniyan, K, Ezhilarasi, K, Umapathy, D, Rajan Renuka, R, Jothinathan, MD et al.. Induction of ER stress-mediated apoptosis in breast cancer cell line by the powerful alkylating agent bendamustine and insights into its molecular mechanisms. Med Oncol. 2025;42 (9):416. doi: 10.1007/s12032-025-02981-1. PubMed PMID:40779231 .
- Şirinoğlu Çapan, B, Birant, S, Gümüştaş, B, Ercal, P, Sismanoglu, S. Regenerative Strategies in Pediatric Dentistry: A Comprehensive Overview of Tissue Engineering from Past to Future. Adv Exp Med Biol. 2025; :. doi: 10.1007/5584_2025_877. PubMed PMID:40778978 .
- Emerick, C, Silva, LC, Jang, Y, Vargas, PA, Squarize, CH, Castilho, RM et al.. Assessing the selective impact of histone modifying drugs on adenoid cystic carcinoma cells and their stem cell counterparts. BMC Cancer. 2025;25 (1):1277. doi: 10.1186/s12885-025-14739-z. PubMed PMID:40775761 PubMed Central PMC12330070.
- Fernandes, JMS, Pagani, E, Wenceslau, CV, Ynoue, LH, Ferrara, L, Kerkis, I et al.. Phase II trial of intravenous human dental pulp stem cell therapy for Huntington's disease: a randomized, double-blind, placebo-controlled study. Stem Cell Res Ther. 2025;16 (1):432. doi: 10.1186/s13287-025-04557-2. PubMed PMID:40770775 PubMed Central PMC12330078.
- Trevizani, M, Leal, LL, Silva, SAD, Diniz, CG, Costa, FF, Aguiar, JAK et al.. Vegetable peptones as a fetal bovine serum substitute in human deciduous tooth pulp stem cell culture. Einstein (Sao Paulo). 2025;23 :eAO1364. doi: 10.31744/einstein_journal/2025AO1364. PubMed PMID:40767658 PubMed Central PMC12266875.
- Puca, V, Mencarelli, N, Pellegrini, B, Marsich, E, Cataldi, A, Grande, R et al.. Cell Response Toward Inflammation of DPSCs Co-Cultured With Streptococcus mutans in the Presence of Alginate/Hydroxyapatite-Based Scaffolds Enriched With Silver Nanoparticles. J Biomed Mater Res B Appl Biomater. 2025;113 (8):e35636. doi: 10.1002/jbm.b.35636. PubMed PMID:40767096 .
- Kariuki, SW, Mitani, Y, Bailey, DD, Efe, G, Tripathi, VV, Tekin, H et al.. STAT3 regulates basal cell identity and morphogenesis during early esophageal development. bioRxiv. 2025; :. doi: 10.1101/2025.08.01.668154. PubMed PMID:40766660 PubMed Central PMC12324447.
- Naseri, M, Sarfi, S, Hanafi-Bojd, MY, Azaryan, E. Osteogenic potential of human dental pulp stem cells, and human dermal fibroblasts exposed hydroxyapatite nanoparticles: A comparative in vitro study. Int J Mol Cell Med. 2025;14 (2):656-665. doi: 10.22088/IJMCM.BUMS.14.2.656. PubMed PMID:40765752 PubMed Central PMC12321310.
- Mei, P, Tao, X, Ding, Z, Li, R, Zhu, Z, Liu, C et al.. Multifunctional Lithium-Calcium-Silicon Bioceramic Resin Composite for Enhanced Dental Remineralization and Reparative Dentin Formation. Adv Healthc Mater. 2025; :e00530. doi: 10.1002/adhm.202500530. PubMed PMID:40761021 .
- Phothichailert, S, Kornsuthisopon, C, Chansaenroj, A, Trachoo, V, Nowwarote, N, Fournier, B et al.. Decellularised matrices from force loaded periodontal ligament stem cells support osteogenic differentiation. Sci Rep. 2025;15 (1):28387. doi: 10.1038/s41598-025-14343-y. PubMed PMID:40760151 PubMed Central PMC12322110.
- Nakama, H, Matsuo, N, Miyamoto, A, Maeda, H, Yoshikawa, M. Amino Acids Enhance the Effects of Dexamethasone on Osteogenesis by Rat Stem Cells. Tissue Eng Part A. 2025; :. doi: 10.1177/19373341251364546. PubMed PMID:40759462 .
- Fariña, R, Lolas, J, Moreno, E, Soto, F, Romero-Araya, P. Mandibular Defect Reconstruction Using Tissue Engineering: Case Report and Long-Term Follow-Up. J Maxillofac Oral Surg. 2025;24 (4):1125-1133. doi: 10.1007/s12663-025-02624-y. PubMed PMID:40756937 PubMed Central PMC12316641.
- Tang, S, Wang, Y, Ma, P, Fan, Z. Porous titania-coated zirconia: preparation and osteogenic performance evaluation. RSC Adv. 2025;15 (34):27452-27466. doi: 10.1039/d5ra03550c. PubMed PMID:40756663 PubMed Central PMC12315101.
- Terunuma, A, Chiu, CK, Sekine, T, Takane, T, Sekine, Y, Ashiba, K et al.. Proteomic Comparison of Conditioned Media from Mesenchymal Stem Cells of Different Human Tissues: Implications for Therapy. J Stem Cells Regen Med. 2025;21 (1):25-30. doi: 10.46582/jsrm.2101005. PubMed PMID:40756130 PubMed Central PMC12311324.
- Chen, J, Lin, T, Yuan, Y, Wu, P, Dai, S, Xu, H et al.. Comparative Analysis of the Immunomodulatory Functions of Dental Follicle Stem Cells and Their Apoptotic Vesicles. J Stem Cells Regen Med. 2025;21 (1):11-18. doi: 10.46582/jsrm.2101003. PubMed PMID:40756128 PubMed Central PMC12311327.
- Deng, P, Yang, B, Huang, C, Li, Y, Mei, Z, Li, Y et al.. GDF15 promotes osteogenic differentiation of human dental pulp stem cells by activating the TGF-β/SMAD signaling pathway. J Tissue Eng. 2025;16 :20417314251357752. doi: 10.1177/20417314251357752. PubMed PMID:40755460 PubMed Central PMC12314354.
- Zhang, J, Wang, X, Feng, X, Chen, Y, Yu, K, Jiang, Z et al.. Roles and mechanisms of piRNAs in self-renewal and differentiation of germline stem cells. Differentiation. 2025;145 :100897. doi: 10.1016/j.diff.2025.100897. PubMed PMID:40753855 .
- Raut, RD, Chakraborty, AK, Neogi, T, Albro, M, Snyder, B, Schaer, TP et al.. A multi-tissue human knee single-cell atlas identifies that osteoarthritis reduces regenerative tissue stem cells while increasing inflammatory pain macrophages. Commun Biol. 2025;8 (1):1146. doi: 10.1038/s42003-025-08586-8. PubMed PMID:40753276 PubMed Central PMC12317986.
- Kazerooni, MT, Hemmati, S. Cytokines, chemokines, and immune cells involved in oral immunity towards the dental cariogenic bacterium Streptococcus mutans: Therapeutic interventions and vaccination. Biomed Pharmacother. 2025;190 :118394. doi: 10.1016/j.biopha.2025.118394. PubMed PMID:40752424 .
- Tsamesidis, I, Christodoulou, A, Stalika, E, Pouroutzidou, GK, Kontonasaki, E. Innovations in Dental Implants Integration: Optimizing dental implants performance utilizing stem cells and coatings. Biotechnol Prog. 2025; :e70060. doi: 10.1002/btpr.70060. PubMed PMID:40750567 .
- Almanzar, N, Yang, D, Xia, J, Udit, S, Joshi, P, Adhikari, S et al.. Vagal TRPV1+ sensory neurons protect against influenza virus infection by regulating lung myeloid cell dynamics. Sci Immunol. 2025;10 (110):eads6243. doi: 10.1126/sciimmunol.ads6243. PubMed PMID:40749036 .
- Zeng, Y, Yang, L, Wu, N, Chen, H, Zhang, X, Yang, D et al.. A novel biomaterial derived from the skin secretion of Andrias davidianus for dentinal tubule occlusion. J Mater Chem B. 2025; :. doi: 10.1039/d5tb00823a. PubMed PMID:40748262 .
- Saskianti, T, Lorensa, S, Rissandhika, NK, Zahri, AN, Puteri, MM, Wahluyo, S et al.. Histological evaluation of osteogenesis using stem cells from human exfoliated deciduous teeth seeded in polymethylmethacrylate-hydroxyapatite scaffold. J Taibah Univ Med Sci. 2025;20 (4):450-461. doi: 10.1016/j.jtumed.2025.07.001. PubMed PMID:40747358 PubMed Central PMC12312038.
- Gao, J, Wang, Y, Zhang, T, Qu, J, Liu, Q, Chen, Y et al.. Dental pulp stem cells conditioned medium-functionalized microspheres for endodontic regeneration. Front Cell Dev Biol. 2025;13 :1627220. doi: 10.3389/fcell.2025.1627220. PubMed PMID:40746856 PubMed Central PMC12310587.
- Yang, H, Huang, Y, Song, J, Han, X, Yuan, F, Fan, Z et al.. Inhibition of miR-615-3p enhances dentinogenesis in scaps via PVT1-mediated mitochondrial regulation. Stem Cell Res Ther. 2025;16 (1):416. doi: 10.1186/s13287-025-04528-7. PubMed PMID:40745571 PubMed Central PMC12315441.
- Fan, S, Ge, Y, Li, B, Liu, P, Liu, X. Advancements in Microfluidic Organ-on-a-chip for Oral Medicine. Int Dent J. 2025;75 (5):100925. doi: 10.1016/j.identj.2025.100925. PubMed PMID:40743817 PubMed Central PMC12329541.
- Peluso, V, De Santis, R, Gloria, A, Castagliuolo, G, Zanfardino, A, Varcamonti, M et al.. Design of 3D Additive Manufactured Hybrid Scaffolds for Periodontal Repair Strategies. ACS Appl Bio Mater. 2025; :. doi: 10.1021/acsabm.5c00561. PubMed PMID:40742295 .
- Tsuchiya, Y, Matsuo, H, Asahara, H, Inui, M. Matrix stiffness regulates Mkx expression in rat tenocyte through TRPM7. Biochem Biophys Rep. 2025;43 :102178. doi: 10.1016/j.bbrep.2025.102178. PubMed PMID:40740470 PubMed Central PMC12309032.
- Xu, T, Chai, X, Zhang, W, Li, X, Zhang, Y, Zhang, Q et al.. Cell Differentiation of DPSCs Infected With Different Periodontal Pathogens. Oral Dis. 2025; :. doi: 10.1111/odi.70045. PubMed PMID:40739838 .
- Wang, Z, Liu, J, Lin, S, Ye, J, Chen, L, Zhang, C et al.. Endoplasmic Reticulum Stress Inhibits the Neuronal Differentiation of Human Stem Cells From Apical Papillae by Attenuating the Activity of ERK-IRE1α Axis In Vitro. Int Endod J. 2025; :. doi: 10.1111/iej.70003. PubMed PMID:40739653 .
- Luo, X, Xiao, L. Titanium implant can promote M2 polarization with macrophages activation which contribute to osteogenesis and angiogenesis via inactivates JAKS signaling pathway. BMC Immunol. 2025;26 (1):57. doi: 10.1186/s12865-025-00729-0. PubMed PMID:40739176 PubMed Central PMC12309195.
- Liu, Y, Liu, Y, Hu, J, Han, J, Song, L, Liu, X et al.. Impact of allogeneic dental pulp stem cell injection on tissue regeneration in periodontitis: a multicenter randomized clinical trial. Signal Transduct Target Ther. 2025;10 (1):239. doi: 10.1038/s41392-025-02320-w. PubMed PMID:40739139 PubMed Central PMC12311062.
- Khabadze, Z, Dashtieva, M, Chraghyan, L, Begjanov, K, Kirillov, A, Shchetnikova, E et al.. CYTOTOXICITY ASSESSMENT OF ADHESIVE SYSTEM COMPONENTS CONTAINING METHACRYLOYLOXYDECYL DIHYDROGEN PHOSPHATE. Georgian Med News. 2025; (362):16-23. . PubMed PMID:40737643 .
- Yun, YG, Heo, SC, Jung, JW, Yeo, D, Shin, SJ, Tsogtbaatar, K et al.. Mechanosignaling and 3D morphological adaptation of MSCs in response to hydrogel rigidity underpin angiogenic and immunomodulatory efficacy for ischemic injury regeneration. Bioact Mater. 2025;53 :404-416. doi: 10.1016/j.bioactmat.2025.07.027. PubMed PMID:40735355 PubMed Central PMC12305335.
- Voinarovych, S, Maksimov, S, Kaliuzhnyi, S, Kyslytsia, O, Safarova Yantsen, Y, Alontseva, D et al.. Functional Assessment of Microplasma-Sprayed Hydroxyapatite-Zirconium Bilayer Coatings: Mechanical and Biological Perspectives. Materials (Basel). 2025;18 (14):. doi: 10.3390/ma18143405. PubMed PMID:40731615 PubMed Central PMC12298979.
- He, J, Fu, J, Wang, R, Liu, X, Yao, J, Xing, W et al.. Tissue Repair Mechanisms of Dental Pulp Stem Cells: A Comprehensive Review from Cutaneous Regeneration to Mucosal Healing. Curr Issues Mol Biol. 2025;47 (7):. doi: 10.3390/cimb47070509. PubMed PMID:40728978 PubMed Central PMC12293388.
- Parsha, R, Kota, SK. Elavl1 deletion in limb mesenchyme is dispensable for skeletal morphogenesis. Front Cell Dev Biol. 2025;13 :1501837. doi: 10.3389/fcell.2025.1501837. PubMed PMID:40727118 PubMed Central PMC12301689.
- Morano, C, Dei Cas, M, Alessandri, G, Coccè, V, Paino, F, Bignotto, M et al.. Lipid Profile Characterization of Human Micro-Fragmented Adipose Tissue via Untargeted Lipidomics. Biomolecules. 2025;15 (7):. doi: 10.3390/biom15070964. PubMed PMID:40723837 PubMed Central PMC12292148.
- Iglesias, JE, Pinheiro, LS, Ferreira, GC, Cuppini, M, Collares, FM, Grecca, FS et al.. Cetrimide-enhanced Calcium Hydroxide Paste: A Biocompatible and Bioactive Option for Regenerative Endodontics. J Endod. 2025; :. doi: 10.1016/j.joen.2025.07.016. PubMed PMID:40716739 .
- Liu, M, Wang, J, Lv, Y, Sun, Q, Guo, B. Parallel-Shaped poly(L-lactic acid) electrospun membrane promotes facial nerve injury regeneration by upregulating miR-451a expression. J Biomater Sci Polym Ed. 2025; :1-21. doi: 10.1080/09205063.2025.2532569. PubMed PMID:40716052 .
- Bispo, DS, Graça, ICR, Rodrigues, JA, Martins, JTS, Nolasco, MM, Marques, MPM et al.. Exploring In Vitro Mesenchymal Stem Cell Osteodifferentiation via Vibrational Microspectroscopy: A Review. Stem Cell Rev Rep. 2025; :. doi: 10.1007/s12015-025-10943-3. PubMed PMID:40716018 .
- Ju, J, Wang, C, Nie, F, Tian, H, Yin, Q, Liu, J et al.. Progranulin (PGRN) Facilitates Anti-Inflammation and Pulpitis Repair In Vivo and In Vitro Through TNFR2/14-3-3ε Signalling Complex. Int Endod J. 2025; :. doi: 10.1111/iej.70000. PubMed PMID:40717658 .
- Chen, P, Li, J, Telezhkin, V, Gu, Y, Tao, M, Guo, L et al.. Pulsed electromagnetic stimulation promotes neuronal maturation by up-regulating cholesterol biosynthesis. Stem Cell Res Ther. 2025;16 (1):406. doi: 10.1186/s13287-025-04469-1. PubMed PMID:40713855 PubMed Central PMC12297729.
- Lin, M, Fan, L, Qiu, Y, Li, Z, Wang, Y, Cai, X et al.. Polyethyleneimine-modified eggshell membrane for dual bone and periosteum regeneration: A multifunctional approach for guided bone healing. Acta Biomater. 2025; :. doi: 10.1016/j.actbio.2025.07.044. PubMed PMID:40712727 .
- Rath, M, Spinnen, J, Kuhrt, LD, Priglinger, E, Seika, P, Runge, D et al.. Platelet-Rich Plasma - A Comprehensive Review of Isolation, Activation, and Application. Acta Biomater. 2025; :. doi: 10.1016/j.actbio.2025.07.050. PubMed PMID:40712724 .
- Lv, T, Chen, Y, Li, N, Liao, X, Heng, Y, Guo, Y et al.. A Comprehensive Review of Thermosensitive Hydrogels: Mechanism, Optimization Strategies, and Applications. Gels. 2025;11 (7):. doi: 10.3390/gels11070544. PubMed PMID:40710706 PubMed Central PMC12294456.
- Tušas, P, Camilleri, J, Alksnė, M, Šimoliūnas, E, Drukteinis, S, Urbonė, EM et al.. Biocompatibility of Hydraulic Calcium Silicate-Based Cement MTA FlowTM on Human Dental Pulp Stem Cells In Vitro. J Funct Biomater. 2025;16 (7):. doi: 10.3390/jfb16070252. PubMed PMID:40710466 PubMed Central PMC12294829.
- Agnihotri, R, Gaur, S. Therapeutic Applications of Dental Mesenchymal Stem Cells in Alzheimer's Disease-A Scoping Review. Dent J (Basel). 2025;13 (7):. doi: 10.3390/dj13070288. PubMed PMID:40710133 PubMed Central PMC12293466.
- Niibe, K, Begun, DL, Doi-Fujimura, K, Nagasaki, A, Zars, E, Li, X et al.. Inhibition of histone deacetylase 3 in dental mesenchyme regulates the development of tooth root. J Bone Miner Res. 2025; :. doi: 10.1093/jbmr/zjaf102. PubMed PMID:40709765 .
- Liu, J, He, J, Zhang, Z, Liu, L, Cao, Y, Zhang, X et al.. Single-cell transcriptomics identifies PDGFRA+ progenitors orchestrating angiogenesis and periodontal tissue regeneration. Int J Oral Sci. 2025;17 (1):56. doi: 10.1038/s41368-025-00384-6. PubMed PMID:40707447 PubMed Central PMC12289874.
- Del Giudice, C, Rengo, C, Menale, C, Fu Chou, Y, Jovani Sancho, MM, Spagnuolo, G et al.. Assessment of fluoride-infused calcium phosphate resin composites as effective remineralisation agents for human dental pulp stem cells. J Dent. 2025;161 :105997. doi: 10.1016/j.jdent.2025.105997. PubMed PMID:40706657 .
- Qin, TX, Ng, WH, Ng, SK, Zhu, YY, Chek, MF, Tang, KD et al.. Mediator Complex Subunit 27-Enriched Small Extracellular Vesicles Mediate the Crosstalk between Periodontal Bacteria and HPV-Driven Head and Neck Cancer. J Proteome Res. 2025; :. doi: 10.1021/acs.jproteome.5c00373. PubMed PMID:40705947 .
- Fei, Y, Wang, X, Ling, Z, Jiang, Y, Jiang, T, Cao, L et al.. Angiogenic apoptotic vesicle-laden silk fibroin /sodium alginate hydrogel for pulp regeneration. Mater Today Bio. 2025;33 :102060. doi: 10.1016/j.mtbio.2025.102060. PubMed PMID:40704009 PubMed Central PMC12284489.
- Thiruvasagam, S, Nihad, M, Nayak, S, Chaudhury, D, Jose, M, Shenoy, PS et al.. Comparative analysis of periodontal ligament stem cell characteristics in type 2 diabetic and non-diabetic patients with periodontitis. J Oral Maxillofac Pathol. 2025;29 (2):260-268. doi: 10.4103/jomfp.jomfp_9_25. PubMed PMID:40703832 PubMed Central PMC12283043.
- Lopes, RS, Requicha, J, Carolino, N, Costa, E, Carvalho, P. Knowledge of companion animals' practitionerson stem-cell based therapies in a clinical context: a questionnaire-based survey in Portugal. BMC Vet Res. 2025;21 (1):487. doi: 10.1186/s12917-025-04872-z. PubMed PMID:40702466 PubMed Central PMC12288361.
- Kuntjoro, M, Hendrijantini, N, Prasetyo, EP, Atikasari, N, Danaswari, MS, Hong, G et al.. Mechanical and Biological Properties of Nondecellularized Human Wharton's Jelly Matrix for Soft Tissue Graft Material: An In Vitro Study. Eur J Dent. 2025; :. doi: 10.1055/s-0045-1809981. PubMed PMID:40701615 .
- Kyawsoewin, M, Manokawinchoke, J, Termkwanchareon, C, Lwin, HY, Yaklai, S, Limjeerajarus, N et al.. Shear stress-triggered adenosine triphosphate regulates angiogenic properties of human periodontal ligament stem cells. Sci Rep. 2025;15 (1):26589. doi: 10.1038/s41598-025-12323-w. PubMed PMID:40695923 PubMed Central PMC12284249.
- Yang, S, Lei, J, Zheng, K, Nie, J, Zou, C, Wan, Z et al.. An Enzyme-Cleavable Cage on Integrin Adhesive Ligand Regulates Stem Cell Fate in An External Stimulus-Free Manner. Langmuir. 2025;41 (30):20053-20062. doi: 10.1021/acs.langmuir.5c02192. PubMed PMID:40695533 .
- Alania, Y, Reis-Havlat, M, Jing, SX, Tabatabaei, F, McAlpine, JB, Chen, SN et al.. Structure-activity relationships of A-and B-type proanthocyanidins in long-term dentin biomodification and biocompatibility. J Dent. 2025;161 :105988. doi: 10.1016/j.jdent.2025.105988. PubMed PMID:40695440 .
- Zhu, Q, Yin, F, Qin, J, Shi, W, Liu, Y, Zhao, Y et al.. Procr+ chondroprogenitors sense mechanical stimuli to govern articular cartilage maintenance and regeneration. Cell. 2025; :. doi: 10.1016/j.cell.2025.06.036. PubMed PMID:40695281 .
- Sriwattanapong, K, Thaweesapphithak, S, Khamwachirapitak, C, Sae-Ear, P, Prommanee, S, Sa-Ard-Iam, N et al.. FAM20A Deficiency Drives Transcriptomic Dysregulation and Functional Impairment in Gingival Fibroblasts. Cell Prolif. 2025; :e70096. doi: 10.1111/cpr.70096. PubMed PMID:40693438 .
- Giusti, S, Adriani, E, Samuelsson, K, Laudisio, A, Horvath, A, Zampogna, B et al.. The role of arthroscopy in intra-articular adipose tissue-derived mesenchymal stem cells for the treatment of early-stage knee osteoarthritis: A bicentric retrospective comparative study. J Exp Orthop. 2025;12 (3):e70368. doi: 10.1002/jeo2.70368. PubMed PMID:40693217 PubMed Central PMC12277641.
- Brueske, LL, Roffel, S, Beekhuis-Hoekstra, S, de Vries, HE, Gibbs, S. Incorporation of iPSCs together with TERT-immortalized keratinocytes and fibroblasts into reconstructed human gingiva enhances phenotype of gingival epithelium. PLoS One. 2025;20 (7):e0327728. doi: 10.1371/journal.pone.0327728. PubMed PMID:40690428 PubMed Central PMC12279103.
- Usman, S, Yeudall, WA, Teh, MT, Ghloum, F, Tummala, H, Waseem, A et al.. A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer. Elife. 2025;14 :. doi: 10.7554/eLife.104191. PubMed PMID:40690373 PubMed Central PMC12279371.
- De Visscher, J, Vermeir, L, Van den Vreken, N, Temmerman, L, De Roo, N, van Hengel, J et al.. Effect of the pulp harvesting method on the viability of human dental pulp stem cells and their odontogenic differentiation potential. Cell Tissue Bank. 2025;26 (3):32. doi: 10.1007/s10561-025-10183-2. PubMed PMID:40690025 .
- Song, Y, Hu, J, Yang, P, Zhang, Y, Wu, Z, Chen, S et al.. Astragaloside IV Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells via Activating PI3K/AKT/eNOS/NO Signaling Pathway: In vitro and in vivo Study. Drug Des Devel Ther. 2025;19 :6073-6088. doi: 10.2147/DDDT.S514682. PubMed PMID:40687900 PubMed Central PMC12276743.
- de Almeida, LY, Dietrich, C, Hanner, AS, McTighe, KM, Martin, D, NIDCD/NIDCR Genomics and Computational Biology Core et al.. Skeletal Maturity and Age-Related Changes in Immune Cells and Circulatory Factors Impair Large-Scale Bone Regeneration. Aging Cell. 2025; :e70177. doi: 10.1111/acel.70177. PubMed PMID:40685942 .
- Tez, BÇ, Durukan, SM, Yıldır, SK, Çokkeçeci, M, Boyvat, D, Altınsoy, N et al.. Comparative Proteomic Analysis of Dental-Origin Stem Cells: Insights into Regenerative Potential. Stem Cell Rev Rep. 2025; :. doi: 10.1007/s12015-025-10936-2. PubMed PMID:40685492 .
- Wei, XQ, Zhang, SZ. SMURF1 Affects Dental Implant Integration in Diabetes By Regulating PKG2 Expression. Appl Biochem Biotechnol. 2025; :. doi: 10.1007/s12010-025-05326-w. PubMed PMID:40682619 .
- Fawzy El-Sayed, KM, El Moshy, S, Radwan, IA, Rady, D, El-Rashidy, AA, Abbass, MMS et al.. Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential. J Periodontal Res. 2025; :. doi: 10.1111/jre.70015. PubMed PMID:40682345 .
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