Dental Stem Cells

The Mesenchymal Stem Cells found in Teeth are now the most researched Stem Cells in the Scientific Literature.

Dental Stem Cell Research

  1. Kornsuthisopon, C, Photichailert, S, Nowwarote, N, Tompkins, KA, Osathanon, T. Wnt signaling in dental pulp homeostasis and dentin regeneration. Arch Oral Biol. 2021;134 :105322. doi: 10.1016/j.archoralbio.2021.105322. PubMed PMID:34844087 .
  2. Kuwata, F, Ohnishi, H, Yamamoto, N, Takezawa, T, Yamashita, M, Okuyama, H et al.. Transplantation of human iPS cell-derived airway cells on vitrigel membrane into rat nasal cavity. Tissue Eng Part A. 2021; :. doi: 10.1089/ten.TEA.2021.0071. PubMed PMID:34841888 .
  3. Ana, ID, Barlian, A, Hidajah, AC, Wijaya, CH, Notobroto, HB, Kencana Wungu, TD et al.. Challenges and strategy in treatment with exosomes for cell-free-based tissue engineering in dentistry. Future Sci OA. 2021;7 (10):FSO751. doi: 10.2144/fsoa-2021-0050. PubMed PMID:34840808 PubMed Central PMC8609983.
  4. Lopez-Letayf, S, Arie, I, Araidy, S, Abu El-Naaj, I, Pitaru, S, Arzate, H et al.. Human oral mucosa-derived neural crest-like stem cells differentiate into functional osteoprogenitors that contribute to regeneration of critical size calvaria defects. J Periodontal Res. 2021; :. doi: 10.1111/jre.12960. PubMed PMID:34839539 .
  5. Cook, B, Combes, A, Little, M, Osborne, JM. Modelling Cellular Interactions and Dynamics During Kidney Morphogenesis. Bull Math Biol. 2021;84 (1):8. doi: 10.1007/s11538-021-00968-3. PubMed PMID:34837548 .
  6. Aimaitijiang, A, Tabu, K, Wang, W, Nobuhisa, I, Taga, T. Glioma cells remotely promote erythropoiesis as a self-expanding strategy of cancer stem cells. Genes Cells. 2021; :. doi: 10.1111/gtc.12908. PubMed PMID:34837452 .
  7. Mousavi, SM, Yousefi, K, Hashemi, SA, Afsa, M, BahranI, S, Gholami, A et al.. Renewable Carbon Nanomaterials: Novel Resources for Dental Tissue Engineering. Nanomaterials (Basel). 2021;11 (11):. doi: 10.3390/nano11112800. PubMed PMID:34835565 PubMed Central PMC8622722.
  8. Jiang, Q, Bai, G, Liu, X, Chen, Y, Xu, G, Yang, C et al.. 3D GelMA ICC Scaffolds Combined with SW033291 for Bone Regeneration by Modulating Macrophage Polarization. Pharmaceutics. 2021;13 (11):. doi: 10.3390/pharmaceutics13111934. PubMed PMID:34834349 PubMed Central PMC8626002.
  9. Wu, DT, Munguia-Lopez, JG, Cho, YW, Ma, X, Song, V, Zhu, Z et al.. Polymeric Scaffolds for Dental, Oral, and Craniofacial Regenerative Medicine. Molecules. 2021;26 (22):. doi: 10.3390/molecules26227043. PubMed PMID:34834134 PubMed Central PMC8621873.
  10. Kongkiatkamon, S, Ramachandran, A, Knoernschild, KL, Campbell, SD, Sukotjo, C, George, A et al.. Dentin Matrix Protein 1 on Titanium Surface Facilitates Osteogenic Differentiation of Stem Cells. Molecules. 2021;26 (22):. doi: 10.3390/molecules26226756. PubMed PMID:34833848 PubMed Central PMC8621853.
  11. Lee, HJ, Song, YM, Baek, S, Park, YH, Park, JB. Vitamin D Enhanced the Osteogenic Differentiation of Cell Spheroids Composed of Bone Marrow Stem Cells. Medicina (Kaunas). 2021;57 (11):. doi: 10.3390/medicina57111271. PubMed PMID:34833489 PubMed Central PMC8625339.
  12. Fadeeva, IV, Trofimchuk, ES, Forysenkova, AA, Ahmed, AI, Gnezdilov, OI, Davydova, GA et al.. Composite Polyvinylpyrrolidone-Sodium Alginate-Hydroxyapatite Hydrogel Films for Bone Repair and Wound Dressings Applications. Polymers (Basel). 2021;13 (22):. doi: 10.3390/polym13223989. PubMed PMID:34833286 PubMed Central PMC8621946.
  13. Földes, A, Reider, H, Varga, A, Nagy, KS, Perczel-Kovach, K, Kis-Petik, K et al.. Culturing and Scaling up Stem Cells of Dental Pulp Origin Using Microcarriers. Polymers (Basel). 2021;13 (22):. doi: 10.3390/polym13223951. PubMed PMID:34833250 PubMed Central PMC8622966.
  14. Main, BJ, Maffulli, N, Valk, JA, Rodriguez, HC, Gupta, M, El-Amin, SF 3rd et al.. Umbilical Cord-Derived Wharton's Jelly for Regenerative Medicine Applications: A Systematic Review. Pharmaceuticals (Basel). 2021;14 (11):. doi: 10.3390/ph14111090. PubMed PMID:34832872 PubMed Central PMC8618385.
  15. Cirillo, N, Wu, C, Prime, SS. Heterogeneity of Cancer Stem Cells in Tumorigenesis, Metastasis, and Resistance to Antineoplastic Treatment of Head and Neck Tumours. Cells. 2021;10 (11):. doi: 10.3390/cells10113068. PubMed PMID:34831291 PubMed Central PMC8619944.
  16. Tien, N, Lee, JJ, Lee, AK, Lin, YH, Chen, JX, Kuo, TY et al.. Additive Manufacturing of Caffeic Acid-Inspired Mineral Trioxide Aggregate/Poly-ε-Caprolactone Scaffold for Regulating Vascular Induction and Osteogenic Regeneration of Dental Pulp Stem Cells. Cells. 2021;10 (11):. doi: 10.3390/cells10112911. PubMed PMID:34831134 PubMed Central PMC8616324.
  17. La Noce, M, Stellavato, A, Vassallo, V, Cammarota, M, Laino, L, Desiderio, V et al.. Hyaluronan-Based Gel Promotes Human Dental Pulp Stem Cells Bone Differentiation by Activating YAP/TAZ Pathway. Cells. 2021;10 (11):. doi: 10.3390/cells10112899. PubMed PMID:34831122 PubMed Central PMC8616223.
  18. Tadokoro, S, Tokuyama-Toda, R, Tatehara, S, Ide, S, Umeki, H, Miyoshi, K et al.. A New Induction Method for the Controlled Differentiation of Human-Induced Pluripotent Stem Cells Using Frozen Sections. Cells. 2021;10 (11):. doi: 10.3390/cells10112827. PubMed PMID:34831050 PubMed Central PMC8616214.
  19. Mantesso, A, Zhang, Z, Warner, KA, Herzog, AE, Pulianmackal, AJ, Nör, JE et al.. Pulpbow: A Method to Study the Vasculogenic Potential of Mesenchymal Stem Cells from the Dental Pulp. Cells. 2021;10 (11):. doi: 10.3390/cells10112804. PubMed PMID:34831027 PubMed Central PMC8616523.
  20. Asahina, I, Kagami, H, Agata, H, Honda, MJ, Sumita, Y, Inoue, M et al.. Clinical Outcome and 8-Year Follow-Up of Alveolar Bone Tissue Engineering for Severely Atrophic Alveolar Bone Using Autologous Bone Marrow Stromal Cells with Platelet-Rich Plasma and β-Tricalcium Phosphate Granules. J Clin Med. 2021;10 (22):. doi: 10.3390/jcm10225231. PubMed PMID:34830513 PubMed Central PMC8623501.
  21. Sugita, S, Hono, A, Fujino, S, Futatsugi, Y, Yunomae, Y, Shimizu, N et al.. Detection of Mycoplasma Contamination in Transplanted Retinal Cells by Rapid and Sensitive Polymerase Chain Reaction Test. Int J Mol Sci. 2021;22 (22):. doi: 10.3390/ijms222212555. PubMed PMID:34830437 PubMed Central PMC8617609.
  22. Zhao, Z, Sun, Y, Qiao, Q, Zhang, L, Xie, X, Weir, MD et al.. Human Periodontal Ligament Stem Cell and Umbilical Vein Endothelial Cell Co-Culture to Prevascularize Scaffolds for Angiogenic and Osteogenic Tissue Engineering. Int J Mol Sci. 2021;22 (22):. doi: 10.3390/ijms222212363. PubMed PMID:34830243 PubMed Central PMC8621970.
  23. Marconi, GD, Fonticoli, L, Della Rocca, Y, Oliva, S, Rajan, TS, Trubiani, O et al.. Enhanced Extracellular Matrix Deposition on Titanium Implant Surfaces: Cellular and Molecular Evidences. Biomedicines. 2021;9 (11):. doi: 10.3390/biomedicines9111710. PubMed PMID:34829938 PubMed Central PMC8615957.
  24. Aresti, A, Aragoneses, J, López-Valverde, N, Suárez, A, Aragoneses, JM. Effectiveness of Biofunctionalization of Titanium Surfaces with Phosphonic Acid. Biomedicines. 2021;9 (11):. doi: 10.3390/biomedicines9111663. PubMed PMID:34829894 PubMed Central PMC8615956.
  25. Kotova, AV, Lobov, AA, Dombrovskaya, JA, Sannikova, VY, Ryumina, NA, Klausen, P et al.. Comparative Analysis of Dental Pulp and Periodontal Stem Cells: Differences in Morphology, Functionality, Osteogenic Differentiation and Proteome. Biomedicines. 2021;9 (11):. doi: 10.3390/biomedicines9111606. PubMed PMID:34829835 PubMed Central PMC8616025.
  26. Shimizu, Y, Takeda-Kawaguchi, T, Kuroda, I, Hotta, Y, Kawasaki, H, Hariyama, T et al.. Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis. J Periodontal Res. 2021; :. doi: 10.1111/jre.12949. PubMed PMID:34826339 .
  27. Li, W, Mao, M, Hu, N, Wang, J, Huang, J, Gu, S et al.. In vitro evaluation of periapical lesion-derived stem cells for dental pulp tissue engineering. FEBS Open Bio. 2021; :. doi: 10.1002/2211-5463.13336. PubMed PMID:34826215 .
  28. Shin, YY, Seo, Y, Oh, SJ, Ahn, JS, Song, MH, Kang, MJ et al.. Melatonin and verteporfin synergistically suppress the growth and stemness of head and neck squamous cell carcinoma through the regulation of mitochondrial dynamics. J Pineal Res. 2021; :e12779. doi: 10.1111/jpi.12779. PubMed PMID:34826168 .
  29. Pagella, P, Stadlinger, B, Mitsiadis, TA. Isolation of dental pulp and periodontal cells from human teeth for single-cell RNA sequencing. STAR Protoc. 2021;2 (4):100953. doi: 10.1016/j.xpro.2021.100953. PubMed PMID:34825216 PubMed Central PMC8605092.
  30. Song, YM, Lee, HJ, Min, SK, Park, YH, Oh, JK, Kim, JY et al.. Effects of noni on cellular viability and osteogenic differentiation of gingiva-derived stem cells demonstrated by RNA sequencing and quantitative PCR. Exp Ther Med. 2022;23 (1):32. doi: 10.3892/etm.2021.10954. PubMed PMID:34824640 PubMed Central PMC8611496.
  31. Mueller, ML, Ottensmeyer, MP, Thamm, JR, Schmelzeisen, R, Troulis, MJ, Guastaldi, FPS et al.. Increased Osteogenic Activity of Dynamic Cultured Composite Bone Scaffolds: Characterization and In Vitro Study. J Oral Maxillofac Surg. 2021; :. doi: 10.1016/j.joms.2021.10.011. PubMed PMID:34822754 .
  32. Yang, C, Xu, X, Lin, P, Luo, B, Luo, S, Huang, H et al.. Overexpression of long noncoding RNA MCM3AP-AS1 promotes osteogenic differentiation of dental pulp stem cells via miR-143-3p/IGFBP5 axis. Hum Cell. 2021; :. doi: 10.1007/s13577-021-00648-3. PubMed PMID:34822133 .
  33. Kawai, M, Imaizumi, K, Ishikawa, M, Shibata, S, Shinozaki, M, Shibata, T et al.. Long-term selective stimulation of transplanted neural stem/progenitor cells for spinal cord injury improves locomotor function. Cell Rep. 2021;37 (8):110019. doi: 10.1016/j.celrep.2021.110019. PubMed PMID:34818559 .
  34. Damiati, LA, Tsimbouri, MP, Hernandez, VL, Jayawarna, V, Ginty, M, Childs, P et al.. Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials. 2021; :121263. doi: 10.1016/j.biomaterials.2021.121263. PubMed PMID:34810036 .
  35. Sonoda, S, Yoshimaru, K, Yamaza, H, Yuniartha, R, Matsuura, T, Yamauchi-Tomoda, E et al.. Biliary atresia-specific deciduous pulp stem cells feature biliary deficiency. Stem Cell Res Ther. 2021;12 (1):582. doi: 10.1186/s13287-021-02652-8. PubMed PMID:34809720 PubMed Central PMC8607730.
  36. Song, Y, Long, J, Dunkers, JP, Woodcock, JW, Lin, H, Fox, DM et al.. Micromechanical Compatibility between Cells and Scaffolds Directs the Phenotypic Transition of Stem Cells. ACS Appl Mater Interfaces. 2021; :. doi: 10.1021/acsami.1c17504. PubMed PMID:34808061 .
  37. Gao, S, Ge, LH, Zhao, YM, Li, P, Li, YY, Zhao, W et al.. Hsa-miRNA-143-3p regulates the odontogenic differentiation of human stem cells from the apical papilla by targeting NFIC. Int Endod J. 2021; :. doi: 10.1111/iej.13666. PubMed PMID:34807471 .
  38. Sleep, SL, Skelly, D, Love, RM, George, R. Bioenergetics of photobiomodulated osteoblast mitochondrial cells derived from human pulp stem cells: systematic review. Lasers Med Sci. 2021; :. doi: 10.1007/s10103-021-03439-2. PubMed PMID:34806122 .
  39. Alzer, H, Kalbouneh, H, Alsoleihat, F, Abu Shahin, N, Ryalat, S, Alsalem, M et al.. Age of the donor affects the nature of in vitro cultured human dental pulp stem cells. Saudi Dent J. 2021;33 (7):524-532. doi: 10.1016/j.sdentj.2020.09.003. PubMed PMID:34803296 PubMed Central PMC8589584.
  40. Lee, S, Chen, D, Park, M, Kim, SD, Choi, YJ, Moon, SJ et al.. Single cell RNA sequencing analysis of human dental pulp stem cells and human periodontal ligament stem cells. J Endod. 2021; :. doi: 10.1016/j.joen.2021.11.005. PubMed PMID:34801591 .
  41. Garner, SJ, Dalby, MJ, Nobbs, AH, Barbour, ME. A novel chlorhexidine-hexametaphosphate coating for titanium with antibiofilm efficacy and stem cell cytocompatibility. J Mater Sci Mater Med. 2021;32 (12):139. doi: 10.1007/s10856-021-06616-5. PubMed PMID:34800182 .
  42. Wang, JH, He, DE. Simvastatin treatment promotes proliferation of human dental pulp stem cells via modulating PI3K/AKT/miR-9/KLF5 signalling pathway. J Cell Mol Med. 2021; :. doi: 10.1111/jcmm.16973. PubMed PMID:34799978 .
  43. Saggioro, M, D'Agostino, S, Gallo, A, Crotti, S, D'Aronco, S, Corallo, D et al.. A rhabdomyosarcoma hydrogel model to unveil cell-extracellular matrix interactions. Biomater Sci. 2021; :. doi: 10.1039/d1bm00929j. PubMed PMID:34796888 .
  44. Cai, W, Ji, Y, Han, L, Zhang, J, Ni, Y, Cheng, Y et al.. METTL3-Dependent Glycolysis Regulates Dental Pulp Stem Cell Differentiation. J Dent Res. 2021; :220345211051594. doi: 10.1177/00220345211051594. PubMed PMID:34796755 .
  45. Gil-Recio, C, Montori, S, Al Demour, S, Ababneh, MA, Ferrés-Padró, E, Marti, C et al.. Chemically Defined Conditions Mediate an Efficient Induction of Dental Pulp Pluripotent-Like Stem Cells into Hepatocyte-Like Cells. Stem Cells Int. 2021;2021 :5212852. doi: 10.1155/2021/5212852. PubMed PMID:34795766 PubMed Central PMC8593589.
  46. Kanda, K, Asawa, Y, Inaki, R, Fujihara, Y, Hoshi, K, Hikita, A et al.. Requirement of direct contact between chondrocytes and macrophages for the maturation of regenerative cartilage. Sci Rep. 2021;11 (1):22476. doi: 10.1038/s41598-021-01437-6. PubMed PMID:34795319 PubMed Central PMC8602279.
  47. Bartold, M, Ivanovski, S. Stem Cell Applications in Periodontal Regeneration. Dent Clin North Am. 2022;66 (1):53-74. doi: 10.1016/j.cden.2021.06.002. PubMed PMID:34794554 .
  48. Liu, Y, Zhuo, S, Zhou, Y, Ma, L, Sun, Z, Wu, X et al.. Yap-Sox9 signaling determines hepatocyte plasticity and lineage-specific hepatocarcinogenesis. J Hepatol. 2021; :. doi: 10.1016/j.jhep.2021.11.010. PubMed PMID:34793870 .
  49. Koh, KS, Kim, TY, Kwak, YJ, Kim, HJ, Bae, MK, Bae, SK et al.. Natural Herb Mixture Extract Accelerates Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells by Activating the SMAD Pathway. J Med Food. 2021;24 (11):1145-1152. doi: 10.1089/jmf.2021.K.0039. PubMed PMID:34792394 .
  50. Fallah, A, Alipour, M, Jamali, Z, Farjadfar, A, Roshangar, L, Partovi Nasr, M et al.. Overexpression Effects of miR-424 and BMP2 on the Osteogenesis of Wharton's Jelly-Derived Stem Cells. Biomed Res Int. 2021;2021 :7031492. doi: 10.1155/2021/7031492. PubMed PMID:34790821 PubMed Central PMC8592721.
  51. Wang, N, Han, X, Yang, H, Xia, D, Fan, Z. miR-6807-5p Inhibited the Odontogenic Differentiation of Human Dental Pulp Stem Cells Through Directly Targeting METTL7A. Front Cell Dev Biol. 2021;9 :759192. doi: 10.3389/fcell.2021.759192. PubMed PMID:34790668 PubMed Central PMC8591228.
  52. Sun, X, Li, M, Ban, J, Li, Z. miR-23b mediates TNF-α-Inhibited Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Targeting Runx2. Int J Med Sci. 2021;18 (16):3674-3683. doi: 10.7150/ijms.64312. PubMed PMID:34790039 PubMed Central PMC8579284.
  53. Quinelato, V, Bonato, LL, Vieira, AR, Granjeiro, JM, Menezes, K, Borojevic, R et al.. PAX7 gene polymorphism in muscular temporomandibular disorders as potentially related to muscle stem cells. BMC Musculoskelet Disord. 2021;22 (1):959. doi: 10.1186/s12891-021-04846-w. PubMed PMID:34789211 PubMed Central PMC8600756.
  54. Cecoro, G, Guida, L, Iuorio, A, Nucci, L, Pesce, P, Annunziata, M et al.. Cell-based therapies for the surgical treatment of periodontal intrabony defects: a systematic review. Eur Rev Med Pharmacol Sci. 2021;25 (21):6592-6602. doi: 10.26355/eurrev_202111_27102. PubMed PMID:34787862 .
  55. Dawoud, LE, Hegazy, EM, Galhom, RA, Youssef, MM. Photobiomodulation therapy upregulates the growth kinetics and multilineage differentiation potential of human dental pulp stem cells-an in vitro Study. Lasers Med Sci. 2021; :. doi: 10.1007/s10103-021-03461-4. PubMed PMID:34787763 .
  56. He, Y, Guan, X, Du, Y, Liu, G, Li, Y, Wei, Z et al.. Screening of differentially expressed miRNAs during osteogenic/odontogenic differentiation of human dental pulp stem cells exposed to mechanical stress. Am J Transl Res. 2021;13 (10):11126-11143. . PubMed PMID:34786047 PubMed Central PMC8581937.
  57. Jiang, H, Zhong, J, Li, W, Dong, J, Xian, CJ, Shen, YK et al.. Gentiopicroside promotes the osteogenesis of bone mesenchymal stem cells by modulation of β-catenin-BMP2 signalling pathway. J Cell Mol Med. 2021; :. doi: 10.1111/jcmm.16410. PubMed PMID:34783166 .
  58. Hamada, A, Mukasa, H, Taguchi, Y, Akagi, E, Obayashi, F, Yamasaki, S et al.. Identification of a familial cleidocranial dysplasia with a novel RUNX2 mutation and establishment of patient-derived induced pluripotent stem cells. Odontology. 2021; :. doi: 10.1007/s10266-021-00674-5. PubMed PMID:34779963 .
  59. He, Y, Tian, M, Li, X, Hou, J, Chen, S, Yang, G et al.. A Hierarchical-Structured Mineralized Nanofiber Scaffold with Osteoimmunomodulatory and Osteoinductive Functions for Enhanced Alveolar Bone Regeneration. Adv Healthc Mater. 2021; :e2102236. doi: 10.1002/adhm.202102236. PubMed PMID:34779582 .
  60. Subbiah, R, Balbinot, GS, Athirasala, A, Collares, FM, Sereda, G, Bertassoni, LE et al.. Nanoscale mineralization of cell-laden methacrylated gelatin hydrogels using calcium carbonate-calcium citrate core-shell microparticles. J Mater Chem B. 2021; :. doi: 10.1039/d1tb01673c. PubMed PMID:34779469 .
  61. Abaricia, JO, Whitehead, AJ, Kandalam, S, Shah, AH, Hotchkiss, KM, Morandini, L et al.. E-cigarette Aerosol Mixtures Inhibit Biomaterial-Induced Osseointegrative Cell Phenotypes. Materialia (Oxf). 2021;20 :. doi: 10.1016/j.mtla.2021.101241. PubMed PMID:34778733 PubMed Central PMC8589285.
  62. Hermans, F, Hemeryck, L, Lambrichts, I, Bronckaers, A, Vankelecom, H. Intertwined Signaling Pathways Governing Tooth Development: A Give-and-Take Between Canonical Wnt and Shh. Front Cell Dev Biol. 2021;9 :758203. doi: 10.3389/fcell.2021.758203. PubMed PMID:34778267 PubMed Central PMC8586510.
  63. Victor, AK, Donaldson, M, Johnson, D, Miller, W, Reiter, LT. Molecular Changes in Prader-Willi Syndrome Neurons Reveals Clues About Increased Autism Susceptibility. Front Mol Neurosci. 2021;14 :747855. doi: 10.3389/fnmol.2021.747855. PubMed PMID:34776864 PubMed Central PMC8586424.
  64. Al-Serwi, RH, El-Kersh, AOFO, El-Akabawy, G. Human dental pulp stem cells attenuate streptozotocin-induced parotid gland injury in rats. Stem Cell Res Ther. 2021;12 (1):577. doi: 10.1186/s13287-021-02646-6. PubMed PMID:34775989 PubMed Central PMC8591949.
  65. Winning, L, El Karim, IA, Linden, GJ, Irwin, CR, Killough, SA, Lundy, FT et al.. Differential regulation of NPY and SP receptor expression in STRO-1+ve PDLSCs by inflammatory cytokines. J Periodontal Res. 2021; :. doi: 10.1111/jre.12952. PubMed PMID:34773642 .
  66. Bar, JK, Lis-Nawara, A, Grelewski, PG. Dental Pulp Stem Cell-Derived Secretome and Its Regenerative Potential. Int J Mol Sci. 2021;22 (21):. doi: 10.3390/ijms222112018. PubMed PMID:34769446 PubMed Central PMC8584775.
  67. Hollý, D, Klein, M, Mazreku, M, Zamborský, R, Polák, Š, Danišovič, Ľ et al.. Stem Cells and Their Derivatives-Implications for Alveolar Bone Regeneration: A Comprehensive Review. Int J Mol Sci. 2021;22 (21):. doi: 10.3390/ijms222111746. PubMed PMID:34769175 PubMed Central PMC8583713.
  68. Park, KR, Park, JE, Kim, B, Kwon, IK, Hong, JT, Yun, HM et al.. Calycosin-7-O-β-Glucoside Isolated from Astragalus membranaceus Promotes Osteogenesis and Mineralization in Human Mesenchymal Stem Cells. Int J Mol Sci. 2021;22 (21):. doi: 10.3390/ijms222111362. PubMed PMID:34768792 PubMed Central PMC8583672.
  69. Liu, Y, Fan, L, Lin, X, Zou, L, Li, Y, Ge, X et al.. Functionalized self-assembled peptide RAD/Dentonin hydrogel scaffold promotes dental pulp regeneration. Biomed Mater. 2021;17 (1):. doi: 10.1088/1748-605X/ac3928. PubMed PMID:34768244 .
  70. Maru, V, Madkaikar, M, Shabrish, S, Kambli, P, Dalvi, A, Setia, P et al.. Evaluation and comparison of cytotoxicity and bioactivity of chemomechanical caries removal agents on stem cells from human exfoliated deciduous teeth. Eur Arch Paediatr Dent. 2021; :. doi: 10.1007/s40368-021-00684-5. PubMed PMID:34766278 .
  71. Li, C, Mills, Z, Zheng, Z. Novel cell sources for bone regeneration. MedComm (2020). 2021;2 (2):145-174. doi: 10.1002/mco2.51. PubMed PMID:34766140 PubMed Central PMC8491221.
  72. Huang, JL, Oshi, M, Endo, I, Takabe, K. Clinical relevance of stem cell surface markers CD133, CD24, and CD44 in colorectal cancer. Am J Cancer Res. 2021;11 (10):5141-5154. . PubMed PMID:34765317 PubMed Central PMC8569346.
  73. Mai, Z, Chen, H, Ye, Y, Hu, Z, Sun, W, Cui, L et al.. Translational and Clinical Applications of Dental Stem Cell-Derived Exosomes. Front Genet. 2021;12 :750990. doi: 10.3389/fgene.2021.750990. PubMed PMID:34764982 PubMed Central PMC8576041.
  74. Raj, AT, Kheur, S, Bhonde, R, Mani, VR, Baeshen, HA, Patil, S et al.. Assessing the effect of human dental pulp mesenchymal stem cell secretome on human oral, breast, and melanoma cancer cell lines. Saudi J Biol Sci. 2021;28 (11):6556-6567. doi: 10.1016/j.sjbs.2021.07.029. PubMed PMID:34764771 PubMed Central PMC8568833.
  75. Yamashita, K, Tomokiyo, A, Ono, T, Ipposhi, K, Alhasan, MA, Tsuchiya, A et al.. Mineral trioxide aggregate immersed in sodium hypochlorite reduce the osteoblastic differentiation of human periodontal ligament stem cells. Sci Rep. 2021;11 (1):22091. doi: 10.1038/s41598-021-01545-3. PubMed PMID:34764383 PubMed Central PMC8585953.
  76. Lyu, P, Li, B, Li, P, Bi, R, Cui, C, Zhao, Z et al.. Parathyroid Hormone 1 Receptor Signaling in Dental Mesenchymal Stem Cells: Basic and Clinical Implications. Front Cell Dev Biol. 2021;9 :654715. doi: 10.3389/fcell.2021.654715. PubMed PMID:34760881 PubMed Central PMC8573197.
  77. Nazhvani, FD, Kazempour, S, Hosseini, SM, Nazhvani, AD, Haddadi, P. Regeneration of dentin-pulp complex by using dental pulp stem cells in dog. Dent Res J (Isfahan). 2021;18 :86. . PubMed PMID:34760077 PubMed Central PMC8554473.
  78. Bhandi, S, Alkahtani, A, Mashyakhy, M, Ali Baeshen, H, Mustafa, M, Chohan, H et al.. Study of optimal conditions for growth and osteogenic differentiation of dental pulp stem cells based on glucose and serum content. Saudi J Biol Sci. 2021;28 (11):6359-6364. doi: 10.1016/j.sjbs.2021.06.101. PubMed PMID:34759755 PubMed Central PMC8568704.
  79. Kumbar, VM, Muddapur, UM, Bhat, KG, Shwetha, HR, Kugaji, MS, Peram, MR et al.. Cancer Stem Cell Traits in Tumor Spheres Derived from Primary Laryngeal Carcinoma Cell Lines. Contemp Clin Dent. ;12 (3):247-254. doi: 10.4103/ccd.ccd_252_20. PubMed PMID:34759681 PubMed Central PMC8525812.
  80. Shimizu, K, Gi, M, Suzuki, S, North, BJ, Watahiki, A, Fukumoto, S et al.. Interplay between protein acetylation and ubiquitination controls MCL1 protein stability. Cell Rep. 2021;37 (6):109988. doi: 10.1016/j.celrep.2021.109988. PubMed PMID:34758305 PubMed Central PMC8621139.
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