The Mesenchymal Stem Cells found in Teeth are now the most researched Stem Cells in the Scientific Literature.
Dental Stem Cell Research
- Shen, Y, Wang, L, Guo, Z, Wang, J, Zhang, R, Tang, C et al.. METTL14 promotes TBK1 mRNA stability through IGF2BP3-recognized m6A modification and enhances mitophagy in BMSCs. Cell Signal. 2025; :111873. doi: 10.1016/j.cellsig.2025.111873. PubMed PMID:40381973 .
- Nan, DN, Praneetpong, N, Bulanawichit, W, Chantarangsu, S, Everts, V, Ferreira, JN et al.. Biomechanical force-primed periodontal ligament stem cells exhibit a tolerance effect against bacterial inflammation. J Dent. 2025; :105820. doi: 10.1016/j.jdent.2025.105820. PubMed PMID:40381879 .
- He, F, Zhu, J, Zeng, X, Jiang, L, Zhang, L. Effects of Porphyromonas gingivalis lipopolysaccharide on the behavior of human dental pulp stem cells in vitro and their inflammation-related transcriptomics profile. Arch Oral Biol. 2025;176 :106295. doi: 10.1016/j.archoralbio.2025.106295. PubMed PMID:40381466 .
- Zhang, XH, He, YD, Wang, H, Cao, Y, Ying, SQ, Liu, JN et al.. Development-Inspired Biomimetic Cell-Niche Coaggregates Safeguard Tooth Stem Cell-Based Functional Tissue Regeneration. Adv Healthc Mater. 2025; :e2501550. doi: 10.1002/adhm.202501550. PubMed PMID:40376872 .
- Wang, Y, Tu, M, Gao, H, Deng, S. Impacts of Circular RNAs on the Osteogenic Differentiation of Dental Stem Cells. Stem Cells Int. 2025;2025 :8338337. doi: 10.1155/sci/8338337. PubMed PMID:40376229 PubMed Central PMC12081154.
- Assoratgoon, I, Nowwarote, N, Phothichailert, S, Dissanayaka, WL, Samaranayake, LP, Osathanon, T et al.. Unravelling the role of interleukin-6 in regulating dental stem cell behaviour: a scoping review. BMC Oral Health. 2025;25 (1):732. doi: 10.1186/s12903-025-06097-w. PubMed PMID:40375224 PubMed Central PMC12082909.
- Ubara, Y, Kono, K, Hoshino, J, Wada, T, Wake, A, Ohashi, K et al.. Trend of treatment strategy for amyloid light-chain amyloidosis: a-single center experience. Clin Exp Nephrol. 2025; :. doi: 10.1007/s10157-025-02696-7. PubMed PMID:40372551 .
- Dallos Ortega, M, Aveyard, J, Magdy Abdelgawad, R, El-Gendy, R, Ciupa, A, Whetnall, D et al.. Antimicrobial 3D printed gelatin scaffolds for root canal disinfection in regenerative endodontics procedures. Biomater Sci. 2025; :. doi: 10.1039/d5bm00440c. PubMed PMID:40372258 .
- Dadhich, P, Pal, P, Dogra, N, Srivas, PK, Das, B, Das, S et al.. Calcium Phosphate Apatite Filament Co-Wrapped With Perforated Electrospun Sheet of Phosphorylated Chitosan-A Bioinspired Approach Toward Bone Graft Substitute. J Biomed Mater Res B Appl Biomater. 2025;113 (5):e35589. doi: 10.1002/jbm.b.35589. PubMed PMID:40371991 .
- Li, L, Wu, J, Liu, L, Zhang, P, Zhang, Y, Zhou, Z et al.. Photothermal Antibacterial Effect of Gold Nanostars Coating on Titanium Implant and Its Osteogenic Performance. Int J Nanomedicine. 2025;20 :5983-5999. doi: 10.2147/IJN.S519183. PubMed PMID:40370805 PubMed Central PMC12075448.
- Cheng, D, Yuan, X, Ma, Z, Lin, X, Zhu, Z, Wang, J et al.. Canonical Wnt Pathway Enhanced Dental Pulp Mesenchymal Stem Cells-Mediated Cementum Regeneration. J Oral Rehabil. 2025; :. doi: 10.1111/joor.14001. PubMed PMID:40369784 .
- Dong, R, Li, M, Gu, XF, Gao, H, Wei, Z, Qi, H et al.. The surface protein Gbp of Fusobacterium nucleatum inhibits osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2. J Transl Med. 2025;23 (1):540. doi: 10.1186/s12967-025-06569-1. PubMed PMID:40369630 PubMed Central PMC12080044.
- Shimizu, T, Miyoshi, M, Kakinuma, S, Tsuchiya, J, Yamane, D, Watakabe, K et al.. Bile acid-FXR signaling facilitates the long-term maintenance of hepatic characteristics in human iPSC-derived organoids. Cell Rep. 2025; :115675. doi: 10.1016/j.celrep.2025.115675. PubMed PMID:40367952 .
- Zamorano, M, Aguilar-Gallardo, C, Lugo, A, Jimenez, L, Farias, JG, Mantalaris, A et al.. Engineering an Integrated Bioprocess to Produce Human Dental Pulp Stem Cell-Alginate-Based Bone Organoids. Int J Mol Sci. 2025;26 (9):. doi: 10.3390/ijms26094348. PubMed PMID:40362585 PubMed Central PMC12073084.
- Ni, Z, Cai, L, Tsai, IC, Ding, W, Tian, C, Li, D et al.. NAT10 Regulates LPS-Induced Inflammation via Stabilization of N4-Acetylated PTX3 mRNA in Human Dental Pulp Stem Cells. Int J Mol Sci. 2025;26 (9):. doi: 10.3390/ijms26094325. PubMed PMID:40362562 PubMed Central PMC12072506.
- Liu, J, Chen, Y, Li, Z, Li, Z, Lyu, F, Wang, F et al.. Human dental pulp stem cells attenuate airway inflammation in mice with PM2.5-induced asthma exacerbation by inhibiting the pyroptosis pathway. Stem Cell Res Ther. 2025;16 (1):240. doi: 10.1186/s13287-025-04368-5. PubMed PMID:40361181 PubMed Central PMC12076901.
- Park, S, Kim, JE, Lee, J, Kim, W, Choi, W, Lee, MC et al.. Bioimplant-on-a-Chip for Facile Investigation of Periodontal Ligament Formation on Biogenic Hydroxyapatite/Ti6Al4 V Implants. ACS Appl Mater Interfaces. 2025; :. doi: 10.1021/acsami.5c04687. PubMed PMID:40359253 .
- Atia, GA, Abdal Dayem, A, Taher, ES, Alghonemy, WY, Cho, SG, Aldarmahi, AA et al.. Urine-derived stem cells: a sustainable resource for advancing personalized medicine and dental regeneration. Front Bioeng Biotechnol. 2025;13 :1571066. doi: 10.3389/fbioe.2025.1571066. PubMed PMID:40357329 PubMed Central PMC12066649.
- Zhang, Q, Cao, S, Zhang, M, Wu, D, Zhang, C, Li, J et al.. Biodentine Counteracts the Aging Process of Human Dental Pulp Stem Cells Through Wnt/β-Catenin Pathway. Int Dent J. 2025;75 (4):100819. doi: 10.1016/j.identj.2025.03.028. PubMed PMID:40354696 .
- Brümmer, N, Doll-Nikutta, K, Schadzek, P, Mikolai, C, Kampmann, A, Wirth, D et al.. Better models, better treatment? a systematic review of current three dimensional (3D) in vitro models for implant-associated infections. Front Bioeng Biotechnol. 2025;13 :1569211. doi: 10.3389/fbioe.2025.1569211. PubMed PMID:40352353 PubMed Central PMC12061920.
- Maleki, L, Fattahi, B, Razavi, SM, Shekarian, M, Eskandari, S. CD44 and EPCAM expression in pleomorphic adenoma and mucoepidermoid carcinoma: An immunohistochemical method. Dent Res J (Isfahan). 2025;22 :16. doi: 10.4103/drj.drj_545_24. PubMed PMID:40351859 PubMed Central PMC12063989.
- Ma, Y, Ghosh, S, Kong, X, Kalimuthu, S, Pudipeddi, A, Okuro, K et al.. Nanoscale bismuth infused bioadhesive gelatin methacryloyl electrospun mats demonstrate excellent antibiofilm activity and biocompatibility. Int J Biol Macromol. 2025;312 :144103. doi: 10.1016/j.ijbiomac.2025.144103. PubMed PMID:40350112 .
- Ahmad, P, Estrin, N, Farshidfar, N, Zhang, Y, Miron, RJ. Glucagon-Like Peptide 1 Receptor Agonists (GLP-1RAs) Improve Periodontal and Peri-Implant Health in Type 2 Diabetes Mellitus. J Periodontal Res. 2025; :. doi: 10.1111/jre.13410. PubMed PMID:40348599 .
- Pilbauerova, N, Dasi, D, De Souza Araujo, IJ, Huang, GT. An in vitro tube model for cell biocompatibility study of capping materials for regenerative endodontics. J Endod. 2025; :. doi: 10.1016/j.joen.2025.04.018. PubMed PMID:40348362 .
- Sedek, EM, Holiel, AA. Next-Generation Strategies for Enamel Repair and Regeneration: Advances in Biomaterials and Translational Challenges. Tissue Eng Regen Med. 2025; :. doi: 10.1007/s13770-025-00725-w. PubMed PMID:40347432 .
- Garcia-de-Albeniz, N, Müller, DW, Mücklich, F, Ginebra, MP, Jiménez-Piqué, E, Mas-Moruno, C et al.. Tailoring Cell Behavior and Antibacterial Properties on Zirconia Biomaterials through Femtosecond Laser-Induced Micropatterns and Nanotopography. ACS Appl Mater Interfaces. 2025; :. doi: 10.1021/acsami.4c22433. PubMed PMID:40347147 .
- Gu, X, Wei, W, Wu, C, Sun, J, Wu, X, Shen, Z et al.. Profiling and functional characterization of long noncoding RNAs during human tooth development. Int J Oral Sci. 2025;17 (1):38. doi: 10.1038/s41368-025-00375-7. PubMed PMID:40346090 PubMed Central PMC12064826.
- Saito, R, Hasebe, M, Hara, T, Tanegashima, K. Expression cloning of cell surface receptors for the CpG oligodeoxynucleotide/CXCL14 complex. Biochem Biophys Res Commun. 2025;768 :151954. doi: 10.1016/j.bbrc.2025.151954. PubMed PMID:40345012 .
- Zhang, Y, Zhang, Y, Chen, Y, Wu, W, Sun, J, Zhang, X et al.. Impact of intercellular adhesion molecule 1-positive dental pulp stem cells in deep caries progression. Int Endod J. 2025; :. doi: 10.1111/iej.14248. PubMed PMID:40343788 .
- Jiang, W, Duan, S, Li, W, Yan, H, Si, C, Xu, N et al.. PDGF-BB overexpressing dental pulp stem cells improve angiogenesis in dental pulp regeneration. Front Bioeng Biotechnol. 2025;13 :1578410. doi: 10.3389/fbioe.2025.1578410. PubMed PMID:40343206 PubMed Central PMC12058851.
- Song, GJ, Oh, SH, Lee, JH, Lee, M, Hwang, HS, Koh, JT et al.. Photo-curable layered double hydroxide-hyaluronic acid-composite hydrogels with multifunctional properties for growth factor-free bone regeneration. Int J Biol Macromol. 2025; :143980. doi: 10.1016/j.ijbiomac.2025.143980. PubMed PMID:40339864 .
- Recka, N, Simons, A, Cornell, RA, Van Otterloo, E. Epidermal loss of PRMT5 leads to the emergence of an atypical basal keratinocyte-like cell population and defective skin stratification. J Invest Dermatol. 2025; :. doi: 10.1016/j.jid.2025.04.008. PubMed PMID:40339790 .
- Behzadi, P, Wendling, AA, Cuevas, RA, Crane, A, Chu, CC, Moorhead, WJ 3rd et al.. Rapamycin Reduces Arterial Mineral Density and Promotes Beneficial Vascular Remodeling in a Murine Model of Severe Medial Arterial Calcification. Am J Physiol Heart Circ Physiol. 2025; :. doi: 10.1152/ajpheart.00530.2024. PubMed PMID:40338175 .
- Rossi, A, Ferrari, G, Galli, V, Bonacini, M, Carnevale, G, Pisciotta, A et al.. Immunomodulatory effects of dental pulp stem cells on lymphocytes and monocytes from patients with rheumatoid arthritis. Clin Exp Rheumatol. 2025;43 (5):809-814. doi: 10.55563/clinexprheumatol/l64k20. PubMed PMID:40338061 .
- Yang, S, Liu, J, Khe, JS, Lu, AJH, Lim, V. Emerging insights into mesenchymal stem cells and exosome-based therapies for liver injury. Biomol Biomed. 2025; :. doi: 10.17305/bb.2025.12144. PubMed PMID:40338014 .
- Aga, N, McGregor, S, Jones, S, Ellis, I, Tatullo, M, Hassan, MEM et al.. EFFICACY OF STEM CELLS IN ENDODONTIC REGENERATION: A SYSTEMATIC REVIEW. J Evid Based Dent Pract. 2025;25 (2):102125. doi: 10.1016/j.jebdp.2025.102125. PubMed PMID:40335194 .
- Cecilia, PH, Narmada, IB, Ridwan, RD, Ernawati, DS, Bramantoro, T, Rianti, D et al.. Adipose-Derived Mesenchymal Stem Cell Osteodifferentiation after Exposure to Beta-Tricalcium Phosphate Bioceramic Granules with 300 to 600 and 600 to 1,000 µm Sizes. Eur J Dent. 2025; :. doi: 10.1055/s-0045-1806964. PubMed PMID:40334681 .
- Aliaga-Gálvez, R, Gutiérrez, MF, Valenzuela, B, Geraldeli, S, Abuna, G, Inostroza, C et al.. The Incorporation of Copper-Doped Bioactive Glass Nanoparticles into Resin Composites Improves Their Biological, Mechanical and Adhesive Properties. J Adhes Dent. 2025;27 :103-114. doi: 10.3290/j.jad.c_2014. PubMed PMID:40331405 PubMed Central PMC12057575.
- Wang, Y, Fang, C, Mao, LB, Feng, YH, Meng, YF, Wang, HC et al.. A novel Liesegang-patterned mineralized hydrogel drives bone regeneration with microstructure control. Mater Today Bio. 2025;32 :101775. doi: 10.1016/j.mtbio.2025.101775. PubMed PMID:40331154 PubMed Central PMC12053635.
- Tajpara, P, Sobkowiak, MJ, Healy, K, Naud, S, Gündel, B, Halimi, A et al.. Patient-derived pancreatic tumor bacteria exhibit oncogenic properties and are recognized by MAIT cells in tumor spheroids. Front Immunol. 2025;16 :1553034. doi: 10.3389/fimmu.2025.1553034. PubMed PMID:40330456 PubMed Central PMC12053177.
- Parisay, I, Moodi, M, Boskabady, M, Bagheri, H, Salari, R, Hoseinzadeh, M et al.. Physical and drug- releasing properties of a cement containing simvastatin (SimCeram). BMC Oral Health. 2025;25 (1):684. doi: 10.1186/s12903-025-06045-8. PubMed PMID:40325441 PubMed Central PMC12051323.
- Jeon, HH, Salas, MCC, Park, K, Fisher, L, Ha, S, Palmer, C et al.. Comparison of the bone remodeling in the midpalatal suture during maxillary expansion between young and middle-aged mice. Bone. 2025;197 :117512. doi: 10.1016/j.bone.2025.117512. PubMed PMID:40324615 .
- Tomalka, JA, Owings, A, Galeas-Pena, M, Ziegler, CGK, Robinson, TO, Wichman, TG et al.. Enhanced Production of Lipid Mediators in Plasma and Activation of DNA Damage Pathways in PBMCs Are Correlated With the Severity of Ancestral SARS-CoV-2 Infection. FASEB J. 2025;39 (9):e70600. doi: 10.1096/fj.202403195R. PubMed PMID:40322970 .
- Shen, D, Li, Y, Shi, J, Zhang, T, Nie, JJ, Chen, D et al.. Biodegradable Zn-Li-Mn alloy to achieve optimal strength and ductility for bone implants. Acta Biomater. 2025; :. doi: 10.1016/j.actbio.2025.04.056. PubMed PMID:40318745 .
- Hu, Y, Wang, Y, Liu, Y, Dai, J, Wang, J, Ju, C et al.. Injectable laponite nanocomposite hydrogel with synergistic antibacterial and odontogenic activity for endodontic regeneration. Colloids Surf B Biointerfaces. 2025;253 :114745. doi: 10.1016/j.colsurfb.2025.114745. PubMed PMID:40318397 .
- Khaseb, S, Kohansal Vajari, M, Soufi Zomorrod, M, Rezai Rad, M, Ajami, M, Ajami, M et al.. Effect of fibrin on the expression of adhesion molecules (ICAM-1, ITGAV, and ITGB3) in unrestricted somatic stem cells. Hematol Transfus Cell Ther. 2025;47 (2):103827. doi: 10.1016/j.htct.2025.103827. PubMed PMID:40315755 .
- Ding, R, Chen, C, Wang, L, Wang, Y, Chai, Z, He, S et al.. Matrix Stiffness Regulates the Osteogenic Differentiation of hPDLSCs via DNA Methylation. Int Dent J. 2025;75 (4):100783. doi: 10.1016/j.identj.2025.02.022. PubMed PMID:40315698 .
- Hu, Y, Huang, G, Dai, Z, Yang, R, Zhang, Y, Zhang, Y et al.. Artificial Cell-Derived Vesicles: Extracellular Vesicle Mimetics for Chondrocyte Restoration in TMJOA Therapy. Int J Nanomedicine. 2025;20 :5393-5405. doi: 10.2147/IJN.S508449. PubMed PMID:40313864 PubMed Central PMC12044611.
- Margono, A, Pratiwi, RS, Nofarina, AD, Npa, DA, Maharti, ID, Rosseti, R et al.. Biocompatibility and Bioactivity Evaluation of Novel Calcium Silicate-Based Sealer: In Vitro Study on Human Dental Pulp Stem Cells. Eur J Dent. 2025; :. doi: 10.1055/s-0045-1802566. PubMed PMID:40311629 .
- Al Shehadat, S, Rani, A, Shehadat, OA, Abou Neel, EA, Yadadi, SS, Al-Rawi, N et al.. Investigating the Effects of Bead Formation on the Physicochemical and Biological Properties of Electrospun Poly(lactic-co-glycolic Acid) (PLGA) Membranes: A Comparative Analysis. Eur J Dent. 2025; :. doi: 10.1055/s-0045-1804885. PubMed PMID:40311626 .
- Sharma, R, Holtzman, NG, Pusic, I, Cutler, CS, Treister, N, Mehta, RS et al.. Belumosudil reduces oral chronic graft-versus-host disease tissue inflammation and fibrosis: a ROCKstar companion study. Blood Adv. 2025; :. doi: 10.1182/bloodadvances.2025016170. PubMed PMID:40311075 .
- Li, Y, Jiang, B, Wu, Z, Ma, Z, Qiu, L, Cui, W et al.. Engineering fibroblast with reprogramming and spheronization for bone defect repair. Bioact Mater. 2025;50 :414-431. doi: 10.1016/j.bioactmat.2025.04.021. PubMed PMID:40309255 PubMed Central PMC12041790.
- Iwasaki, A, Hatakeyama, M, Liu, Q, Orimoto, A, Fukuda, T, Kitaoka, T et al.. Proliferation and differentiation of human dental pulp stem cells on phosphorylated cellulose nanofiber scaffolds. Carbohydr Polym. 2025;359 :123593. doi: 10.1016/j.carbpol.2025.123593. PubMed PMID:40306767 .
- Umapathy, VR, Natarajan, PM, Swamikannu, B. Regenerative Strategies in Dentistry: Harnessing Stem Cells, Biomaterials and Bioactive Materials for Tissue Repair. Biomolecules. 2025;15 (4):. doi: 10.3390/biom15040546. PubMed PMID:40305324 PubMed Central PMC12025071.
- Janbaz, P, Behzadpour, F, Ghanadan, K. Evaluation of the Structural, Biological, and Bone Induction Properties of Sol-Gel-Derived Lithium-Doped 68S Bioactive Glass-An in Vitro Study on Human Dental Pulp Stem Cells. Clin Exp Dent Res. 2025;11 (3):e70139. doi: 10.1002/cre2.70139. PubMed PMID:40304308 PubMed Central PMC12042117.
- Surisaeng, T, Wisitrasameewong, W, Champaiboon, C, Sa-Ard-Iam, N, Chanamuangkon, T, Thongnuek, P et al.. BMP-2 mRNA-transfected BMSCs promote superior calvarial bone regeneration. Sci Rep. 2025;15 (1):15022. doi: 10.1038/s41598-025-99979-6. PubMed PMID:40301548 PubMed Central PMC12041208.
- Mante, N, Undale, V, Sanap, A, Bhonde, R, Tambe, P, Bansode, M et al.. Disease microenvironment preconditioning: An evolving approach to improve therapeutic efficacy of human mesenchymal stromal cells. Int Immunopharmacol. 2025;157 :114701. doi: 10.1016/j.intimp.2025.114701. PubMed PMID:40300358 .
- Wen, C, Chen, X, Lai, L. Identifying metabolic biomarkers and pathways in pulpitis: a metabolomic study using ultra-high-performance liquid chromatography/orbitrap mass spectrometry. J Appl Oral Sci. 2025;33 :e20240428. doi: 10.1590/1678-7757-2024-0428. PubMed PMID:40298663 PubMed Central PMC12061451.
- Gultekin, SE, Arslan Bozdag, L, Odenthal, M, Dienes, HP. Epigenetic Regulation of Dental Follicle Stem Cells in Odontogenic Regeneration. J Cell Mol Med. 2025;29 (9):e70541. doi: 10.1111/jcmm.70541. PubMed PMID:40296331 PubMed Central PMC12037698.
- Sleep, SL, Ranjit, E, Gunter, J, Hryciw, DH, Arany, P, George, R et al.. Mitochondrial Oxygen Consumption and Immunocytochemistry of Human Dental Pulp Stem Cell Following 808 nm PBM Therapy: A 3D Cell Culture Study. J Biophotonics. 2025; :e70051. doi: 10.1002/jbio.70051. PubMed PMID:40294940 .
- Naidu, P, Das, M, Hansda, S, Prateeksha, P, Howlader, MSI, Siraj, MA et al.. Mechanisms of Ellagic Acid (EA)-Mediated Osteogenic Differentiation of Human Dental Pulp-Derived Stem Cells. ACS Omega. 2025;10 (15):15229-15242. doi: 10.1021/acsomega.4c10642. PubMed PMID:40290905 PubMed Central PMC12019503.
- Ma, S, Yao, S, Li, Y, Yang, Y, Tong, T, Zheng, H et al.. A pH-Responsive Polyetheretherketone Implant Modified with a Core-Shell Metal-Organic Framework to Promote Antibacterial and Osseointegration Abilities. Biomater Res. 2025;29 :0188. doi: 10.34133/bmr.0188. PubMed PMID:40290761 PubMed Central PMC12022397.
- Anselmi, C, Mendes Soares, IP, Chang, S, Cardoso, LM, de Carvalho, ABG, Dal-Fabbro, R et al.. Quercetin-calcium hydroxide scaffolds modulate dental pulp stem cell response in vitro under a simulated inflammatory environment. Int Endod J. 2025; :. doi: 10.1111/iej.14243. PubMed PMID:40285990 .
- Garg, N, Krishna, R, Urs, AB, Kumar, P, Augustine, J. A systematic review on the molecular pathways of Ameloblastic carcinoma when compared to Ameloblastoma. Expert Rev Mol Diagn. 2025; :1-13. doi: 10.1080/14737159.2025.2499180. PubMed PMID:40285826 .
- Paraš, S, Petrović, B, Mitić, D, Lazarević, M, Popović Bajić, M, Živković, M et al.. Three-Dimensional-Printed Bone Grafts for Simultaneous Bone and Cartilage Regeneration: A Promising Approach to Osteochondral Tissue Engineering. Pharmaceutics. 2025;17 (4):. doi: 10.3390/pharmaceutics17040489. PubMed PMID:40284484 PubMed Central PMC12030389.
- Sillmann, YM, Eber, P, Orbeta, E, Wilde, F, Gross, AJ, Guastaldi, FPS et al.. Milestones in Mandibular Bone Tissue Engineering: A Systematic Review of Large Animal Models and Critical-Sized Defects. J Clin Med. 2025;14 (8):. doi: 10.3390/jcm14082717. PubMed PMID:40283548 PubMed Central PMC12027812.
- Zhu, Y, Ge, X, Chen, Z, Chen, T, Wu, Y, Wen, H et al.. METTL3-m6A methylase regulates the osteo-/odontogenic potential of stem cells from apical papilla via NFIC in apical periodontitis. Exp Cell Res. 2025;448 (2):114576. doi: 10.1016/j.yexcr.2025.114576. PubMed PMID:40280320 .
- Boisen, IM, Krarup Knudsen, N, Nielsen, JE, Kooij, I, Bagger, ML, Kaludjerovic, J et al.. Changes in local mineral homeostasis facilitate the formation of benign and malignant testicular microcalcifications. Elife. 2025;13 :. doi: 10.7554/eLife.95545. PubMed PMID:40279260 PubMed Central PMC12029210.
- Stieger, RB, Lilaj, B, Hönigl, GP, Pock, S, Cvikl, B. Flow Cytometry Illuminates Dental Stem Cells: a Systematic Review of Immunomodulatory and Regenerative Breakthroughs. Stem Cell Rev Rep. 2025; :. doi: 10.1007/s12015-025-10883-y. PubMed PMID:40279028 .
- Zhao, HR, Zhao, JZ, Zhao, N, Xue, LF, Xu, YX, Yue, J et al.. CA1 induced dental follicle stem cells co-culture with dental pulp stem cells and loaded three-dimensional printed PCL/β-TCP scaffold: a novel strategy for alveolar cleft bone regeneration. J Mater Sci Mater Med. 2025;36 (1):37. doi: 10.1007/s10856-025-06889-0. PubMed PMID:40278949 PubMed Central PMC12031973.
- Seciu-Grama, AM, Lazăr, SE, Petrescu, S, Mocioiu, OC, Crăciunescu, O, Atkinson, I et al.. Impact of Vitamin D3 Functionalization on the Osteogenic Capacity of Bioinspired 3D Scaffolds Based on Ce-Doped Bioactive Glass and Spongia Agaricina. J Funct Biomater. 2025;16 (4):. doi: 10.3390/jfb16040141. PubMed PMID:40278249 PubMed Central PMC12027579.
- Mitic, DD, Milosevic Markovic, MS, Jovanovic, ID, Mancic, DD, Orhan, K, Jokanovic, VR et al.. A Biomimetic Approach to Diode Laser Use in Endodontic Treatment of Immature Teeth: Thermal, Structural, and Biological Analysis. Biomimetics (Basel). 2025;10 (4):. doi: 10.3390/biomimetics10040216. PubMed PMID:40277616 PubMed Central PMC12025333.
- Kim, H, Williams, SJ, Colombo, JS. Characterization of Fibronectin-Adherent, Non-Fibronectin-Adherent, and Explant-Derived Human Dental Pulp Stem Cell Populations. Dent J (Basel). 2025;13 (4):. doi: 10.3390/dj13040159. PubMed PMID:40277489 PubMed Central PMC12026221.
- Yu, L, Yang, F, Li, C, Ruan, J, Wang, J. Poly(amidoamine) Dendrimers as Potential Therapeutic Agents for Conservative Treatment of Irreversible Pulpitis. J Endod. 2025; :. doi: 10.1016/j.joen.2025.04.007. PubMed PMID:40274259 .
- Zhang, Q, Yi, Y, Chen, T, Ai, Y, Chen, Z, Liu, G et al.. M2 microglia-derived small extracellular vesicles modulate NSC fate after ischemic stroke via miR-25-3p/miR-93-5p-TGFBR/PTEN/FOXO3 axis. J Nanobiotechnology. 2025;23 (1):311. doi: 10.1186/s12951-025-03390-2. PubMed PMID:40270025 PubMed Central PMC12020034.
- Budi, HS, Handajani, J, Amir, LR, Soekanto, SA, Ulfa, NM, Wulansari, SA et al.. Nanoemulgel Development of Stem Cells from Human Exfoliated Deciduous Teeth-Derived Conditioned Medium as a Novel Nanocarrier Growth Factors. Eur J Dent. 2025; :. doi: 10.1055/s-0045-1806963. PubMed PMID:40267955 .
- Belludi, SA, Shaik, S, Pradhan, N, Rema, S. Treatment of an endodontic-periodontal lesion using peripheral blood mesenchymal stem cells (PBMSCs) and platelet-rich fibrin matrix (PRFM): A case report. J Adv Periodontol Implant Dent. 2025;17 (1):54-58. doi: 10.34172/japid.025.3502. PubMed PMID:40265038 PubMed Central PMC12010481.
- Hu, M, Wu, L, Wei, E, Pan, X, Zhu, Q, Xiuyun, X et al.. Sildenafil promotes osteogenic differentiation of human mesenchymal stem cells and inhibits bone loss by affecting the TGF-β signaling pathway. Stem Cell Res Ther. 2025;16 (1):201. doi: 10.1186/s13287-025-04320-7. PubMed PMID:40264229 PubMed Central PMC12016470.
- Hammad, M, Dugué, J, Maubert, E, Baugé, C, Boumédiene, K. Decellularized apple hypanthium as a plant-based biomaterial for cartilage regeneration in vitro: a comparative study of progenitor cell types and environmental conditions. J Biol Eng. 2025;19 (1):38. doi: 10.1186/s13036-025-00502-2. PubMed PMID:40264116 PubMed Central PMC12012941.
- Wang, L, Liu, T, Zhang, W, Liu, H, Qi, Y, Li, M et al.. BMAL1-downregulation drives PANoptosis and the osteogenic differentiation impairment of PDLSCs by ERK/AP-1 signaling pathway. J Periodontol. 2025; :. doi: 10.1002/JPER.24-0497. PubMed PMID:40259757 .
- Acharya, JR, Kumar, S, Girdhar, GA, Patel, S, Parekh, NH, Patadiya, HH et al.. 3D Bioprinting: Shaping the Future of Periodontal Tissue Regeneration and Disease Management. Cureus. 2025;17 (4):e82432. doi: 10.7759/cureus.82432. PubMed PMID:40255528 PubMed Central PMC12007905.
- Al Hamwi, G, Alnouri, MW, Verdonck, S, Leonczak, P, Chaki, S, Frischbutter, S et al.. Subnanomolar MAS-related G protein-coupled receptor-X2/B2 antagonists with efficacy in human mast cells and disease models. Signal Transduct Target Ther. 2025;10 (1):128. doi: 10.1038/s41392-025-02209-8. PubMed PMID:40254631 PubMed Central PMC12010006.
- Ku, D, Yang, Y, Park, Y, Jang, D, Lee, N, Lee, YK et al.. SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases. Cell Rep. 2025;44 (5):115588. doi: 10.1016/j.celrep.2025.115588. PubMed PMID:40253699 .
- Takahara, S, Ohkura, N, Yoshiba, N, Baldeon-Gutierrez, R, Gomez-Kasimoto, S, Edanami, N et al.. Influence of Tooth Maturity on Healing Outcomes in Regenerative Endodontics. J Dent Res. 2025; :220345251325826. doi: 10.1177/00220345251325826. PubMed PMID:40251757 .
- Karimi, M, Sheibani Pour, M, Etemadi, A, Karimi, MA, Hodjat, M, Chiniforush, N et al.. The photobiomodulation effects of continuous and pulsed blue diode laser on proliferation and osteogenic differentiation of periodontal ligament stem cells. Photochem Photobiol. 2025; :. doi: 10.1111/php.14104. PubMed PMID:40251753 .
- Ding, Y, Ran, Y. OGA promotes human dental pulp stem cell senescence and inhibits mitophagy by inhibition of O-GlcNAcylation of KLF2. BMC Oral Health. 2025;25 (1):595. doi: 10.1186/s12903-025-05927-1. PubMed PMID:40251583 PubMed Central PMC12008942.
- Raik, S, Kaur, B, Kumar, S, Rattan, V, Kumar, N, Bhattacharyya, S et al.. Secretome Derived From Mesenchymal Stem Cells Cultured as Monolayer Show Enhanced Bone Regeneration Compared to Secretome From 3D Spheroid - Clues From the Proteome. Adv Healthc Mater. 2025; :e2500885. doi: 10.1002/adhm.202500885. PubMed PMID:40249147 .
- Liu, Y, Peng, Y, Chen, L, Xiang, Y, Zhang, X, Song, J et al.. Single-cell sequencing systematically analyzed the mechanism of Emdogain on the restoration of delayed replantation periodontal membrane. Int J Oral Sci. 2025;17 (1):33. doi: 10.1038/s41368-024-00345-5. PubMed PMID:40246878 PubMed Central PMC12006293.
- Wang, X, Wang, L, Zhou, L, Chen, L, Shi, J, Ge, J et al.. NUP62 alleviates senescence and promotes the stemness of human dental pulp stem cells via NSD2-dependent epigenetic reprogramming. Int J Oral Sci. 2025;17 (1):34. doi: 10.1038/s41368-025-00362-y. PubMed PMID:40246825 PubMed Central PMC12006529.
- Soe, ZC, Nan, DN, Wahyudi, R, Vongsutilers, V, Kamolratanakul, P, Everts, V et al.. Asiaticoside-Loaded Nanosponges Hydrogel Has an Anti-inflammatory Effect and Promotes Human Dental Pulp Regeneration. J Endod. 2025; :. doi: 10.1016/j.joen.2025.04.004. PubMed PMID:40246141 .
- Hajialigol, A, Azizi, G, Seifi Alan, M, Soltani, A, Arabian, Z, Tamiji, M et al.. Dominant-Negative Versus Gain-of-Function STAT3 Defects: A Systematic Review on Epidemiological, Clinical, Immunological, and Molecular Aspects. J Allergy Clin Immunol Pract. 2025; :. doi: 10.1016/j.jaip.2025.04.014. PubMed PMID:40246075 .
- Fernández-Pérez, AG, Herrera-González, A, López-Naranjo, EJ, Martínez-Álvarez, IA, Uribe-Rodríguez, D, Ramírez-Arreola, DE et al.. Extracellular Vesicles from Different Mesenchymal Stem Cell Types Exhibit Distinctive Surface Protein Profiling and Molecular Characteristics: A Comparative Analysis. Int J Mol Sci. 2025;26 (7):. doi: 10.3390/ijms26073393. PubMed PMID:40244251 PubMed Central PMC11989379.
- Musílková, J, Beran, M, Sedlář, A, Slepička, P, Bartoš, M, Kolská, Z et al.. Composite Polylactide/Polycaprolactone Foams with Hierarchical Porous Structure for Pre-Vascularized Tissue Engineering. Int J Mol Sci. 2025;26 (7):. doi: 10.3390/ijms26072974. PubMed PMID:40243624 PubMed Central PMC11988939.
- Palazzo, E, Lotti, R, Quadri, M, Pincelli, C, Marconi, A. IL-17 Ligand and Receptor Family Members Are Differentially Expressed by Keratinocyte Subpopulations and Modulate Their Differentiation and Inflammatory Phenotype. Int J Mol Sci. 2025;26 (7):. doi: 10.3390/ijms26072989. PubMed PMID:40243580 PubMed Central PMC11988555.
- Srimaneepong, V, Trachoo, V, Phothichailert, S, Srithanyarat, SS, Mahanonda, R, Norbert, H et al.. Evaluating Surface Properties and Cellular Responses to Surface-Treated Different Triple Periodic Minimal Surface L-PBF Ti6Al4V Lattices for Biomedical Devices. Int J Mol Sci. 2025;26 (7):. doi: 10.3390/ijms26072960. PubMed PMID:40243578 PubMed Central PMC11988758.
- Yang, H, Yuan, F, Song, J, Huang, Y, Shan, Z, Fan, Z et al.. m6A-Modified GATA2 Enhances Odontogenic Differentiation in Stem Cells from the Apical Papilla. Int J Mol Sci. 2025;26 (7):. doi: 10.3390/ijms26072920. PubMed PMID:40243520 PubMed Central PMC11988903.
- Lin, TY, Mishra, VK, Dubey, R, Chaturvedi, TP, Narayan, SA, Fang, HW et al.. Transcriptomic analysis reveals distinct molecular signatures and regulatory networks of osteoarthritic chondrocytes versus mesenchymal stem cells during chondrogenesis. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2025; :. doi: 10.5507/bp.2025.008. PubMed PMID:40242907 .
- Del Vecchio, V, Sanchez-Pajares, IR, Panda, SK, Rehman, A, De Falco, V, Nigam, A et al.. Xanthohumol modulate autophagy and ER stress to counteract stemness and enhance cisplatin efficacy in head and neck squamous cell carcinoma. Sci Rep. 2025;15 (1):13137. doi: 10.1038/s41598-025-98003-1. PubMed PMID:40240816 PubMed Central PMC12003764.
- Kandettu, A, Ghosal, J, Tharayil, JS, Kuthethur, R, Mallya, S, Narasimhamurthy, RK et al.. Inhibition of mitochondrial genome-encoded mitomiR-3 contributes to ZEB1 mediated GPX4 downregulation and pro-ferroptotic lipid metabolism to induce ferroptosis in breast cancer cells. Free Radic Biol Med. 2025;234 :151-168. doi: 10.1016/j.freeradbiomed.2025.04.019. PubMed PMID:40239722 .
- Manokawinchoke, J, Limraksasin, P, Limjeerajarus, CN, Limjeerajarus, N, Samaranayake, LP, Egusa, H et al.. Mechanical Force Induces Osteogenic Differentiation of Murine Induced Pluripotent Stem Cells via TGF-β Signalling. Orthod Craniofac Res. 2025; :. doi: 10.1111/ocr.12933. PubMed PMID:40238110 .
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