Dental Stem Cells

The Mesenchymal Stem Cells found in Teeth are now the most researched Stem Cells in the Scientific Literature.

Dental Stem Cell Research

  1. Almansoori, AA, Kwon, OJ, Nam, JH, Seo, YK, Song, HR, Lee, JH et al.. Mesenchymal stem cells and platelet-rich plasma-impregnated polycaprolactone-β tricalcium phosphate bio-scaffold enhanced bone regeneration around dental implants. Int J Implant Dent. 2021;7 (1):35. doi: 10.1186/s40729-021-00317-y. PubMed PMID:33948811 .
  2. Sordi, MB, Cruz, A, Fredel, MC, Magini, R, Sharpe, PT. Three-dimensional bioactive hydrogel-based scaffolds for bone regeneration in implant dentistry. Mater Sci Eng C Mater Biol Appl. 2021;124 :112055. doi: 10.1016/j.msec.2021.112055. PubMed PMID:33947549 .
  3. Dai, J, Fu, Y, Chen, D, Sun, Z. A novel and injectable strontium-containing hydroxyapatite bone cement for bone substitution: A systematic evaluation. Mater Sci Eng C Mater Biol Appl. 2021;124 :112052. doi: 10.1016/j.msec.2021.112052. PubMed PMID:33947546 .
  4. Falini, B, Sportoletti, P, Sorcini, D. BCOR gene alterations in hematological diseases. Blood. 2021; :. doi: 10.1182/blood.2021010958. PubMed PMID:33945606 .
  5. Koyanagi-Matsumura, E, Miura, H, Saito, M, Harada, S. Type II/III cell composition and NCAM expression in taste buds. Cell Tissue Res. 2021; :. doi: 10.1007/s00441-021-03452-5. PubMed PMID:33942154 .
  6. Yi, B, Ding, T, Jiang, S, Gong, T, Chopra, H, Sha, O et al.. Conversion of stem cells from apical papilla into endothelial cells by small molecules and growth factors. Stem Cell Res Ther. 2021;12 (1):266. doi: 10.1186/s13287-021-02350-5. PubMed PMID:33941255 .
  7. Osmond, M, Krebs, MD. Tunable Chitosan-Calcium Phosphate Composites as Cell-Instructive Dental Pulp Capping Agents. J Biomater Sci Polym Ed. 2021; :1-13. doi: 10.1080/09205063.2021.1925390. PubMed PMID:33941040 .
  8. Galvan, ML, Paradise, CR, Kubrova, E, Jerez, S, Khani, F, Thaler, R et al.. Multiple pharmacological inhibitors targeting the epigenetic suppressor enhancer of Zeste homolog 2 (EZH2) accelerate osteoblast differentiation. Bone. 2021; :115993. doi: 10.1016/j.bone.2021.115993. PubMed PMID:33940225 .
  9. Effendi, MC, Taufiq, A, Bachtiar, BM, Bachtiar, EW, Herda, E. The role of NMT induction on odontogenic proliferation and differentiation of dental pulp stem cells. Heliyon. 2021;7 (4):e06598. doi: 10.1016/j.heliyon.2021.e06598. PubMed PMID:33937538 PubMed Central PMC8079446.
  10. Santoprete, S, Marchetti, F, Rubino, C, Bedini, MG, Nasto, LA, Cipolloni, V et al.. Fresh autologous stromal tissue fraction for the treatment of knee osteoarthritis related pain and disability. Orthop Rev (Pavia). 2021;13 (1):9161. doi: 10.4081/or.2021.9161. PubMed PMID:33936575 PubMed Central PMC8082170.
  11. Huang, X, Qiu, W, Pan, Y, Li, J, Chen, Z, Zhang, K et al.. Exosomes from LPS-Stimulated hDPSCs Activated the Angiogenic Potential of HUVECs In Vitro. Stem Cells Int. 2021;2021 :6685307. doi: 10.1155/2021/6685307. PubMed PMID:33936213 PubMed Central PMC8062194.
  12. Kim, D, Lee, AE, Xu, Q, Zhang, Q, Le, AD. Gingiva-Derived Mesenchymal Stem Cells: Potential Application in Tissue Engineering and Regenerative Medicine - A Comprehensive Review. Front Immunol. 2021;12 :667221. doi: 10.3389/fimmu.2021.667221. PubMed PMID:33936109 PubMed Central PMC8085523.
  13. Chae, DS, Han, S, Lee, MK, Kim, SW. Genome Edited Sirt1-Overexpressing Human Mesenchymal Stem Cells Exhibit Therapeutic Effects in Treating Collagen-Induced Arthritis. Mol Cells. 2021;44 (4):245-253. doi: 10.14348/molcells.2021.0037. PubMed PMID:33935044 .
  14. Jauković, A, Kukolj, T, Trivanović, D, Okić-Đorđević, I, Obradović, H, Miletić, M et al.. Modulating stemness of mesenchymal stem cells from exfoliated deciduous and permanent teeth by IL-17 and bFGF. J Cell Physiol. 2021; :. doi: 10.1002/jcp.30399. PubMed PMID:33934350 .
  15. Li, PL, Wang, YX, Zhao, ZD, Li, ZL, Liang, JW, Wang, Q et al.. Clinical-grade human dental pulp stem cells suppressed the activation of osteoarthritic macrophages and attenuated cartilaginous damage in a rabbit osteoarthritis model. Stem Cell Res Ther. 2021;12 (1):260. doi: 10.1186/s13287-021-02353-2. PubMed PMID:33933140 .
  16. Sarra, G, Machado, MEL, Caballero-Flores, HV, Moreira, MS, Pedroni, ACF, Marques, MM et al.. Effect of human dental pulp stem cell conditioned medium in the dentin-pulp complex regeneration: A pilot in vivo study. Tissue Cell. 2021;72 :101536. doi: 10.1016/j.tice.2021.101536. PubMed PMID:33932880 .
  17. Pethe, P, Kale, V. Placenta: A gold mine for translational research and regenerative medicine. Reprod Biol. 2021;21 (2):100508. doi: 10.1016/j.repbio.2021.100508. PubMed PMID:33930790 .
  18. Carlomagno, C, Giannasi, C, Niada, S, Bedoni, M, Gualerzi, A, Brini, AT et al.. Raman Fingerprint of Extracellular Vesicles and Conditioned Media for the Reproducibility Assessment of Cell-Free Therapeutics. Front Bioeng Biotechnol. 2021;9 :640617. doi: 10.3389/fbioe.2021.640617. PubMed PMID:33928071 PubMed Central PMC8076682.
  19. Qu, G, Li, Y, Chen, L, Chen, Q, Zou, D, Yang, C et al.. Comparison of Osteogenic Differentiation Potential of Human Dental-Derived Stem Cells Isolated from Dental Pulp, Periodontal Ligament, Dental Follicle, and Alveolar Bone. Stem Cells Int. 2021;2021 :6631905. doi: 10.1155/2021/6631905. PubMed PMID:33927769 PubMed Central PMC8049831.
  20. Choy, CS, Lee, WF, Lin, PY, Wu, YF, Huang, HM, Teng, NC et al.. Surface Modified β-Tricalcium phosphate enhanced stem cell osteogenic differentiation in vitro and bone regeneration in vivo. Sci Rep. 2021;11 (1):9234. doi: 10.1038/s41598-021-88402-5. PubMed PMID:33927241 PubMed Central PMC8084957.
  21. Tan, YZ, Xu, XY, Dai, JM, Yin, Y, He, XT, Zhang, YL et al.. Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process. Stem Cell Res Ther. 2021;12 (1):254. doi: 10.1186/s13287-021-02322-9. PubMed PMID:33926537 PubMed Central PMC8082824.
  22. Matsuzawa, A, Lee, J, Nakagawa, S, Itoh, J, Takahashi Ueda, M, Mitsuhashi, S et al.. HERV-Derived Ervpb1 Is Conserved in Simiiformes, Exhibiting Expression in Hematopoietic Cell Lineages Including Macrophages. Int J Mol Sci. 2021;22 (9):. doi: 10.3390/ijms22094504. PubMed PMID:33925887 .
  23. Afami, ME, El Karim, I, About, I, Coulter, SM, Laverty, G, Lundy, FT et al.. Ultrashort Peptide Hydrogels Display Antimicrobial Activity and Enhance Angiogenic Growth Factor Release by Dental Pulp Stem/Stromal Cells. Materials (Basel). 2021;14 (9):. doi: 10.3390/ma14092237. PubMed PMID:33925337 .
  24. Bhandi, S, Alkahtani, A, Reda, R, Mashyakhy, M, Boreak, N, Maganur, PC et al.. Parathyroid Hormone Secretion and Receptor Expression Determine the Age-Related Degree of Osteogenic Differentiation in Dental Pulp Stem Cells. J Pers Med. 2021;11 (5):. doi: 10.3390/jpm11050349. PubMed PMID:33925324 .
  25. Donsante, S, Palmisano, B, Serafini, M, Robey, PG, Corsi, A, Riminucci, M et al.. From Stem Cells to Bone-Forming Cells. Int J Mol Sci. 2021;22 (8):. doi: 10.3390/ijms22083989. PubMed PMID:33924333 PubMed Central PMC8070464.
  26. Jeon, HH, Teixeira, H, Tsai, A. Mechanistic Insight into Orthodontic Tooth Movement Based on Animal Studies: A Critical Review. J Clin Med. 2021;10 (8):. doi: 10.3390/jcm10081733. PubMed PMID:33923725 PubMed Central PMC8072633.
  27. Iezzi, G, Scarano, A, Valbonetti, L, Mazzoni, S, Furlani, M, Mangano, C et al.. Biphasic Calcium Phosphate Biomaterials: Stem Cell-Derived Osteoinduction or In Vivo Osteoconduction? Novel Insights in Maxillary Sinus Augmentation by Advanced Imaging. Materials (Basel). 2021;14 (9):. doi: 10.3390/ma14092159. PubMed PMID:33922799 .
  28. Pilbauerova, N, Schmidt, J, Soukup, T, Koberova Ivancakova, R, Suchanek, J. The Effects of Cryogenic Storage on Human Dental Pulp Stem Cells. Int J Mol Sci. 2021;22 (9):. doi: 10.3390/ijms22094432. PubMed PMID:33922674 .
  29. Kim, SG. A Cell-Based Approach to Dental Pulp Regeneration Using Mesenchymal Stem Cells: A Scoping Review. Int J Mol Sci. 2021;22 (9):. doi: 10.3390/ijms22094357. PubMed PMID:33921924 .
  30. Han, J, Jeong, W, Kim, MK, Nam, SH, Park, EK, Kang, HW et al.. Demineralized Dentin Matrix Particle-Based Bio-Ink for Patient-Specific Shaped 3D Dental Tissue Regeneration. Polymers (Basel). 2021;13 (8):. doi: 10.3390/polym13081294. PubMed PMID:33921045 PubMed Central PMC8071469.
  31. Inchingolo, AD, Inchingolo, AM, Bordea, IR, Malcangi, G, Xhajanka, E, Scarano, A et al.. SARS-CoV-2 Disease through Viral Genomic and Receptor Implications: An Overview of Diagnostic and Immunology Breakthroughs. Microorganisms. 2021;9 (4):. doi: 10.3390/microorganisms9040793. PubMed PMID:33920179 PubMed Central PMC8070527.
  32. Bari, E, Roato, I, Perale, G, Rossi, F, Genova, T, Mussano, F et al.. Biohybrid Bovine Bone Matrix for Controlled Release of Mesenchymal Stem/Stromal Cell Lyosecretome: A Device for Bone Regeneration. Int J Mol Sci. 2021;22 (8):. doi: 10.3390/ijms22084064. PubMed PMID:33920046 PubMed Central PMC8071018.
  33. Posa, F, Colaianni, G, Di Cosola, M, Dicarlo, M, Gaccione, F, Colucci, S et al.. The Myokine Irisin Promotes Osteogenic Differentiation of Dental Bud-Derived MSCs. Biology (Basel). 2021;10 (4):. doi: 10.3390/biology10040295. PubMed PMID:33916859 PubMed Central PMC8065887.
  34. Sato, S, Shimizu, E, He, J, Ogawa, M, Asai, K, Yazu, H et al.. Positive Effects of Oral Antibiotic Administration in Murine Chronic Graft-Versus-Host Disease. Int J Mol Sci. 2021;22 (7):. doi: 10.3390/ijms22073745. PubMed PMID:33916809 PubMed Central PMC8038334.
  35. Rosales-Ibáñez, R, Cubo-Mateo, N, Rodríguez-Navarrete, A, González-González, AM, Villamar-Duque, TE, Flores-Sánchez, LO et al.. Assessment of a PCL-3D Printing-Dental Pulp Stem Cells Triplet for Bone Engineering: An In Vitro Study. Polymers (Basel). 2021;13 (7):. doi: 10.3390/polym13071154. PubMed PMID:33916576 PubMed Central PMC8038447.
  36. Breunig, M, Merkle, J, Wagner, M, Melzer, MK, Barth, TFE, Engleitner, T et al.. Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells. Cell Stem Cell. 2021; :. doi: 10.1016/j.stem.2021.03.005. PubMed PMID:33915078 .
  37. Habara, O, Logan, CY, Kanai-Azuma, M, Nusse, R, Takase, HM. WNT signaling in pre-granulosa cells is required for ovarian folliculogenesis and female fertility. Development. 2021;148 (9):. doi: 10.1242/dev.198846. PubMed PMID:33914868 .
  38. Katata, C, Sasaki, JI, Li, A, Abe, GL, Nör, JE, Hayashi, M et al.. Fabrication of Vascularized DPSC Constructs for Efficient Pulp Regeneration. J Dent Res. 2021; :220345211007427. doi: 10.1177/00220345211007427. PubMed PMID:33913364 .
  39. Zhu, Y, Wei, SM, Yan, KX, Gu, YX, Lai, HC, Qiao, SC et al.. Bovine-Derived Xenografts Immobilized With Cryopreserved Stem Cells From Human Adipose and Dental Pulp Tissues Promote Bone Regeneration: A Radiographic and Histological Study. Front Bioeng Biotechnol. 2021;9 :646690. doi: 10.3389/fbioe.2021.646690. PubMed PMID:33912548 PubMed Central PMC8075412.
  40. Gupta, AA, Kheur, S, Badhe, RV, Raj, AT, Bhonde, R, Jaisinghani, A et al.. Assessing the potential use of chitosan scaffolds for the sustained localized delivery of vitamin D. Saudi J Biol Sci. 2021;28 (4):2210-2215. doi: 10.1016/j.sjbs.2021.01.008. PubMed PMID:33911937 PubMed Central PMC8071810.
  41. Chen, H, Dai, Y, Cui, J, Yin, X, Feng, W, Lv, M et al.. Carbon Monoxide Releasing Molecule-3 Enhances Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Carbon Monoxide Release. Drug Des Devel Ther. 2021;15 :1691-1704. doi: 10.2147/DDDT.S300356. PubMed PMID:33911854 PubMed Central PMC8075314.
  42. Parmar, A, Ansari, NA, Parmar, G, Krishnakumar, A. Evaluation of cell viability of Human Dental Pulp Stem Cells in Two dimensional and Three dimensional Fibrin Glue Scaffold. J Conserv Dent. ;23 (5):479-483. doi: 10.4103/JCD.JCD_439_20. PubMed PMID:33911357 PubMed Central PMC8066662.
  43. Nifosì, G, Nifosì, L, Nifosì, AF. Mesenchymal stem cells in the treatment of osteonecrosis of the jaw. J Korean Assoc Oral Maxillofac Surg. 2021;47 (2):65-75. doi: 10.5125/jkaoms.2021.47.2.65. PubMed PMID:33911038 .
  44. Kushiro, H, Takahashi, H, Tanaka, A. Effects of the prevention of medication-related osteonecrosis of the jaw by local administration of a dental pulp stem cell-conditioned medium to the rat tooth extraction socket. Odontology. 2021; :. doi: 10.1007/s10266-021-00607-2. PubMed PMID:33907964 .
  45. Rodriguez, UA, Socorro, M, Criscimanna, A, Martins, CP, Mohamed, N, Hu, J et al.. Alpha to beta cell conversion in the postpartum mouse pancreas involves lgr5 progeny. Diabetes. 2021; :. doi: 10.2337/db20-1059. PubMed PMID:33906911 .
  46. Manaspon, C, Jongwannasiri, C, Chumprasert, S, Sa-Ard-Iam, N, Mahanonda, R, Pavasant, P et al.. Human dental pulp stem cell responses to different dental pulp capping materials. BMC Oral Health. 2021;21 (1):209. doi: 10.1186/s12903-021-01544-w. PubMed PMID:33902558 PubMed Central PMC8074430.
  47. Kent, I, Jahansouz, C, Ghuman, A, Shpitz, B, Kidron, D, Yaffe, V et al.. Human Oral Mucosal Stem Cells Reduce Anastomotic Leak in an Animal Model of Colonic Surgery. Eur Surg Res. 2021; :1-8. doi: 10.1159/000514987. PubMed PMID:33902028 .
  48. Li, H, Ma, B, Yang, H, Qiao, J, Tian, W, Yu, R et al.. Xenogeneic dentin matrix as a scaffold for biomineralization and induced odontogenesis. Biomed Mater. 2021; :. doi: 10.1088/1748-605X/abfbbe. PubMed PMID:33902010 .
  49. Ma, R, Li, X, Tewari, N, Liu, Y, Bhawal, UK, Zeng, X et al.. microRNA-21 ameliorates the impairment of autophagy in palatal wound healing. J Physiol Pharmacol. 2020;71 (6):. doi: 10.26402/jpp.2020.6.14. PubMed PMID:33902001 .
  50. Das, M, Das, A, Barui, A, Paul, RR. Comparative evaluation of proliferative potential and replicative senescence associated changes in mesenchymal stem cells derived from dental pulp and umbilical cord. Cell Tissue Bank. 2021; :. doi: 10.1007/s10561-021-09926-8. PubMed PMID:33900487 .
  51. Lu, Y, Yu, CH, Yang, G, Sun, N, Jiang, F, Zhou, M et al.. A rapidly magnetically assembled stem cell microtissue with "hamburger" architecture and enhanced vascularization capacity. Bioact Mater. 2021;6 (11):3756-3765. doi: 10.1016/j.bioactmat.2021.03.007. PubMed PMID:33898876 PubMed Central PMC8044908.
  52. Li, B, He, X, Dong, Z, Xuan, K, Sun, W, Gao, L et al.. Ionomycin ameliorates hypophosphatasia via rescuing alkaline phosphatase deficiency-mediated L-type Ca2+ channel internalization in mesenchymal stem cells. Bone Res. 2020;8 (1):19. doi: 10.1038/s41413-020-0090-7. PubMed PMID:33896936 .
  53. Lin, Z, Tang, X, Wan, J, Zhang, X, Liu, C, Liu, T et al.. Functions and mechanisms of circular RNAs in regulating stem cell differentiation. RNA Biol. 2021; :1-14. doi: 10.1080/15476286.2021.1913551. PubMed PMID:33896374 .
  54. Johanson, Z, Manzanares, E, Underwood, C, Clark, B, Fernandez, V, Smith, M et al.. Ontogenetic development of the holocephalan dentition: Morphological transitions of dentine in the absence of teeth. J Anat. 2021; :. doi: 10.1111/joa.13445. PubMed PMID:33895988 .
  55. Wong, MM, Chan, HY, Aziz, NA, Ramasamy, TS, Bong, JJ, Ch'ng, ES et al.. Interplay of autophagy and cancer stem cells in hepatocellular carcinoma. Mol Biol Rep. 2021; :. doi: 10.1007/s11033-021-06334-9. PubMed PMID:33893928 .
  56. Chan, YH, Lee, YC, Hung, CY, Yang, PJ, Lai, PC, Feng, SW et al.. Three-dimensional Spheroid Culture Enhances Multipotent Differentiation and Stemness Capacities of Human Dental Pulp-derived Mesenchymal Stem Cells by Modulating MAPK and NF-kB Signaling Pathways. Stem Cell Rev Rep. 2021; :. doi: 10.1007/s12015-021-10172-4. PubMed PMID:33893620 .
  57. Oubenyahya, H. Stem Cells from Dental Pulp of Human Exfoliated Teeth: Current Understanding and Future Challenges in Dental Tissue Engineering. Chin J Dent Res. 2021;24 (1):9-20. doi: 10.3290/j.cjdr.b1105867. PubMed PMID:33890451 .
  58. Xu, X, Liang, C, Gao, X, Huang, H, Xing, X, Tang, Q et al.. Adipose Tissue-derived Microvascular Fragments as Vascularization Units for Dental Pulp Regeneration. J Endod. 2021; :. doi: 10.1016/j.joen.2021.04.012. PubMed PMID:33887305 .
  59. Yan, Y, Zhou, P, Lu, H, Guan, Y, Ma, M, Wang, J et al.. Potential apply of hydrogel-carried chlorhexidine and metronidazole in root canal disinfection. Dent Mater J. 2021; :. doi: 10.4012/dmj.2020-299. PubMed PMID:33883328 .
  60. Babaye Abdollahi, B, Malekzadeh, R, Pournaghi Azar, F, Salehnia, F, Naseri, AR, Ghorbani, M et al.. Main Approaches to Enhance Radiosensitization in Cancer Cells by Nanoparticles: A Systematic Review. Adv Pharm Bull. 2021;11 (2):212-223. doi: 10.34172/apb.2021.025. PubMed PMID:33880343 PubMed Central PMC8046397.
  61. Birant, S, Duran, Y, Gokalp, M, Akkoc, T, Seymen, F. Effects of different detergent-containing children's toothpastes on the viability, osteogenic and chondrogenic differentiation of human dental periodontal ligament stem cells and gingival stem cells in vitro. Tissue Cell. 2021;72 :101538. doi: 10.1016/j.tice.2021.101538. PubMed PMID:33878638 .
  62. Liu, Y, Wu, J, Zhang, H, Wu, Y, Tang, C. Covalent immobilization of the phytic acid-magnesium layer on titanium improves the osteogenic and antibacterial properties. Colloids Surf B Biointerfaces. 2021;203 :111768. doi: 10.1016/j.colsurfb.2021.111768. PubMed PMID:33872830 .
  63. Liu, C, Yang, G, Zhou, M, Zhang, X, Wu, X, Wu, P et al.. Magnesium Ammonium Phosphate Composite Cell-Laden Hydrogel Promotes Osteogenesis and Angiogenesis In Vitro. ACS Omega. 2021;6 (14):9449-9459. doi: 10.1021/acsomega.0c06083. PubMed PMID:33869925 PubMed Central PMC8047646.
  64. Komabashiri, N, Suehiro, F, Ishii, M, Nishimura, M. Efficacy of chitinase-3-like protein 1 as an in vivo bone formation predictable marker of maxillary/mandibular bone marrow stromal cells. Regen Ther. 2021;18 :38-50. doi: 10.1016/j.reth.2021.03.004. PubMed PMID:33869686 PubMed Central PMC8027134.
  65. Albashari, AA, He, Y, Albaadani, MA, Xiang, Y, Ali, J, Hu, F et al.. Titanium Nanotube Modified With Silver Cross-Linked Basic Fibroblast Growth Factor Improves Osteoblastic Activities of Dental Pulp Stem Cells and Antibacterial Effect. Front Cell Dev Biol. 2021;9 :654654. doi: 10.3389/fcell.2021.654654. PubMed PMID:33869214 PubMed Central PMC8047219.
  66. Xi, X, Zhao, Y, Liu, H, Li, Z, Chen, S, Liu, D et al.. Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch. Exp Cell Res. 2021;403 (2):112598. doi: 10.1016/j.yexcr.2021.112598. PubMed PMID:33865812 .
  67. Held, T, Herpel, C, Schwindling, FS, Christ, L, Lang, K, Regnery, S et al.. 3D-printed individualized tooth-borne tissue retraction devices compared to conventional dental splints for head and neck cancer radiotherapy: a randomized controlled trial. Radiat Oncol. 2021;16 (1):75. doi: 10.1186/s13014-021-01803-8. PubMed PMID:33865401 PubMed Central PMC8052727.
  68. Kinsella, FA, Inman, CF, Croft, W, Zuo, J, Pearce, H, Barbieri, S et al.. CD52/GPI- T-Cells Are Enriched for Alloreactive Specificity and Predict Acute Graft-Versus-Host-Disease After Stem Cell Transplantation. Transplant Cell Ther. 2021; :. doi: 10.1016/j.jtct.2021.02.023. PubMed PMID:33863699 .
  69. Fujisaki, S, Kajiya, H, Yanagi, T, Maeshiba, M, Kakura, K, Kido, H et al.. Enhancement of jaw bone regeneration via ERK1/2 activation using dedifferentiated fat cells. Cytotherapy. 2021; :. doi: 10.1016/j.jcyt.2021.02.115. PubMed PMID:33863640 .
  70. Hassan, MG, Zaher, AR, Athanasiou, AE. How orthodontic research can be enriched and advanced by the novel and promising evolutions in biomedicine. J Orthod. 2021; :14653125211006116. doi: 10.1177/14653125211006116. PubMed PMID:33860691 .
  71. Deng, Z, Yan, W, Dai, X, Chen, M, Qu, Q, Wu, B et al.. N-Cadherin Regulates the Odontogenic Differentiation of Dental Pulp Stem Cells via β-Catenin Activity. Front Cell Dev Biol. 2021;9 :661116. doi: 10.3389/fcell.2021.661116. PubMed PMID:33859987 PubMed Central PMC8042212.
  72. Xu, R, Shen, X, Xie, H, Zhang, H, Liu, D, Chen, X et al.. Identification of the canonical and noncanonical role of miR-143/145 in estrogen-deficient bone loss. Theranostics. 2021;11 (11):5491-5510. doi: 10.7150/thno.55041. PubMed PMID:33859759 PubMed Central PMC8039936.
  73. Zheng, A, Wang, X, Wang, J, Xin, X, Yu, Y, Liu, Y et al.. Synergistic effect between 2-N,6-O-sulfonated chitosan and bone morphogenetic protein-2. Carbohydr Polym. 2021;263 :117888. doi: 10.1016/j.carbpol.2021.117888. PubMed PMID:33858564 .
  74. Li, C, Duan, G, Feng, Y. Downregulation of miR-184 facilitates osseous differentiation in periodontal ligament stem cells by modulating nuclear factor I-C. J Dent Sci. 2021;16 (2):668-675. doi: 10.1016/j.jds.2020.09.011. PubMed PMID:33854717 PubMed Central PMC8025194.
  75. Huang, YW, Lin, CY, Chin, YT, Kuo, PJ, Wu, Y, Weng, IT et al.. 2,3,5,4'-tetrahydroxystilbene-2-O-b-D-glucoside triggers the pluripotent-like possibility of dental pulp stem cells by activating the JAK2/STAT3 axis: Preliminary observations. J Dent Sci. 2021;16 (2):599-607. doi: 10.1016/j.jds.2020.10.011. PubMed PMID:33854708 PubMed Central PMC8025197.
  76. Chin, YT, Liu, CM, Chen, TY, Chung, YY, Lin, CY, Hsiung, CN et al.. 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside-stimulated dental pulp stem cells-derived conditioned medium enhances cell activity and anti-inflammation. J Dent Sci. 2021;16 (2):586-598. doi: 10.1016/j.jds.2020.10.014. PubMed PMID:33854707 PubMed Central PMC8025232.
  77. Imanishi, Y, Hata, M, Matsukawa, R, Aoyagi, A, Omi, M, Mizutani, M et al.. Efficacy of extracellular vesicles from dental pulp stem cells for bone regeneration in rat calvarial bone defects. Inflamm Regen. 2021;41 (1):12. doi: 10.1186/s41232-021-00163-w. PubMed PMID:33853679 PubMed Central PMC8048358.
  78. Pieles, O, Reichert, TE, Morsczeck, C. Classical isoforms of protein kinase C (PKC) and Akt regulate the osteogenic differentiation of human dental follicle cells via both β-catenin and NF-κB. Stem Cell Res Ther. 2021;12 (1):242. doi: 10.1186/s13287-021-02313-w. PubMed PMID:33853677 PubMed Central PMC8048169.
  79. Yang, J, Toda Nakamura, M, Hallett, SA, Ueharu, H, Zhang, H, Kelley, K et al.. Generation of a new mouse line with conditionally activated signaling through the BMP receptor, ACVR1: A tool to characterize pleiotropic roles of BMP functions. Genesis. 2021; :e23419. doi: 10.1002/dvg.23419. PubMed PMID:33851764 .
  80. Alhazzazi, TY, Alghamdi, FT. Clinical applications of dental stem cells in modern regenerative medicine: A systematic review with updates. Niger J Clin Pract. 2021;24 (4):457-463. doi: 10.4103/njcp.njcp_498_20. PubMed PMID:33851664 .
  81. Chen, Q, Yuan, C, Jiang, S, Heng, BC, Zou, T, Shen, Z et al.. Small molecules efficiently reprogram apical papilla stem cells into neuron-like cells. Exp Ther Med. 2021;21 (6):546. doi: 10.3892/etm.2021.9978. PubMed PMID:33850518 PubMed Central PMC8027758.
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