Dental Stem Cells

The Mesenchymal Stem Cells found in Teeth are now the most researched Stem Cells in the Scientific Literature.

Dental Stem Cell Research

  1. Morita, K, Nakamura, A, Machida, M, Kawasaki, T, Nakanishi, R, Ichida, J et al.. Efficient reprogramming of human fibroblasts using RNA reprogramming with DAPT and iDOT1L under normoxia conditions. Regen Ther. 2022;21 :389-397. doi: 10.1016/j.reth.2022.09.002. PubMed PMID:36196449 PubMed Central PMC9493288.
  2. Li, J, Du, H, Ji, X, Chen, Y, Li, Y, Heng, BC et al.. ETV2 promotes osteogenic differentiation of human dental pulp stem cells through the ERK/MAPK and PI3K-Akt signaling pathways. Stem Cell Res Ther. 2022;13 (1):495. doi: 10.1186/s13287-022-03052-2. PubMed PMID:36195958 .
  3. Hatori, A, Fujii, Y, Kawase-Koga, Y, Ogasawara, T, Chikira, J, Minami, S et al.. VCAM-1 and GFPT-2: Predictive markers of osteoblast differentiation in human dental pulp stem cells. Bone. 2022; :116575. doi: 10.1016/j.bone.2022.116575. PubMed PMID:36195245 .
  4. Wang, Y, Zhu, G, Pei, F, Wang, Y, Liu, J, Lu, C et al.. RNA-Sequence Reveals the Regulatory Mechanism of miR-149 on Osteoblast Skeleton under Mechanical Tension. Stem Cells Int. 2022;2022 :9640878. doi: 10.1155/2022/9640878. PubMed PMID:36193254 PubMed Central PMC9525771.
  5. Brizuela, C, Huang, GT, Diogenes, A, Botero, T, Khoury, M. The Four Pillars for Successful Regenerative Therapy in Endodontics: Stem Cells, Biomaterials, Growth Factors, and Their Synergistic Interactions. Stem Cells Int. 2022;2022 :1580842. doi: 10.1155/2022/1580842. PubMed PMID:36193253 PubMed Central PMC9526564.
  6. He, F, Li, J, Wang, Y, Li, Z, Wang, L, Li, Y et al.. Design of Cefotaxime Sodium-Loaded Polydopamine Coatings with Controlled Surface Roughness for Titanium Implants. ACS Biomater Sci Eng. 2022; :. doi: 10.1021/acsbiomaterials.2c00702. PubMed PMID:36191062 .
  7. Mojtahedi, H, Hossein-Khannazer, N, Mahmoud Hashemi, S, Masoudnia, M, Askarzadeh, M, Khojasteh, A et al.. Effects of Lipopolysaccharide from Porphyromonas gingivalis and Escherichia coli on Gene Expression Levels of Toll-like Receptors and Inflammatory Cytokines in Human Dental Pulp Stem Cells. Iran J Immunol. 2022;19 (3):299-310. doi: 10.22034/iji.2022.92223.2136. PubMed PMID:36190383 .
  8. Gopinath, VK, Mohammad, MG, Sheela, S. Immunomodulatory effect of IL-1RA in LPS activated macrophage/dental pulp stem cells co-culture. Int Endod J. 2022; :. doi: 10.1111/iej.13839. PubMed PMID:36190353 .
  9. Kalafati, L, Hatzioannou, A, Hajishengallis, G, Chavakis, T. The role of neutrophils in trained immunity. Immunol Rev. 2022; :. doi: 10.1111/imr.13142. PubMed PMID:36190144 .
  10. Sheykhhasan, M, Qomi, RT, Kalhor, N, Mehdizadeh, M, Ghiasi, M. Retraction Note to: Evaluation of the Ability of Natural and Synthetic Scaffolds in Providing an Appropriate Environment for Growth and Chondrogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells. Indian J Orthop. 2022;56 (10):1841. doi: 10.1007/s43465-022-00738-w. PubMed PMID:36187583 PubMed Central PMC9485379.
  11. Xiong, W, Liu, Y, Zhou, H, Jing, S, He, Y, Ye, Q et al.. Alzheimer's disease: Pathophysiology and dental pulp stem cells therapeutic prospects. Front Cell Dev Biol. 2022;10 :999024. doi: 10.3389/fcell.2022.999024. PubMed PMID:36187488 PubMed Central PMC9520621.
  12. Zhang, H, Fu, H, Fang, H, Deng, Q, Huang, H, Hou, D et al.. Epigenetic Regulation of Methylation in Determining the Fate of Dental Mesenchymal Stem Cells. Stem Cells Int. 2022;2022 :5015856. doi: 10.1155/2022/5015856. PubMed PMID:36187229 PubMed Central PMC9522499.
  13. Zhang, W, Yu, M, Cao, Y, Zhuang, Z, Zhang, K, Chen, D et al.. An anti-bacterial porous shape memory self-adaptive stiffened polymer for alveolar bone regeneration after tooth extraction. Bioact Mater. 2023;21 :450-463. doi: 10.1016/j.bioactmat.2022.08.030. PubMed PMID:36185742 PubMed Central PMC9486049.
  14. Zheng, A, Wang, X, Xin, X, Peng, L, Su, T, Cao, L et al.. Promoting lacunar bone regeneration with an injectable hydrogel adaptive to the microenvironment. Bioact Mater. 2023;21 :403-421. doi: 10.1016/j.bioactmat.2022.08.031. PubMed PMID:36185741 PubMed Central PMC9483602.
  15. Zhuang, Y, Jiang, S, Yuan, C, Lin, K. The potential therapeutic role of extracellular vesicles in osteoarthritis. Front Bioeng Biotechnol. 2022;10 :1022368. doi: 10.3389/fbioe.2022.1022368. PubMed PMID:36185451 PubMed Central PMC9523151.
  16. Geng, T, Wang, Y, Lin, K, Zhang, C, Wang, J, Liu, Y et al.. Strontium-doping promotes bone bonding of titanium implants in osteoporotic microenvironment. Front Bioeng Biotechnol. 2022;10 :1011482. doi: 10.3389/fbioe.2022.1011482. PubMed PMID:36185426 PubMed Central PMC9520299.
  17. Yang, LY, Chen, YR, Lee, JE, Chen, KW, Luh, HT, Chen, YT et al.. Dental Pulp Stem Cell-Derived Conditioned Medium Alleviates Subarachnoid Hemorrhage-Induced Microcirculation Impairment by Promoting M2 Microglia Polarization and Reducing Astrocyte Swelling. Transl Stroke Res. 2022; :. doi: 10.1007/s12975-022-01083-8. PubMed PMID:36181630 .
  18. de Souza Araújo, IJ, Ferreira, JA, Daghrery, A, Ribeiro, JS, Castilho, M, Puppin-Rontani, RM et al.. Self-assembling peptide-laden electrospun scaffolds for guided mineralized tissue regeneration. Dent Mater. 2022; :. doi: 10.1016/ PubMed PMID:36180310 .
  19. Kim, D, Lee, H, Lee, GH, Hoang, TH, Kim, HR, Kim, GH et al.. Fabrication of bone-derived decellularized extracellular matrix/ceramic-based biocomposites and their osteo/odontogenic differentiation ability for dentin regeneration. Bioeng Transl Med. 2022;7 (3):e10317. doi: 10.1002/btm2.10317. PubMed PMID:36176607 PubMed Central PMC9472025.
  20. Ko, WK, Kim, SJ, Han, GH, Lee, D, Jeong, D, Lee, SJ et al.. Transplantation of neuron-inducing grafts embedding positively charged gold nanoparticles for the treatment of spinal cord injury. Bioeng Transl Med. 2022;7 (3):e10326. doi: 10.1002/btm2.10326. PubMed PMID:36176600 PubMed Central PMC9472004.
  21. Zeng, L, He, H, Sun, M, Gong, X, Zhou, M, Hong, Y et al.. Runx2 and Nell-1 in dental follicle progenitor cells regulate bone remodeling and tooth eruption. Stem Cell Res Ther. 2022;13 (1):486. doi: 10.1186/s13287-022-03140-3. PubMed PMID:36175952 PubMed Central PMC9524038.
  22. Yang, Z, Wang, C, Zhang, X, Li, J, Zhang, Z, Tan, Z et al.. Stem cells from human exfoliated deciduous teeth attenuate trigeminal neuralgia in rats by inhibiting endoplasmic reticulum stress. Korean J Pain. 2022;35 (4):383-390. doi: 10.3344/kjp.2022.35.4.383. PubMed PMID:36175337 .
  23. Liu, Z, Yan, N, Chen, Y, Hu, B. Hepatocyte Growth Factor Promotes Differentiation Potential and Stress Response of Human Stem Cells from Apical Papilla. Cells Tissues Organs. 2022; :. doi: 10.1159/000527212. PubMed PMID:36170806 .
  24. Swain, N, Thakur, M, Pathak, J, Patel, S, Hosalkar, R, Ghaisas, S et al.. Altered immunoexpression of SOX2, OCT4 and Nanog in the normal-appearing oral mucosa of tobacco users. Dent Med Probl. ;59 (3):389-395. doi: 10.17219/dmp/146485. PubMed PMID:36170598 .
  25. Huang, T, Tu, C, Zhou, T, Yu, Z, Wang, Y, Yu, Q et al.. Antifouling poly(PEGMA) grafting modified titanium surface reduces osseointegration through resisting adhesion of bone marrow mesenchymal stem cells. Acta Biomater. 2022; :. doi: 10.1016/j.actbio.2022.09.058. PubMed PMID:36167235 .
  26. Takamatsu, G, Manome, Y, Lee, JS, Toyama, K, Hayakawa, T, Hara-Miyauchi, C et al.. Generation of four iPSC lines from a family harboring a 1p36-35 haplotype linked with bipolar disorder and recurrent depressive disorder: Three-generation patients and a healthy sibling. Stem Cell Res. 2022;64 :102915. doi: 10.1016/j.scr.2022.102915. PubMed PMID:36166871 .
  27. Yu, T, Zhang, L, Dou, X, Bai, R, Wang, H, Deng, J et al.. Mechanically Robust Hydrogels Facilitating Bone Regeneration through Epigenetic Modulation. Adv Sci (Weinh). 2022; :e2203734. doi: 10.1002/advs.202203734. PubMed PMID:36161289 .
  28. Zhao, Y, Huang, Y, Liu, H, Tan, K, Wang, R, Jia, L et al.. Macrophages with Different Polarization Phenotypes Influence Cementoblast Mineralization through Exosomes. Stem Cells Int. 2022;2022 :4185972. doi: 10.1155/2022/4185972. PubMed PMID:36159746 PubMed Central PMC9507802.
  29. Lu, J, Li, R, Ni, S, Xie, Y, Liu, X, Zhang, K et al.. Metformin carbon nanodots promote odontoblastic differentiation of dental pulp stem cells by pathway of autophagy. Front Bioeng Biotechnol. 2022;10 :1002291. doi: 10.3389/fbioe.2022.1002291. PubMed PMID:36159662 PubMed Central PMC9506707.
  30. Yamaguchi, T, Hosomichi, K, Shirota, T, Miyamoto, Y, Ono, W, Ono, N et al.. Primary failure of tooth eruption: Etiology and management. Jpn Dent Sci Rev. 2022;58 :258-267. doi: 10.1016/j.jdsr.2022.08.002. PubMed PMID:36159186 PubMed Central PMC9489741.
  31. Abedi, N, Rajabi, N, Kharaziha, M, Nejatidanesh, F, Tayebi, L. Layered scaffolds in periodontal regeneration. J Oral Biol Craniofac Res. ;12 (6):782-797. doi: 10.1016/j.jobcr.2022.09.001. PubMed PMID:36159068 PubMed Central PMC9489757.
  32. Krishna, M, Shetty, A, Manjappa, AB, Shetty, V, Hegde, MN, Kumar, BM et al.. Comparative characterization and analysis of telomere length in stem cells derived from deciduous and permanent teeth. Dent Res J (Isfahan). 2022;19 :64. . PubMed PMID:36159052 PubMed Central PMC9490240.
  33. Tsuchiya, A, Natsui, K, Ishii, Y, Koseki, Y, Takeda, N, Tomiyoshi, K et al.. Small extracellular vesicles and liver diseases: From diagnosis to therapy. World J Hepatol. 2022;14 (7):1307-1318. doi: 10.4254/wjh.v14.i7.1307. PubMed PMID:36158910 PubMed Central PMC9376785.
  34. Yuan, SM, Yang, XT, Zhang, SY, Tian, WD, Yang, B. Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications. World J Stem Cells. 2022;14 (7):435-452. doi: 10.4252/wjsc.v14.i7.435. PubMed PMID:36157522 PubMed Central PMC9350620.
  35. Wentworth, KL, Lalonde, RL, Groppe, JC, Brewer, N, Moody, T, Hansberry, S et al.. Functional testing of BMP pathway variants identified on whole exome sequencing in a patient with delayed-onset fibrodysplasia ossificans progressiva (FOP) using ACVR1R206H -specific human cellular and zebrafish models. J Bone Miner Res. 2022; :. doi: 10.1002/jbmr.4711. PubMed PMID:36153796 .
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  37. Same, S, Navidi, G, Samee, G, Abedi, F, Aghazadeh, M, Milani, M et al.. Gentamycin-loaded Halloysite-based Hydrogel Nanocomposites for Bone Tissue Regeneration: Fabrication, Evaluation of the Antibacterial Activity and Cell Response. Biomed Mater. 2022; :. doi: 10.1088/1748-605X/ac94ad. PubMed PMID:36150376 .
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  41. Sugiaman, VK, Djuanda, R, Pranata, N, Naliani, S, Demolsky, WL, Jeffrey, et al.. Tissue Engineering with Stem Cell from Human Exfoliated Deciduous Teeth (SHED) and Collagen Matrix, Regulated by Growth Factor in Regenerating the Dental Pulp. Polymers (Basel). 2022;14 (18):. doi: 10.3390/polym14183712. PubMed PMID:36145860 PubMed Central PMC9503223.
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  43. Simonovic, J, Toljic, B, Lazarevic, M, Markovic, MM, Peric, M, Vujin, J et al.. The Effect of Liquid-Phase Exfoliated Graphene Film on Neurodifferentiation of Stem Cells from Apical Papilla. Nanomaterials (Basel). 2022;12 (18):. doi: 10.3390/nano12183116. PubMed PMID:36144905 PubMed Central PMC9502655.
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