Dental Stem Cells

The Mesenchymal Stem Cells found in Teeth are now the most researched Stem Cells in the Scientific Literature.

Dental Stem Cell Research

  1. Lee, DW, Han, HS, Kim, YB, Seok, S, Yoon, G, Kim, H et al.. BMP9-loaded collagen scaffold promotes periodontal regeneration via microenvironmental modulation of PDLSCs and macrophages. Biomaterials. 2026;338 (Pt A):124591. doi: 10.1016/j.biomaterials.2026.124591. PubMed PMID:42710334 .
  2. Saghaei Bagheri, H, Biray Avci, C, Didar Khosrowshahi, N, Vaziri Nezamdoust, F, Rashidi, S, Khoshfetrat, AB et al.. Low-level laser irradiation stimulated tumoricidal impacts and dose-dependent modulation of Wnt signaling in three-dimensional human colorectal cancer microspheres. Lasers Med Sci. 2026;41 (1):. doi: 10.1007/s10103-026-05023-y. PubMed PMID:42706457 .
  3. Brandi, ML, AbuAlrob, H, Chang, W, Clarke, BL, Collins, MT, DiMarchi, R et al.. Hypoparathyroidism: translating science from the laboratory to the clinic. Lancet Diabetes Endocrinol. 2026; :. doi: 10.1016/S2213-8587(26)00188-9. PubMed PMID:42705258 .
  4. GBD 2023 Second-hand smoke Collaborators. Global, regional, and national prevalence of second-hand smoke and attributable disease burden in 204 countries and territories, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023. Lancet Public Health. 2026; :. doi: 10.1016/S2468-2667(26)00168-4. PubMed PMID:42705247 .
  5. Sheshadri, P, Bhaskar, S, Gowda, J, Banerjee, S, Duchen, MR, Prasanna, J et al.. SHH mediated human dopaminergic neuron differentiation is facilitated by transcription factor ZIC3. Biochim Biophys Acta Mol Cell Res. 2026;1873 (8):120213. doi: 10.1016/j.bbamcr.2026.120213. PubMed PMID:42702224 .
  6. Sehar, K, Kumar, A, Parwaiz, S, Patel, SS, Irfan, M, M, K et al.. DFDBA with or without allogenic human dental pulp derived mesenchymal stem cells in treatment of mandibular class II furcation defects. Bioinformation. 2026;22 (6):3357-3361. doi: 10.6026/973206300223357. PubMed PMID:42701595 PubMed Central PMC13545914.
  7. Abd-Elmonsif, NM, Morsy, A, Deeb, ME. Enhanced odontoblast regeneration and anti-inflammatory effects of nanocurcumin-loaded BM-MSC-derived exosomes in an LPS-induced periodontitis rat model. BMC Oral Health. 2026;26 (1):. doi: 10.1186/s12903-026-09697-2. PubMed PMID:42698076 PubMed Central PMC13543616.
  8. Hu, YJ, Liu, Y, Yang, Y. From Stone to Sponge: Hippo/YAP Mechanotransduction Empowers Cell Fates and Functions in Bone and Liver. Cold Spring Harb Perspect Biol. 2026; :. doi: 10.1101/cshperspect.a041911. PubMed PMID:42697695 .
  9. Sinsareekul, C, Phothichailert, S, Suwittayarak, R, Trachoo, V, Kornsuthisopon, C, Sukarawan, W et al.. Cytotoxicity and Bioactivity of Five Hydraulic Silicate Cements in Human Dental Pulp Cells at Different Setting Stages. Int Dent J. 2026;76 (6):111144. doi: 10.1016/j.identj.2026.111144. PubMed PMID:42696938 .
  10. Avery, D, Sheakley, L, Gary, M, Davis, S, Morandini, L, Hotchkiss, KM et al.. Biomaterial-Activated Macrophage-T Cell Crosstalk Promotes Myofibroblastic Differentiation of Mesenchymal Stem Cells. J Biomed Mater Res A. 2026;114 (9):e70146. doi: 10.1002/jbm.a.70146. PubMed PMID:42695453 .
  11. Lima, BC, Coutinho, MA, Felizardo Dos Santos, PA, Grillo, R, Brozoski, MA, Melhem-Elias, F et al.. Biomimetic osteochondral regeneration of the TMJ condyle: integrating BMP-2 osteoinduction, MSC-mediated fibrochondrogenesis, and gradient 3D-printed scaffolds. J Oral Biol Craniofac Res. 2026;16 (4):101501. doi: 10.1016/j.jobcr.2026.101501. PubMed PMID:42694986 PubMed Central PMC13540667.
  12. Takematsu, E, Lachmansingh, RN, Johnston, K, Hou, S, Bailey, E, Wang, Y et al.. Regional diversity of cranial skeletal stem cells governs bone morphogenetic protein-2 mediated bone regeneration. Nat Commun. 2026;17 (1):. doi: 10.1038/s41467-026-76286-w. PubMed PMID:42693126 PubMed Central PMC13542091.
  13. Liu, S, Shao, J, Yang, Q, Liu, H, Liu, Y, Zheng, Z et al.. SIRT1 promotes endothelial activity and osteogenesis in vitro and ameliorates age-related skeletal regeneration defects in vivo. Stem Cell Reports. 2026; :103063. doi: 10.1016/j.stemcr.2026.103063. PubMed PMID:42692013 .
  14. Shang, C, Zhao, W, Song, Y, Zhang, Y, Xu, X, Xu, L et al.. Astragalus polysaccharide attenuates inflammation and restores odontogenic/osteogenic differentiation of hDPSCs. Arch Oral Biol. 2026;192 :106739. doi: 10.1016/j.archoralbio.2026.106739. PubMed PMID:42691951 .
  15. Yang, Y, Du, W, Yang, D, Luo, Y, Zhou, Q, Zuo, D et al.. Membrane Potential Hyperpolarization Controls the Osteogenic Differentiation of Human Dental Follicle Stem Cells by Increasing Intracellular Ca2+ Levels. Front Biosci (Landmark Ed). 2026;31 (8):53140. doi: 10.31083/FBL53140. PubMed PMID:42689977 .
  16. Tsai, YS, Cheng, SJ, Chuang, TL, Chang, SF, Lin, FH, Lin, CP et al.. Development and characterization of an exosome-loaded biomimetic hydroxyapatite/gelatin scaffold for enhanced dental pulp regeneration. J Dent Sci. 2026;21 (2):985-996. doi: 10.1016/j.jds.2025.11.017. PubMed PMID:42689128 PubMed Central PMC13536453.
  17. Torelli, F. Optogenetic control of odontoblastic differentiation in dental pulp stem cells (DPSC). J Dent Sci. 2026;21 (3):1756-1763. doi: 10.1016/j.jds.2025.07.3543. PubMed PMID:42689111 PubMed Central PMC13536420.
  18. Sun, YS, Lin, KY, Chen, WC, Huang, HH. Dual-layer biphasic calcium phosphates/tantalum pentoxide coating on titanium for concurrent biocorrosion resistance and enhanced biocompatibility. J Dent Sci. 2026;21 (3):1449-1458. doi: 10.1016/j.jds.2025.07.3446. PubMed PMID:42689074 PubMed Central PMC13536408.
  19. Nugraha, AP, Hong, G, Yang, K, Narmada, IB, Rantam, FA, Ernawati, DS et al.. Mesenchymal stem cells derived from gingiva normoxic or hypoxic-preconditioning allogenous transplantation affect orthodontic tooth movement in vivo. J Dent Sci. 2026;21 (3):1801-1808. doi: 10.1016/j.jds.2025.07.3548. PubMed PMID:42689049 PubMed Central PMC13536401.
  20. Song, SE, Yun, G, Kim, CH, Yoon, JY, Kim, HY, Kim, HJ et al.. Dual effects of 1α,25-dihydroxyvitamin D3 on inflammation and osteogenic differentiation in lipopolysaccharide-stimulated dental pulp stem cells. J Dent Sci. 2026;21 (3):1948-1957. doi: 10.1016/j.jds.2025.07.3564. PubMed PMID:42689044 PubMed Central PMC13536342.
  21. Sirisereephap, K, Pasanaphong, K, Osathanon, T, Promoppatum, P, Maekawa, T, Srimaneepong, V et al.. Synergistic effects of biodegradable magnesium alloy and erythromycin on osteogenic activity. J Dent Sci. 2026;21 (3):1627-1635. doi: 10.1016/j.jds.2025.07.3462. PubMed PMID:42688957 PubMed Central PMC13536291.
  22. Kalantari, M, Malekhoseini, N, Malekpour Afshar, R, Fouladi, S. Overexpression of MIEN1 in Oral Squamous Cell Carcinoma: Correlation with Tumor Invasion and Lymph Node Metastasis. J Dent (Shiraz). 2026;27 (3):252-258. doi: 10.30476/dentjods.2025.106409.2659. PubMed PMID:42688861 PubMed Central PMC13535677.
  23. Hayashi, I, Nakamura-Yamada, S, Abe, K, Ito, E, Katagiri, W, Miyazaki, T et al.. The utility of 3D nanostructured polyglycolic acid fibers for novel bone regenerative medicine. J Dent Sci. 2026;21 (3):1892-1903. doi: 10.1016/j.jds.2025.07.3558. PubMed PMID:42688652 PubMed Central PMC13536381.
  24. Sawutdeechaikul, P, Pimpakan, T, Van Phan, T, Rosa, V, Ferreira, JN. From human dental pulp stem cells to functional cholinergic neurons: An optimized neurogenic differentiation protocol for new approach methodologies. J Dent Sci. 2026;21 (2):781-791. doi: 10.1016/j.jds.2025.10.025. PubMed PMID:42688638 PubMed Central PMC13536296.
  25. Belenichev, I, Popazova, O, Dmytriieva, O, Chertov, S, Bukhtiyarova, N, Ryzhenko, V et al.. Molecular cytokine-dependent mechanisms of periodontitis pathogenesis and the potential for pharmacological IL-1 modulation in disease treatment. Front Dent Med. 2026;7 :1849807. doi: 10.3389/fdmed.2026.1849807. PubMed PMID:42688516 PubMed Central PMC13535533.
  26. Luo, H, Li, S, Tian, Q, Gao, J, Li, Z, Zheng, L et al.. Glutathione Primes Mitochondrial Autophagy to Guide Pulp-Dentine Complex Repair. Int Endod J. 2026; :. doi: 10.1111/iej.70240. PubMed PMID:42687338 .
  27. Xing, X, Hao, Y, Zhang, G, Xing, X, Jia, H, Liu, C et al.. Exosomal PSMD1 Derived From Dental Pulp Mesenchymal Stem Cells Promotes Microglial M2 Polarization to Alleviate Spinal Cord Injury. CNS Neurosci Ther. 2026;32 (9):e71133. doi: 10.1002/cns.71133. PubMed PMID:42687121 PubMed Central PMC13538453.
  28. Isogai, S, Okabe, A, Tanaka, K, Nakagawa, T, Izumi, S, Fukuyo, M et al.. Epstein-Barr virus-associated chromatin activation and enhancer engagement in T/NK-cell lymphoproliferative diseases. Blood. 2026; :. doi: 10.1182/blood.2025032640. PubMed PMID:42685000 .
  29. Su, X, Zhang, Y, Lv, T, Wang, B, Pang, R, Guo, F et al.. Photothermal-responsive dexmedetomidine-loaded MPDA-GelMA hydrogel promotes bone regeneration. J Mater Chem B. 2026; :. doi: 10.1039/d6tb01440b. PubMed PMID:42684198 .
  30. Carvalho, LAM, Rodriguez-Sanchez, DN, Müller, KS, Balzani, MFV, Mancilla-Corzo, IJ, d'Ávila, MA et al.. Multifunctional Three-Dimensional Bioprinted Scaffolds Reduce Epidural Fibrosis and Promote Bone Regeneration in a Laminectomy Model. ACS Appl Bio Mater. 2026; :. doi: 10.1021/acsabm.6c01134. PubMed PMID:42683558 .
  31. Kannan, G, Kumar, G, Ravishankar, PL, Solomon, G, Varatharajan, K, Paneerselvan, VE et al.. Exosome-based strategies for periodontal regeneration: Current insights and future prospects (Review). Med Int (Lond). 2026;6 (5):50. doi: 10.3892/mi.2026.334. PubMed PMID:42682920 PubMed Central PMC13531124.
  32. Shao, D, Yao, Z. MicroRNA signatures in inflammatory dental tissues: biomarkers and molecular mechanisms. Front Mol Biosci. 2026;13 :1881450. doi: 10.3389/fmolb.2026.1881450. PubMed PMID:42682623 PubMed Central PMC13530013.
  33. Yamada, M, Hase, H, Kitamura, H, Morie, T, Aoi, S, Ueda, Y et al.. An ALKBH3 Inhibitor HUHS199 Suppresses Proliferation of Glioblastoma Cells by Targeting 1-Methyladenosine on GADD45A mRNA. Chem Biol Drug Des. 2026;108 (3):e70385. doi: 10.1111/cbdd.70385. PubMed PMID:42681921 PubMed Central PMC13534923.
  34. GBD 2023 Asia Pacific Adolescent Health Collaborators. Adolescent health across Asia Pacific, 2000-23: a systematic analysis for the Global Burden of Disease Study 2023. Lancet Child Adolesc Health. 2026;10 (10):731-754. doi: 10.1016/S2352-4642(26)00163-X. PubMed PMID:42679829 .
  35. Abdeen, A, Elmorsy, EM, Hetta, HF, Ibrahim, AN, Behery, M, Allam, AM et al.. Evolution of periodontal ligament stem cells and their laden scaffolds as game changers in oral and maxillofacial reconstruction. Tissue Cell. 2026;104 (Pt 2):103895. doi: 10.1016/j.tice.2026.103895. PubMed PMID:42679616 .
  36. Li, Y, Shi, H, He, W, Qiao, Y, Xue, H, Liu, X et al.. A zinc-iron nanozyme with pH-dependent multi-enzymatic activities for sequential infection control and inflammation resolution in vital pulp therapy. Biomater Sci. 2026; :. doi: 10.1039/d6bm00827e. PubMed PMID:42678408 .
  37. Antunes Teixeira, P, Fernandes de Magalhães Silveira, C, Sigrist de Martin, A, Silveira Bueno, CE, Rangel-Coelho, JP, Ferreira Martinez, E et al.. Effects of resveratrol-enriched endodontic sealants on pulp stem cell viability and collagen production. Acta Odontol Latinoam. 2026;39 (1):36-42. doi: 10.54589/aol.39/1/36. PubMed PMID:42678110 PubMed Central PMC13543400.
  38. Bai, Z, Gui, X, Zhang, B, He, X, Peng, H, Zhou, C et al.. Construction of biomimetic hydroxyapatite bilayer scaffolds via DLP 3D printing for bio-root regeneration. J Mater Chem B. 2026; :. doi: 10.1039/d6tb01226d. PubMed PMID:42677996 .
  39. Wang, X, Hu, X, Sheng, R, Wang, R, Huang, X, Huang, T et al.. Multimodal extracellular osteogenic microenvironment orchestrating with piezoelectric collagen fibrils for promoting bone regeneration. J Mater Chem B. 2026; :. doi: 10.1039/d6tb01059h. PubMed PMID:42677855 .
  40. Kim, W, Park, S, Beom, SW, Choi, S, Yang, HW, Kim, D et al.. Regenerative Nano-scaffolds for Tissue Engineering: From Bench to Clinical Translation. Biomater Res. 2026;30 :0414. doi: 10.34133/bmr.0414. PubMed PMID:42676842 PubMed Central PMC13527211.
  41. Song, J, Song, W, Liu, P, Zhou, Y, Chi, X, You, F et al.. RNA-binding protein OTUD1 maintains skeletal homeostasis by determining mesenchymal stem cell lineage commitment. Cell Rep. 2026;45 (9):117932. doi: 10.1016/j.celrep.2026.117932. PubMed PMID:42671913 .
  42. Ahmad, P, Estrin, NE, Sculean, A, Miron, RJ. Understanding extracellular vesicles in antiaging. Periodontol 2000. 2026; :. doi: 10.1111/prd.70070. PubMed PMID:42670765 .
  43. Zhang, B, Wang, J, Wang, T, Zong, Z, Liu, X, Xu, Z et al.. Targeting Fibrin Deposit Alleviates Periodontitis via Neutrophil Modulation. J Dent Res. 2026; :220345261468280. doi: 10.1177/00220345261468280. PubMed PMID:42670331 .
  44. Nabbout, F, Ghassibe, M, Sabbagh, J. Calcium Channel Subunit Alpha2delta 2 Is Upregulated During Odontoblast-Like Differentiation and Exhibits Higher Basal Expression in Stem Cells From Exfoliated Deciduous Teeth Than in Dental Pulp Stem Cells. Cureus. 2026;18 (7):e113676. doi: 10.7759/cureus.113676. PubMed PMID:42669006 PubMed Central PMC13525845.
  45. de Souza, W, Gemini-Piperni, S, Grenho, L, Ribeiro, F, Wiechers, D, Meneses, J et al.. Titanium dioxide nanoparticles alter mesenchymal stem cell function and exosome signalling: Possible implications in periprosthetic osteolysis. Biomater Adv. 2026;190 :215135. doi: 10.1016/j.bioadv.2026.215135. PubMed PMID:42664867 .
  46. Sarker, MD, Zong, C, Hoang, LAP, Jeong, HJ, Kumar, V, Zhu, E et al.. Nano-layered tendon patch to orchestrate timely interactions between tendon stem/progenitor cells and macrophages. Biomaterials. 2026;337 :124580. doi: 10.1016/j.biomaterials.2026.124580. PubMed PMID:42664711 PubMed Central PMC13542791.
  47. Li, P, Zhang, S, Zhang, W, Zhao, S, Shang, C, Pan, S et al.. Exosomes Loaded With MiR-21 Promote Differentiation of Dental Pulp Stem Cells Into Endothelial Cells. Int Dent J. 2026;76 (5):109790. doi: 10.1016/j.identj.2026.109790. PubMed PMID:42664586 PubMed Central PMC13545710.
  48. Keerthika, MR, Surendran, S, Natanasabapathy, V, Chandrasekaran, S, Vasudevan, A, Baskar, K et al.. Biocompatibility of carbazochrome sodium sulfonate on human dental pulp stem cells: An in vitro investigation. J Conserv Dent Endod. 2026;29 (8):909-915. doi: 10.4103/JCDE.JCDE_457_26. PubMed PMID:42663002 PubMed Central PMC13521543.
  49. Panchal, P, Rauwel, P, Coconubo-Guio, L, Hermosa, G, Gautam, S, Nehra, SP et al.. Mechanistic Investigation of Visible-Light-Driven Photocatalysis in Bio-Synthesized Graphitic Carbon Nitride/MgO Nanocomposites Toward Safranine Orange Dye. ACS Omega. 2026;11 (33):49651-49668. doi: 10.1021/acsomega.6c03815. PubMed PMID:42662624 PubMed Central PMC13520051.
  50. Khurshid, G, Chaithanya, R, Panda, A, Changani, K, Menat, S, Pandya, H et al.. Clinical efficiency of mesenchymal stem cells for bone regeneration and osseointegration. Bioinformation. 2026;22 (5):2949-2952. doi: 10.6026/973206300222949. PubMed PMID:42662317 PubMed Central PMC13519413.
  51. Qu, Y, Liu, H, Wang, Y, Gao, S, Huang, H, Li, J et al.. ISL1 regulates the differentiation and maintenance of dental epithelial stem cells in the incisor. FEBS J. 2026; :. doi: 10.1111/febs.70713. PubMed PMID:42657520 .
  52. AlMaimouni, Y, Yuan, W, Houtari, S, Moshaverinia, A. Application of dynamic hydrogels for dental pulp regeneration: a comparative study on cellular behavior and inflammatory modulation. Front Dent Med. 2026;7 :1847615. doi: 10.3389/fdmed.2026.1847615. PubMed PMID:42656218 PubMed Central PMC13506308.
  53. Guerrero, J, Ghayor, C, Domínguez, AP, Bhattacharya, I, Weber, FE. Matrix-Bound and Media-Derived Extracellular Vesicles from Mineralized Osteoblasts Exhibit Distinct Osteogenic Activities. Int J Mol Sci. 2026;27 (16):. doi: 10.3390/ijms27167400. PubMed PMID:42653403 PubMed Central PMC13513129.
  54. Masson-Meyers, DS, Omidi, M, Toth, JM. Cytocompatibility and antibacterial properties of copper-magnesium nanoparticles for potential dental applications. J Oral Biosci. 2026;68 (5):100812. doi: 10.1016/j.job.2026.100812. PubMed PMID:42648020 .
  55. Zhao, T, Edwards, AM, Celiz, AD, Jones, JR. Antimicrobial Gelatin Methacryloyl (GelMA)/Bioactive Glass Dental Adhesives. J Funct Biomater. 2026;17 (8):. doi: 10.3390/jfb17080394. PubMed PMID:42646197 PubMed Central PMC13514707.
  56. Shopova, D, Aleksandrov, S, Hristozova, MI. Functional Biomaterials and 3D Bioprinting Approaches for Temporomandibular Joint Reconstruction: A Narrative Review. J Funct Biomater. 2026;17 (8):. doi: 10.3390/jfb17080390. PubMed PMID:42646193 PubMed Central PMC13514935.
  57. Kim, YK, Niu, W, Love, CJ, Spector, M. Mechanotransductive Osteogenesis Through Microarchitectural Stabilization in an Injectable Hydrogel-Mineral System. J Funct Biomater. 2026;17 (8):. doi: 10.3390/jfb17080389. PubMed PMID:42646192 PubMed Central PMC13514390.
  58. Milic, MS, Simonovic, J, Todorovic, VS. Cellular Responses at the Zirconia Dental Implant Interface: A Comprehensive Review. J Funct Biomater. 2026;17 (8):. doi: 10.3390/jfb17080372. PubMed PMID:42646175 PubMed Central PMC13514665.
  59. Pérez-Bohórquez, JM, Acero-Garzón, MC, Gutiérrez-Prieto, SJ, Méndez-Pinzón, HA, Perdomo-Lara, SJ, Rodríguez-Hernández, H et al.. HAp/PLGA/Chitosan Scaffolds Fabricated by Freeze-Drying and 3D Printing for Bone Regeneration: In Vitro Evaluation and Finite Element Analysis. Biomimetics (Basel). 2026;11 (8):. doi: 10.3390/biomimetics11080537. PubMed PMID:42645254 PubMed Central PMC13509448.
  60. Anselmi, C, Aminmansour, S, Mendes Soares, IP, Reis-Prado, AHD, Aminmansour, S, Liepman, O et al.. Polymer Composition Modulates Dental Stem Cell Response and Mineralization in Electrospun Scaffolds for Hard Tissue Regeneration. Biomimetics (Basel). 2026;11 (8):. doi: 10.3390/biomimetics11080518. PubMed PMID:42645235 PubMed Central PMC13510016.
  61. Ijaz, A, Phothichailert, S, Fitri, AR, Zohaib, S, Suwittayarak, R, Kornsuthisopon, C et al.. SHED-derived small extracellular vesicles as potential neuro-immune modulators in Alzheimer's disease. J Oral Biosci. 2026;68 (5):100811. doi: 10.1016/j.job.2026.100811. PubMed PMID:42641475 .
  62. Park, CY, Moon, JH, Lee, SM, Lee, EH, Park, JY, Kim, SY et al.. Serum-induced recovery of proliferative capacity and differentiation potential in aged dental pulp stem cells. Stem Cells Transl Med. 2026;15 (9):. doi: 10.1093/stcltm/szag072. PubMed PMID:42641051 PubMed Central PMC13505630.
  63. Park, HJ, Lee, HS, Lee, Y, Yu, JH, Yang, JW, Ahn, JS et al.. Optimization of a Canine Colon Organoid Platform for Modeling Intestinal Injury and Mesenchymal Stem Cell-Mediated Regeneration. Int J Stem Cells. 2026; :. doi: 10.15283/ijsc26011. PubMed PMID:42638344 .
  64. Ham, DW, Park, CY, Seo, SH, Lee, JE, Lee, EH, Kim, SY et al.. Effect of Adipose-derived Stem Cell Exosomes in Alleviating Experimental Autoimmune Encephalomyelitis by Reducing the Th17-related Immune Response in the Central Nervous System. Curr Neuropharmacol. 2026; :. doi: 10.2174/011570159X464294260728104444. PubMed PMID:42634302 .
  65. Duan, L, Liang, Y, Huang, X. Editorial: Advancing stem cell and extracellular vesicle therapies for autoimmune and cancer treatment. Front Immunol. 2026;17 :1947245. doi: 10.3389/fimmu.2026.1947245. PubMed PMID:42630327 PubMed Central PMC13493547.
  66. Calabrese, TC, Rothermund, K, Syed, FN. Effects of size scaling on cellular dynamics and tissue patterning in tooth root organoids. Front Bioeng Biotechnol. 2026;14 :1801110. doi: 10.3389/fbioe.2026.1801110. PubMed PMID:42630311 PubMed Central PMC13493524.
  67. Dunne, OM, McGarvey, LP, About, I, El-Karim, I, Lundy, FT. Validation of a human peripheral neuronal model for ATP-P2X3 mediated inflammatory pain signalling in the dental pulp. J Endod. 2026; :. doi: 10.1016/j.joen.2026.08.021. PubMed PMID:42628730 .
  68. Yang, S, Dissanayaka, WL. Targeting Hypoxic Pathways for Dental Pulp Regeneration. J Endod. 2026; :. doi: 10.1016/j.joen.2026.08.029. PubMed PMID:42628729 .
  69. Ganapathy, A, Chen, Y, Bhakthavatchalam, V, George, A. Molecular Cues from ECM proteins drive the differentiation of dental pulp stem cells into endothelial cells in the presence of Dentin matrix protein 1. J Endod. 2026; :. doi: 10.1016/j.joen.2026.08.017. PubMed PMID:42628728 .
  70. Morales Valladares, GA, Brizuela Cordero, CI, Betancourt Cisneros, DA, Espinosa Torres, EE, Gallegos Intriago, ME, Palomeque Viteri, KG et al.. Top 100 Most-cited Articles on Stem Cell-based Regenerative Endodontics: A Bibliometric Analysis of Scientific Evolution and Translational Gaps. J Endod. 2026; :. doi: 10.1016/j.joen.2026.08.011. PubMed PMID:42628724 .
  71. Gagliardi, CF, de Castro Santos, A, Warner, K, Garakis, MCV, Nor, J, Cavalcanti, B et al.. N-acetyl cysteine as an adjuvant medication for regenerative endodontics. J Endod. 2026; :. doi: 10.1016/j.joen.2026.08.018. PubMed PMID:42628723 .
  72. Yang, S, Liu, J, Thalakiriyawa, DS, Liu, J, Yang, X, Yiu, CKY et al.. Dental Pulp Stem Cells Transfer Mitochondria via Tunneling Nanotubes to Drive Hypoxic Angiogenesis. J Dent Res. 2026; :220345261473588. doi: 10.1177/00220345261473588. PubMed PMID:42627102 .
  73. Elsherbini, AM, Ezzat, SK. Therapeutic potential of dental follicle-derived stem cells and gold nanoparticles on osteoarthritic temporomandibular joint in guinea pigs (randomized prospective study). BMC Oral Health. 2026;26 (1):. doi: 10.1186/s12903-026-09529-3. PubMed PMID:42625181 PubMed Central PMC13491649.
  74. Ernawati, DS, Fatria, AA, Amiruddin, RSDK, Syafira, AA, Viany, A, Putri, SD et al.. Intraglandular injection of amniotic-derived stem cell metabolites enhances submandibular gland regeneration in diabetic male rats. Odontology. 2026; :. doi: 10.1007/s10266-026-01539-5. PubMed PMID:42624977 .
  75. Alshaibani, DA, Kamadjaja, MJ, Sitalaksmi, RM, Ridwan, RD, Al-Gabri, RS, Ainoosah, S et al.. Effect of hUCMSC-seeded hydroxyapatite-chitosan scaffolds on immunomodulatory cytokine expression during alveolar socket healing: an in vivo study. Odontology. 2026; :. doi: 10.1007/s10266-026-01538-6. PubMed PMID:42624976 .
  76. Maruoka, H, Hasegawa, T, Hongo, H, Yamamoto, T, Abe, M, Kitakamae-Haraguchi, M et al.. Spatiotemporal distribution of α-smooth muscle actin-positive mesenchymal cells during tooth development and mechanical remodeling of the murine periodontal ligament. Odontology. 2026; :. doi: 10.1007/s10266-026-01541-x. PubMed PMID:42624975 .
  77. Phothichailert, S, Gyi, KK, Fitri, AR, Zohaib, S, Ijaz, A, Suwittayarak, R et al.. PTEN-mediated regulation of dental mesenchymal stem cell function: A scoping review. Arch Oral Biol. 2026;191 :106717. doi: 10.1016/j.archoralbio.2026.106717. PubMed PMID:42623834 .
  78. Kordparijaei, E, Ferdosi-Shahandashti, E, Harasani, Z. Innovative Bioengineering Strategies to Enhance Dental Stem Cell Therapeutic Effects in Oncology Treatments. Tissue Eng Part B Rev. 2026; :19373368261469473. doi: 10.1177/19373368261469473. PubMed PMID:42622076 .
  79. Torres, BS, Foster, C, Abrams, SR, Kerosuo, L. Unveiling the Prevalence and Surgical Burden of Neurocristopathies: A Scoping Review and Statistical Analysis. Res Sq. 2026; :. doi: 10.21203/rs.3.rs-10318477/v1. PubMed PMID:42620502 PubMed Central PMC13484851.
  80. Sheikharabi, M, Delkabadi, J, Khosravi, A, Kazeminejad, E. Fabrication and Characterization of a Trans-Activator of Transcription Peptide-Functionalized Collagen-Mineral Trioxide Aggregate Nanofiber Scaffold: Physicochemical Properties and Fibroblast Response. Clin Exp Dent Res. 2026;12 (4):e70437. doi: 10.1002/cre2.70437. PubMed PMID:42619393 PubMed Central PMC13490925.
  81. Bahrami, R, Ebrahimi, A, Mehrjouei, M. Potential impact of low-level laser therapy on Wnt/β-catenin signaling pathway for regenerative endodontic applications: A literature review. Photodiagnosis Photodyn Ther. 2026; :105616. doi: 10.1016/j.pdpdt.2026.105616. PubMed PMID:42617719 .
  82. Soi, S, Sharma, M, Sushant, S, Mrinalini, M, Saini, SK, Dave, A et al.. Radiation-related caries in oral cancer: Molecular pathogenesis, cellular mechanisms, and contemporary management paradigms. J Cancer Res Ther. 2026;22 (3):465-473. doi: 10.4103/jcrt.jcrt_2426_25. PubMed PMID:42617011 .
  83. Han, Y, Ge, C, Kamath, RA, Kaartinen, V, Franceschi, RT. Roles of integrin β1 and discoidin domain receptor 2 in cranial regeneration and skeletal progenitor cell function. Int J Oral Sci. 2026;18 (1):. doi: 10.1038/s41368-026-00455-2. PubMed PMID:42613320 PubMed Central PMC13486828.
  84. GBD 2023 HIV Collaborators. Global, regional, and national burden of HIV/AIDS, 1990-2023, with the estimated burden attributable to intimate partner violence and forecasted impacts of funding cuts through 2030: results from the Global Burden of Disease Study 2023. Lancet HIV. 2026; :. doi: 10.1016/S2352-3018(26)00147-5. PubMed PMID:42612664 .
  85. He, X, Liang, D, Zhao, X, Liu, K, Zhang, Z, Li, M et al.. Effect of Notoginsenoside R1 on reparative dentin formation via regulating the function of human dental pulp stem cells. Tissue Cell. 2026;104 (Pt 1):103858. doi: 10.1016/j.tice.2026.103858. PubMed PMID:42612582 .
  86. Shi, J, Lin, S, Yan, J, Tang, W, Wu, X, Ding, S et al.. p21 Inhibition Rescues Radiation-Induced Osteogenic Dysfunction and Promotes Bone Regeneration in Osteoradionecrosis of the Jaw via the Rb-Smad2/3-Runx2 Axis. Oral Dis. 2026; :. doi: 10.1111/odi.70408. PubMed PMID:42612232 .
  87. Bucchi, C, Baeza-Fernández, J, Benavente, D, Arteaga, S, Godoy, K, Zamorano, M et al.. Fabrication of a Vertically Stacked Dentin-Pulp Complex Organ-on-a-Chip Device Using a Human Dentin Disc. J Vis Exp. 2026; (234):. doi: 10.3791/71713. PubMed PMID:42611725 .
  88. Pei, Y, Dong, C. Dental Pulp Regeneration: A Comprehensive Review of Stem Cells, Biomaterials, and Bioactive Cues. Stem Cell Rev Rep. 2026; :. doi: 10.1007/s12015-026-11214-5. PubMed PMID:42611418 .
  89. Nakajima, I, Shimane, M, Holmstrom, G, Miyaoka, Y. Derivation of human post-mitotic cardiomyocytes from tetraploid iPSCs. Commun Biol. 2026;9 (1):. doi: 10.1038/s42003-026-10763-2. PubMed PMID:42608426 PubMed Central PMC13483045.
  90. Amer, MA, Mansour, AM, Grawish, M, Abou Elkhier, M. Effect of extracellular vesicles derived from either blood or dental pulp stem cells on human dental pulp stem cells: an in vitro study. BDJ Open. 2026;12 (1):. doi: 10.1038/s41405-026-00463-8. PubMed PMID:42608392 PubMed Central PMC13483047.
  91. Kornsuthisopon, C, Chansaenroj, A, Phothichailert, S, Gedik, B, Zhang, C, Nowwarote, N et al.. Integrin-Associated Signalling Regulates Jagged1-Induced Osteogenic Differentiation of Human Dental Pulp Stem Cells. Int Dent J. 2026;76 (5):109808. doi: 10.1016/j.identj.2026.109808. PubMed PMID:42607518 PubMed Central PMC13508636.
  92. Zhang, S, Pan, J, Lv, J, Lin, Y, Shi, Y, Cheng, L et al.. Dental mesenchymal stem cells under inflammatory condition: A potential candidate for stem cell therapy. Tissue Cell. 2026;104 (Pt 1):103846. doi: 10.1016/j.tice.2026.103846. PubMed PMID:42607423 .
  93. Yang, M, Lai, H, Wu, F, Luo, W, Zhan, P, Lin, Z et al.. Spatial Transcriptomics-Inspired Targeted Hydrogel for Dental Pulp Therapy via Strengthen Macrophage Communication. Adv Healthc Mater. 2026; :e71573. doi: 10.1002/adhm.71573. PubMed PMID:42604446 .
  94. Sniecinski, I, Seghatchian, J. Expert insights into AI-assisted platelet bioproducts for patient-centered care in selected clinical scenarios and regenerative applications: From conventional concentrates to regenerative medicine. Transfus Apher Sci. 2026;65 (5):104516. doi: 10.1016/j.transci.2026.104516. PubMed PMID:42603432 .
  95. Yu, Y, Chen, H, Zheng, J, Liu, S, Wang, X, Xing, C et al.. PARK7/HSPB1-Mediated Neuroprotective Effects of SHED in an In vitro Parkinson's Disease Model. Neurochem Res. 2026;51 (4):. doi: 10.1007/s11064-026-04854-z. PubMed PMID:42599608 .
  96. Feng, X, Xie, D, Zhou, Q, Lei, W, He, Y, Zhang, C et al.. Field-ridge structured bioactive Zn-based scaffold promotes bone regeneration via cellular mechanotransduction. Bioact Mater. 2027;67 :213-229. doi: 10.1016/j.bioactmat.2026.07.048. PubMed PMID:42598026 PubMed Central PMC13471069.
  97. Pourmohammadi-Nejad, F, Irannezhad, A, Abazarpour, R, Abedi, P, Yousefi-Ahmadipour, A. A regenerative strategy for vital pulp therapy: Platelet-rich fibrin augments stem cell viability and pluripotency in bioactive cement environments. Biochem Biophys Rep. 2026;47 :102739. doi: 10.1016/j.bbrep.2026.102739. PubMed PMID:42597550 PubMed Central PMC13469813.
  98. Campbell, A, Lin, K, Ngu, J, Ahlstrand, CR, Kohwi-Shigematsu, T, Zhang, Y et al.. Spatial Regulation of Preameloblast Development in Response to Distal Mouse Incisor Injury. Calcif Tissue Int. 2026;117 (1):. doi: 10.1007/s00223-026-01571-1. PubMed PMID:42595916 PubMed Central PMC13473234.
  99. Gadelha, SV, Bontempi, AC, Bispo Vieira de Melo, N, Kury, M, Andia, DC, Lima, AF et al.. Magnesium-containing Calcium Silicate Sealer Modulates Bioactive Gene Expression in Immortalized Human Periodontal Ligament Stem Cells. J Endod. 2026; :. doi: 10.1016/j.joen.2026.08.006. PubMed PMID:42595254 .
  100. Yang, Y, Li, X, Tang, Q, Zhang, C, Chen, Z, Liu, W et al.. Punicalagin Enhances Odontogenic Differentiation and Reparative Dentin Formation via Wnt/β-Catenin Signalling. Int Dent J. 2026;76 (5):109801. doi: 10.1016/j.identj.2026.109801. PubMed PMID:42594707 PubMed Central PMC13499171.
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