Dental Stem Cells

The Mesenchymal Stem Cells found in Teeth are now the most researched Stem Cells in the Scientific Literature.

Dental Stem Cell Research

  1. Daneshvar, A, MomeniAmjadi, A, Azadi, A, Baniameri, S, Kadkhodazadeh, M. Therapeutic potential of dental mesenchymal stem cells versus mesenchymal stem cells from other sources: a systematic review of animal studies. BMC Oral Health. 2025; :. doi: 10.1186/s12903-025-07100-0. PubMed PMID:41354918 .
  2. Zhang, Q, Huang, S, Liu, X, Zhang, M, Sun, J, Liu, M et al.. Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs. Stem Cell Res Ther. 2025; :. doi: 10.1186/s13287-025-04849-7. PubMed PMID:41354828 .
  3. Sahadi, BO, Mendes Soares, IP, Gifford, C, Anselmi, C, Hebling, J, Giannini, M et al.. Transdentinal effects of flavonoid-based primers applied to caries-affected dentin on pulp cells. Clin Oral Investig. 2025;30 (1):1. doi: 10.1007/s00784-025-06693-8. PubMed PMID:41354703 .
  4. Mottaghi, M, Jafari, F, Nejati, M, Farshad, F, Khorshidi Asl, Z, Azmoudeh, F et al.. Mitochondrial DNA mutations in head and neck squamous cell carcinoma: a systematic review and meta-analysis. BMC Cancer. 2025; :. doi: 10.1186/s12885-025-15386-0. PubMed PMID:41353392 .
  5. Neves, LBM, Lima, BC, Coutinho de Mello, R, Baldessarini, BL, Peres, RV. Intra-articular therapies for synovial joint dysfunction: a comprehensive integrative review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2025; :. doi: 10.1016/j.oooo.2025.10.026. PubMed PMID:41352996 .
  6. Chen, Y, Hu, M, Lam, LY, Chen, L, Lin, S, Li, X et al.. Progress and Perspectives in Allogeneic Cell-Based Pulp Regeneration. Int Endod J. 2025; :. doi: 10.1111/iej.70080. PubMed PMID:41351292 .
  7. Li, A, Zhong, J, Zhang, X, Yang, X, Ruan, Y, Huang, Y et al.. Photobiomodulation-pretreated dental follicle stem cells with enhanced osteogenic function improve alveolar bone regeneration. BMC Oral Health. 2025;25 (1):1874. doi: 10.1186/s12903-025-07224-3. PubMed PMID:41345589 PubMed Central PMC12679786.
  8. Ren, Q, Rong, X, Liu, T, Zhang, Z, Zhang, W, Liu, H et al.. Glucocorticoid impairs angiogenesis-dependent osteogenesis by downregulating EphB4 in endothelial cells. Biochem Pharmacol. 2025;244 :117586. doi: 10.1016/j.bcp.2025.117586. PubMed PMID:41344513 .
  9. Pan, L, Yang, Y, Jia, X, Zhao, R, Wang, Y, Guan, X et al.. proBDNF-SorCS2 Axis Suppresses Osteogenesis and Augments Inflammation of Human Periodontal Ligament Stem Cells in Inflammatory Conditions. Int Dent J. 2025;76 (1):109294. doi: 10.1016/j.identj.2025.109294. PubMed PMID:41343965 .
  10. Balasubramanian, HP, Suresh, N, Koteeswaran, V, Natanasabapathy, V. Resolvin E1 incorporated carboxymethyl chitosan scaffold accelerates repair of dental pulp stem cells under inflammatory conditions: a laboratory investigation. Restor Dent Endod. 2025;50 (4):e40. doi: 10.5395/rde.2025.50.e40. PubMed PMID:41342210 .
  11. De Francesco, F, Zingaretti, N, Quaglia, D, Moro, G, Pin, AD, Cavaleri, MP et al.. Stemness and clinical performance of water-jet technology: A translational study in breast reconstruction. JPRAS Open. 2025;46 :750-769. doi: 10.1016/j.jpra.2025.10.010. PubMed PMID:41341966 PubMed Central PMC12670530.
  12. Yang, K, Yuan, S, Wang, Y, Lin, A, Huo, F, Jin, Z et al.. Comparative analysis of dental-derived stem cells and alternative stem cell sources: properties and regenerative functions. Front Bioeng Biotechnol. 2025;13 :1717849. doi: 10.3389/fbioe.2025.1717849. PubMed PMID:41341098 PubMed Central PMC12669115.
  13. Subramanya, A, Mata, S, Narkedamalli, R, Belle, VS, Dhanushkodi, A, Duncan, HF et al.. Comparing the Bioactive Effects of Ethylenediaminetetraacetic Acid and Maleic Acid on TGF-β1 Release From Dentine and Dental Pulp Stem Cell Activity. Int Endod J. 2025; :. doi: 10.1111/iej.70075. PubMed PMID:41340595 .
  14. Kim, HS, Shin, TH. Canine and feline mesenchymal stem cells: an integrative review of direct comparative studies by species and tissue source. J Vet Sci. 2025;26 (6):e78. doi: 10.4142/jvs.25163. PubMed PMID:41331998 .
  15. Riksen, NP, Netea, MG, Ait-Oufella, H, Chavakis, T, Hajishengallis, G. Trained immunity in cardiovascular disease. Eur Heart J. 2025; :. doi: 10.1093/eurheartj/ehaf982. PubMed PMID:41330410 .
  16. Pragadesh, G, Srinivasan, D, Abishek, CB, Sujathadevi, BK. Evaluation of Antimicrobial Efficacy and Cytotoxicity of Phytoextract from Leucas aspera as a Root Canal Irrigant in Primary Tooth: In Vitro Study. Int J Clin Pediatr Dent. 2025;18 (11):1378-1384. doi: 10.5005/jp-journals-10005-3308. PubMed PMID:41328382 PubMed Central PMC12658424.
  17. Zhang, Q, Chen, H, Cun, J, Liu, Q, Wang, H, Jiang, L et al.. A simple and standardized method supports efficient derivation of clinical-grade human embryonic stem cells under feeder- and xeno-free conditions. Stem Cell Res Ther. 2025; :. doi: 10.1186/s13287-025-04831-3. PubMed PMID:41327340 .
  18. Zekušić, M, Skoko, M, Vukušić, K, Ledinski, M, Mihica, MB, Blažević, D et al.. Deep-freezing and decontamination strategy for a large autologous bone graft with presentation of the osteogenic potential of resident osteoblasts. Stem Cell Res Ther. 2025; :. doi: 10.1186/s13287-025-04839-9. PubMed PMID:41327281 .
  19. Dabkeviciute, GM, Kriauciunas, A. Exosomes as Central Mediators of Host-Pathogen Interactions in Periodontitis: A Systematic Literature Review. Cureus. 2025;17 (10):e95609. doi: 10.7759/cureus.95609. PubMed PMID:41322905 PubMed Central PMC12659857.
  20. Mahmoudi Anzabi, R, Shenasa, N, Jafarian, A, Davodpour, AH, Zareanshahraki, M, Ghasemirad, M et al.. Enhancing Osteogenesis in Dental Implants: ZNF710-AS1 and miR-146a-5p in Smad Signaling Pathway Activation. Int J Mol Cell Med. 2025;14 (3):964-975. doi: 10.22088/IJMCM.BUMS.14.3.964. PubMed PMID:41321965 PubMed Central PMC12664691.
  21. Ravi, R, Arumuganainar, D. Biogenic synthesis of copper oxide nanoparticles using Alpinia calcarata extract promotes osteoblasts differentiation: An In vitro study. J Oral Biol Craniofac Res. 2026;16 (1):66-72. doi: 10.1016/j.jobcr.2025.11.007. PubMed PMID:41321768 PubMed Central PMC12663638.
  22. Shariff, KA, Nugraha, AP, Mohammed, AHM, Narmada, IB, Ardani, IGAW, Ramadhani, NF et al.. Erratum to: Osteoinductivity performance dicalcium phosphate dihydrate-coated porous β-tricalcium phosphate granules in adipose-derived mesenchymal stem cells. Dent Mater J. 2025;44 (6):716. doi: 10.4012/dmj.2024-310-e. PubMed PMID:41320300 .
  23. de Souza, JR, Mendes Soares, IP, Anselmi, C, Sikder, P, Hebling, J, Borges, ALS et al.. Biodegradable and osteoconductive sodium alginate-gelatin/amorphous magnesium phosphate 3D-printed scaffolds for craniofacial bone regeneration. J Mech Behav Biomed Mater. 2026;174 :107284. doi: 10.1016/j.jmbbm.2025.107284. PubMed PMID:41317696 .
  24. Seong, KJ, Lee, SW, Lee, JH, Ko, HM, Nam, TK, Kim, TY et al.. Epigallocatechin-3-gallate Restores X-irradiation-Induced Impairments in Cognitive Function and Hippocampal Neurogenesis by Suppressing the TLR4-NOX3/4 and ROS-NF-κB Pathways in Microglia. Mol Neurobiol. 2025;63 (1):220. doi: 10.1007/s12035-025-05473-5. PubMed PMID:41317232 .
  25. Marcolli, G, Barone, L, Baranzini, N, Rossi, F, Nebuloni, AM, Pulze, L et al.. Tissue regenerative potential of human dental pulp mesenchymal stem cell conditioned medium in wound healing of the medicinal leech. Stem Cell Res Ther. 2025;16 (1):673. doi: 10.1186/s13287-025-04683-x. PubMed PMID:41316374 PubMed Central PMC12679731.
  26. Shindo, Y, Ikezaki, S, Iwayama, T, Otsu, K, Kido, Y, Kakura, K et al.. Basement Membrane of Hertwig's Epithelial Root Sheath Is Involved in Dental Follicle Cell Differentiation into Cementoblasts. Stem Cells Dev. 2025; :. doi: 10.1177/15473287251400301. PubMed PMID:41313673 .
  27. Zhou, Z, Li, D, Zhang, J, Jiang, C. ADAMTS2 Mediates Osteogenic Differentiation of Dental Follicle Stem Cells Under Compressive Stress and Inflammation. Stem Cells Dev. 2025; :. doi: 10.1177/15473287251400300. PubMed PMID:41313669 .
  28. Marcos Batista, J, Rajasekaran, S, Huynh, B, Ghosh, T, Marinho, ME, Corcoran, J et al.. Assessment of physicochemical properties and biological responses of chemically surface-modified microcapsules for self-healing dental restorative materials. Mater Des. 2025;259 :. doi: 10.1016/j.matdes.2025.114910. PubMed PMID:41311641 PubMed Central PMC12652498.
  29. Liu, X, Li, W, Sun, M, Zhang, Y, Wu, Y, Duan, R et al.. [Bioinformatics-based approach to analyze the regulation of let-7 family by RNA-binding protein Lin28 in hDPSCs]. Shanghai Kou Qiang Yi Xue. 2025;34 (5):457-464. . PubMed PMID:41311172 .
  30. Chen, Z, Cai, M, Wang, Y, Li, X, He, Y, Pu, H et al.. Autocrine ECM molecules establish MSC quiescence during incisor development by disrupting WNT ligand trafficking process. Nat Commun. 2025;16 (1):10676. doi: 10.1038/s41467-025-65705-z. PubMed PMID:41309624 PubMed Central PMC12660891.
  31. Wagaskar, P, Suryawanshi, M, Patil, A, Pardeshi, V. Therapeutic potential of third molar-derived dental pulp stem cells in Alzheimer's disease: Current evidence and future directions. Ageing Res Rev. 2025;114 :102949. doi: 10.1016/j.arr.2025.102949. PubMed PMID:41308841 .
  32. Anselmi, C, Dal-Fabbro, R, Abada, H, Mendes Soares, IP, Cardoso, LM, Mahmoud, AH et al.. Bilayer gelatin-methacryloyl scaffold for pulp inflammation suppression and dentin-like tissue regeneration. J Control Release. 2025;389 :114469. doi: 10.1016/j.jconrel.2025.114469. PubMed PMID:41308755 .
  33. Mottaghi, M, Kianbakht, C, Samadian, S, Farshbaf, A, Mirhashemi, M, Ahrari, F et al.. Clinical applications of dental pulp stem cells-derived exosomes in oral and maxillofacial tissue regeneration and repair. Differentiation. 2025;146 :100918. doi: 10.1016/j.diff.2025.100918. PubMed PMID:41308294 .
  34. Rodríguez-Lozano, FJ, Pérez-Guzmán, N, García-Rios, P, García-Bernal, D, Mora, A, López-García, S et al.. In Vitro Evaluation of Novel Resin-Modified Calcium Silicate Cements for Minimally Invasive Vital Pulp Therapy. Int Dent J. 2025;76 (1):109299. doi: 10.1016/j.identj.2025.109299. PubMed PMID:41308279 .
  35. Rahman, I, Henidi, H, Alkahtani, MM, Makhlafi, ZA, ElRefai, S, AlSheddi, MA et al.. Thymoquinone Overcomes Hypoxia-Induced Carboplatin Resistance Through ROS-Independent Apoptosis but Promotes Cancer Stem Cell Enrichment: Implications on Oral Cancer Adaptation and Recurrence. Pharmaceuticals (Basel). 2025;18 (11):. doi: 10.3390/ph18111758. PubMed PMID:41305000 PubMed Central PMC12655494.
  36. Sakthi Mohan, P, Abdul Majid, NB, Susilo, RJK, Kunasekaran, W, Jin, TL, Ee, LS et al.. Exosomal Interventions in Bone and Osteochondral Repair: Mechanisms and Outcomes. Int J Mol Sci. 2025;26 (22):. doi: 10.3390/ijms262211172. PubMed PMID:41303658 PubMed Central PMC12653543.
  37. Smaida, R, Hua, G, Benkirane-Jessel, N, Fioretti, F. Three-Dimensional Models of the Dental Pulp: Bridging Fundamental Biology and Regenerative Therapy. Int J Mol Sci. 2025;26 (22):. doi: 10.3390/ijms262210960. PubMed PMID:41303443 PubMed Central PMC12652750.
  38. Nakamura, K, Iida, N, Hayashi, Y, Futenma, T, Sakatoku, S, Sugita, Y et al.. Periostin-Induced Wnt10a Activation Promotes Dental Pulp Stem Cell Migration During Pulp Regeneration. Life (Basel). 2025;15 (11):. doi: 10.3390/life15111732. PubMed PMID:41302156 PubMed Central PMC12653813.
  39. Alarcón-Apablaza, J, Salazar, LA, Loren, P, Martínez-Cardozo, C, Fuentes, R. Effect of Aging on the Morphofunctional Characteristics of Oral Cavity Mesenchymal Stromal Cells: A Scoping Review. Biomedicines. 2025;13 (11):. doi: 10.3390/biomedicines13112776. PubMed PMID:41301869 PubMed Central PMC12650244.
  40. Li, B, Xu, M, Huang, J, Jia, R. FTO Suppresses Dental Pulp Stem Cell Senescence by Destabilizing NOLC1 mRNA. Biomolecules. 2025;15 (11):. doi: 10.3390/biom15111627. PubMed PMID:41301545 PubMed Central PMC12650298.
  41. Lippi, M, Moimas, S, Braga, L, Santin, Y, Galotta, A, Giacca, M et al.. Epigenetic Drugs Splitomicin, Suberohydroxamic Acid, CPTH6, BVT-948, and PBIT Moderate Fibro-Fatty Development in Arrhythmogenic Cardiomyopathy. Biomolecules. 2025;15 (11):. doi: 10.3390/biom15111565. PubMed PMID:41301483 PubMed Central PMC12650369.
  42. Norahan, MH, Sivarasu, S, Fayzullin, A, Mbanefo, C, Bikmulina, P, Ashurko, I et al.. Bioengineering of Periodontal Tissues: Cell Therapy and Biomaterials Application. Bioengineering (Basel). 2025;12 (11):. doi: 10.3390/bioengineering12111213. PubMed PMID:41301169 PubMed Central PMC12649470.
  43. Han, SH, Han, SB, Park, GS, Kim, NJ, Park, WJ, Park, JB et al.. Clinical Application of Cell-Based Approaches in Maxillary Sinus Floor Augmentation: A Systematic Review and Meta-Analysis. Bioengineering (Basel). 2025;12 (11):. doi: 10.3390/bioengineering12111209. PubMed PMID:41301166 PubMed Central PMC12650367.
  44. Min, Y, Lee, YS, Lee, J, Keum, DY, Gwag, JY, Jeon, SM et al.. The cGAS-STING Pathway in Dementia: An Emerging Mechanism of Neuroinflammation. Brain Sci. 2025;15 (11):. doi: 10.3390/brainsci15111241. PubMed PMID:41300248 PubMed Central PMC12651759.
  45. Xue, H, Zhang, H, Yuan, Y, Jin, X, Huang, H. Promotion of Bone Remodeling in Diabetic Periodontitis by Blocking Plasma Exosomal miR-375-3p. Oral Dis. 2025; :. doi: 10.1111/odi.70132. PubMed PMID:41299821 .
  46. Takakuwa, T, Endo, K, Ozeki, N, Nakagawa, Y, Koga, H, Tomita, M et al.. Enhanced lubricin secretion by human synovial mesenchymal stem cells compared to adipose mesenchymal stem cells. Stem Cell Res Ther. 2025; :. doi: 10.1186/s13287-025-04809-1. PubMed PMID:41299580 .
  47. Das, A, Rajendran, AK, Chandramouli, A, Hwang, NS, Rangasamy, J. Osteogenic and angiogenic gelatin-coated Whitlockite nanoparticles incorporated chitosan composite scaffold for alveolar bone regeneration. Int J Biol Macromol. 2025;335 (Pt 1):149208. doi: 10.1016/j.ijbiomac.2025.149208. PubMed PMID:41297817 .
  48. Mohtadi Hamadani, Y, Evers, L, Myllymaki, SM, Juuri, E, Jussila, M, Gueguen, P et al.. Stem cell specification and niche formation in developing incisor requires actomyosin forces. Stem Cells. 2025; :. doi: 10.1093/stmcls/sxaf074. PubMed PMID:41296682 .
  49. Mota, ME, Marques, MM, Gimenez, T, Ariga, SKK, Santos, TGD, Alves, FA et al.. Extracellular vesicles derived from dental mesenchymal stem cells for regenerative medicine: a scoping review. Mol Biol Rep. 2025;53 (1):116. doi: 10.1007/s11033-025-11270-z. PubMed PMID:41296107 .
  50. Zhu, C, Deng, Y, Xu, J, Wen, J, Huang, Q, Yu, W et al.. The Effect of Titanium Dioxide Nanotubes and Graphene Compounds on the Proliferation and Osteogenic Differentiation of Rat BMSCs. J Funct Biomater. 2025;16 (11):. doi: 10.3390/jfb16110413. PubMed PMID:41295068 PubMed Central PMC12653418.
  51. Kirilova, JN, Vladova, RZ, Petrova, VP, Yantcheva, S, Deliverska, EG, Ishkitiev, ND et al.. Influence of Different Biomaterials Extracted from Autologous Blood on the Cell Migration of Stem Cells from Dental Pulp. J Funct Biomater. 2025;16 (11):. doi: 10.3390/jfb16110398. PubMed PMID:41295053 PubMed Central PMC12653902.
  52. Salazar-Nava, MC, Garcia-Contreras, R, Aranda-Herrera, B, Hernandez-Gomez, G, Jurado, CA, Alshabib, A et al.. In Vitro Evaluation of a Gelatin Type A/PVA Hydrogel Functionalized with Roasted Green Tea (Camellia sinensis). Gels. 2025;11 (11):. doi: 10.3390/gels11110920. PubMed PMID:41294605 PubMed Central PMC12652139.
  53. Potdar, P, Kheur, S, Sanap, A, Bhonde, R, Mante, N, Kharat, A et al.. Stem Cell Secretome Reverse Areca Nut Extract Induced Fibrosis in Human Fibroblast and Patient-Derived Biopsies. J Oral Pathol Med. 2025; :. doi: 10.1111/jop.70090. PubMed PMID:41292374 .
  54. Zhou, H, Wen, P, Liu, Y, Ye, Z, Xiong, W, Liu, Y et al.. Corrigendum to "MiR-138 reprograms dental pulp stem cells into GABAergic neurons via the GATAD2B/MTA3/WNTs axis for stroke treatment" [Biomaterials 325 (2026) 123618]. Biomaterials. 2026;327 :123858. doi: 10.1016/j.biomaterials.2025.123858. PubMed PMID:41290423 .
  55. Fu, Y, Meng, L, Zhang, M, Li, L, Liu, H, Ma, W et al.. ED-71 alleviates OVX-induced osteoporosis by inhibiting macrophage senescence through SIRT1/PGC-1α pathway: A potential therapeutic approach. Bone. 2026;203 :117737. doi: 10.1016/j.bone.2025.117737. PubMed PMID:41290109 .
  56. Kim, Y, Park, SY, Jo, A, Ahn, S, Kwon, J, Jung, EM et al.. Long-term low-dose exposure to polystyrene nanoplastics induces morphological and transcriptional reprogramming to enhance metastatic potential of colorectal cancer cells. Toxicology. 2025;520 :154356. doi: 10.1016/j.tox.2025.154356. PubMed PMID:41290084 .
  57. Vallabhaneni, S, Vankayala, NSG, Chaturvedi, M, Kumar, PM, Nishant, K, Nagate, RR et al.. Stem cells as a therapeutic frontier for advanced periodontal regeneration: a systematic review and meta-analysis. Odontology. 2025; :. doi: 10.1007/s10266-025-01257-4. PubMed PMID:41286230 .
  58. Wang, J, Xie, D, Qu, X, Li, T, Meng, X, Zhang, Z et al.. Ultrasensitive Biocoded SERS Immunoassay for Tracing Molecular Gatekeeper Mfn2 Expression within Single Cells during Stem Cell Differentiation. Anal Chem. 2025; :. doi: 10.1021/acs.analchem.5c04642. PubMed PMID:41284614 .
  59. Inada, E, Saitoh, I, Terajima, M, Kiyokawa, Y, Kubota, N, Yamaza, H et al.. Engineered Human Dental Pulp Stem Cells with Promising Potential for Regenerative Medicine. BioTech (Basel). 2025;14 (4):. doi: 10.3390/biotech14040088. PubMed PMID:41283323 PubMed Central PMC12641844.
  60. Zheng, Y, Tang, Z, Li, L, Li, Z. The research landscape and trends of dental pulp stem cell studies (2010-2025): A bibliometric analysis. Regen Ther. 2025;30 :1013-1023. doi: 10.1016/j.reth.2025.10.021. PubMed PMID:41282493 PubMed Central PMC12636884.
  61. Kornsuthisopon, C, Nowwarote, N, Srisuwan, T, Dissanayaka, WL, Osathanon, T. Regulatory Pathways Governing Odonto/Osteogenic Differentiation in Dental Pulp Stem Cells. Int Endod J. 2025; :. doi: 10.1111/iej.70069. PubMed PMID:41277854 .
  62. Jang, JS, Jung, S, Song, MK, Kim, B, Lee, ZH, Kim, HH et al.. Dhx36 deficiency accelerates BMSC senescence and promotes age-related bone loss. BMB Rep. 2025; :. . PubMed PMID:41276281 .
  63. Perales, SG, Rodriguez, M, Rajasingh, J, Al Dayeh, A, Zhang, Y, Dixon, D et al.. Advancements in 3D in vitro cell culture models for dental research. J Oral Biosci. 2025;67 (4):100702. doi: 10.1016/j.job.2025.100702. PubMed PMID:41274686 .
  64. Xiao, Y, Song, Z, Zeng, D, Yang, Y, Peng, W, Lin, Q et al.. Molecular mechanism of NF-κB-mediated transcriptional activation of MMP12 in lipopolysaccharide-stimulated human dental pulp stem cells. J Oral Biosci. 2025;67 (4):100699. doi: 10.1016/j.job.2025.100699. PubMed PMID:41274683 .
  65. Asada, S, Chiba-Ohkuma, R, Karakida, T, Yamamoto, R, Nonoyama, S, Gomi, K et al.. Fibroblast growth factor 2 promotes matrix vesicle-mediated mineralization of human umbilical cord perivascular cells by regulating phosphate metabolism. J Oral Biosci. 2025;67 (4):100693. doi: 10.1016/j.job.2025.100693. PubMed PMID:41274677 .
  66. Tobita, M, Arita, A. Challenges and prospects for popularizing cell therapy in the dentistry in Japan. J Oral Biosci. 2025;67 (4):100692. doi: 10.1016/j.job.2025.100692. PubMed PMID:41274676 .
  67. Baldeon-Gutierrez, R, Ohkura, N, Yoshiba, N, Takahara, S, Gomez-Kasimoto, S, Ida, T et al.. Hyperglycemia in obese type 2 diabetes mellitus rats affects pulp wound healing. J Oral Biosci. 2025;67 (4):100683. doi: 10.1016/j.job.2025.100683. PubMed PMID:41274671 .
  68. Hasuike, A, Watanabe, N, Byrd, KM, Chaurasia, A, Sato, S, Imai, K et al.. Potential interference of the herpes simplex virus with periodontal regeneration: a narrative review. Clin Oral Investig. 2025;29 (12):582. doi: 10.1007/s00784-025-06661-2. PubMed PMID:41273445 .
  69. Zhao, Z, Chen, L, Zhu, S, Yu, H, Chen, Y, Song, J et al.. Periodontal ligament stem cells in tissue remodeling: from mechanical forces to inflammatory signals. Stem Cell Res Ther. 2025;16 (1):653. doi: 10.1186/s13287-025-04777-6. PubMed PMID:41272792 PubMed Central PMC12639658.
  70. Du, W, Geng, P, Lian, Z, Sun, Y, Zhou, Y, Guo, C et al.. DPSCs-Exos promote OPCs differentiation and white matter repair via Myl9-mediated PRMT5 nucleation after ischemic stroke. J Cereb Blood Flow Metab. 2025; :271678X251399014. doi: 10.1177/0271678X251399014. PubMed PMID:41272428 PubMed Central PMC12640283.
  71. Li, Z, Chu, X, Guo, J, Xiang, Y, Luan, Y, Xing, H et al.. Resveratrol delays senescence of human dental pulp stem cells via activating the SIRT1-mitochondrial autophagy. Sci Rep. 2025;15 (1):41354. doi: 10.1038/s41598-025-25240-9. PubMed PMID:41272063 PubMed Central PMC12639125.
  72. Liu, SW, Ang, CS, Paolini, R, Moses, RL, Sloan, AJ. Comparative proteomic analysis of Porphyromonas gingivalis challenged human dental pulp stem cells. Sci Rep. 2025; :. doi: 10.1038/s41598-025-29191-z. PubMed PMID:41272050 .
  73. Liu, H, Zhang, J, Zhong, W, Li, S, Jing, L, Cui, X et al.. Harnessing dental stem cell-derived synovial cells for IBD therapy: dual modulation of gut immunity and crypt repair. EBioMedicine. 2025;122 :106039. doi: 10.1016/j.ebiom.2025.106039. PubMed PMID:41270582 PubMed Central PMC12670579.
  74. Liu, M, Wang, X, Zhou, H, Yang, X, Chen, GY, Yang, P et al.. Transplantation of Macrophages Pretreated With Gingival Mesenchymal Stem Cell Conditioned Medium as a Potential Cell Therapy for Promoting Periodontal Tissue Regeneration in Rats With Experimental Periodontitis. Cell Biol Int. 2026;50 (1):e70104. doi: 10.1002/cbin.70104. PubMed PMID:41268631 .
  75. Kunwong, N, Wongrakpanich, A, Amornphimoltham, P, Dechkunakorn, S, Srikhirin, T, Saranpuetti, C et al.. Optimized delivery of RNA silencing prolyl hydroxylase domain 2 for enhanced angiogenesis and osteogenesis using bioactive glass scaffolds. Sci Rep. 2025;15 (1):40988. doi: 10.1038/s41598-025-24808-9. PubMed PMID:41266661 PubMed Central PMC12634668.
  76. Wang, D, Fang, X, Deng, Y, Wen, X, Liu, O, Xu, J et al.. MRAP mediated adipocyte differentiation by thymic mesenchymal stromal cells contributes to thymic involution. Nat Commun. 2025;16 (1):10210. doi: 10.1038/s41467-025-64973-z. PubMed PMID:41266306 PubMed Central PMC12635226.
  77. Saravana Karthikeyan, B, Mahalaxmi, S, Rajkumar, G, Dhivya, V. Biomineralization and anticariogenic effect of nanocomposite suspensions of eggshell-derived hydroxyapatite and carboxymethyl chitosan on demineralized enamel: A laboratory investigation. Int J Biol Macromol. 2025;334 (Pt 2):149113. doi: 10.1016/j.ijbiomac.2025.149113. PubMed PMID:41265605 .
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